These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 24021214)

  • 1. Structure-based ligand discovery targeting orthosteric and allosteric pockets of dopamine receptors.
    Lane JR; Chubukov P; Liu W; Canals M; Cherezov V; Abagyan R; Stevens RC; Katritch V
    Mol Pharmacol; 2013 Dec; 84(6):794-807. PubMed ID: 24021214
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.
    Guitart X; Navarro G; Moreno E; Yano H; Cai NS; Sánchez-Soto M; Kumar-Barodia S; Naidu YT; Mallol J; Cortés A; Lluís C; Canela EI; Casadó V; McCormick PJ; Ferré S
    Mol Pharmacol; 2014 Oct; 86(4):417-29. PubMed ID: 25097189
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists.
    Furman CA; Roof RA; Moritz AE; Miller BN; Doyle TB; Free RB; Banala AK; Paul NM; Kumar V; Sibley CD; Newman AH; Sibley DR
    Eur Neuropsychopharmacol; 2015 Sep; 25(9):1448-61. PubMed ID: 25583363
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptors.
    Silvano E; Millan MJ; Mannoury la Cour C; Han Y; Duan L; Griffin SA; Luedtke RR; Aloisi G; Rossi M; Zazzeroni F; Javitch JA; Maggio R
    Mol Pharmacol; 2010 Nov; 78(5):925-34. PubMed ID: 20702763
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biased signaling agonist of dopamine D3 receptor induces receptor internalization independent of β-arrestin recruitment.
    Xu W; Reith MEA; Liu-Chen LY; Kortagere S
    Pharmacol Res; 2019 May; 143():48-57. PubMed ID: 30844536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation.
    Kim KM; Gainetdinov RR; Laporte SA; Caron MG; Barak LS
    J Biol Chem; 2005 Apr; 280(13):12774-80. PubMed ID: 15687500
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Factors Governing Selectivity of Dopamine Receptor Binding Compounds for D2R and D3R Subtypes.
    Hayatshahi HS; Luedtke RR; Taylor M; Chen PJ; Blass BE; Liu J
    J Chem Inf Model; 2021 Jun; 61(6):2829-2843. PubMed ID: 33988991
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hybrid ortho/allosteric ligands for the adenosine A(1) receptor.
    Narlawar R; Lane JR; Doddareddy M; Lin J; Brussee J; Ijzerman AP
    J Med Chem; 2010 Apr; 53(8):3028-37. PubMed ID: 20345101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity.
    Ananthan S; Saini SK; Zhou G; Hobrath JV; Padmalayam I; Zhai L; Bostwick JR; Antonio T; Reith ME; McDowell S; Cho E; McAleer L; Taylor M; Luedtke RR
    J Med Chem; 2014 Aug; 57(16):7042-60. PubMed ID: 25126833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors.
    Michino M; Donthamsetti P; Beuming T; Banala A; Duan L; Roux T; Han Y; Trinquet E; Newman AH; Javitch JA; Shi L
    Mol Pharmacol; 2013 Dec; 84(6):854-64. PubMed ID: 24061855
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular determinants of selectivity and efficacy at the dopamine D3 receptor.
    Newman AH; Beuming T; Banala AK; Donthamsetti P; Pongetti K; LaBounty A; Levy B; Cao J; Michino M; Luedtke RR; Javitch JA; Shi L
    J Med Chem; 2012 Aug; 55(15):6689-99. PubMed ID: 22632094
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D
    Reilly SW; Riad AA; Hsieh CJ; Sahlholm K; Jacome DA; Griffin S; Taylor M; Weng CC; Xu K; Kirschner N; Luedtke RR; Parry C; Malhotra S; Karanicolas J; Mach RH
    J Med Chem; 2019 May; 62(10):5132-5147. PubMed ID: 31021617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identifying Dopamine D3 Receptor Ligands through Virtual Screening and Exploring the Binding Modes of Hit Compounds.
    Jin H; Wu C; Su R; Sun T; Li X; Guo C
    Molecules; 2023 Jan; 28(2):. PubMed ID: 36677583
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the dopamine D3 receptor: an overview of drug design strategies.
    Cortés A; Moreno E; Rodríguez-Ruiz M; Canela EI; Casadó V
    Expert Opin Drug Discov; 2016 Jul; 11(7):641-64. PubMed ID: 27135354
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional Characterization of a Novel Series of Biased Signaling Dopamine D3 Receptor Agonists.
    Xu W; Wang X; Tocker AM; Huang P; Reith ME; Liu-Chen LY; Smith AB; Kortagere S
    ACS Chem Neurosci; 2017 Mar; 8(3):486-500. PubMed ID: 27801563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand.
    Mistry SN; Shonberg J; Draper-Joyce CJ; Klein Herenbrink C; Michino M; Shi L; Christopoulos A; Capuano B; Scammells PJ; Lane JR
    J Med Chem; 2015 Sep; 58(17):6819-43. PubMed ID: 26258690
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.
    Southern C; Cook JM; Neetoo-Isseljee Z; Taylor DL; Kettleborough CA; Merritt A; Bassoni DL; Raab WJ; Quinn E; Wehrman TS; Davenport AP; Brown AJ; Green A; Wigglesworth MJ; Rees S
    J Biomol Screen; 2013 Jun; 18(5):599-609. PubMed ID: 23396314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel roles for β-arrestins in the regulation of pharmacological sequestration to predict agonist-induced desensitization of dopamine D3 receptors.
    Min C; Zheng M; Zhang X; Caron MG; Kim KM
    Br J Pharmacol; 2013 Nov; 170(5):1112-29. PubMed ID: 23992580
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor.
    Burford NT; Clark MJ; Wehrman TS; Gerritz SW; Banks M; O'Connell J; Traynor JR; Alt A
    Proc Natl Acad Sci U S A; 2013 Jun; 110(26):10830-5. PubMed ID: 23754417
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods.
    Hsieh CJ; Riad A; Lee JY; Sahlholm K; Xu K; Luedtke RR; Mach RH
    Biomolecules; 2021 Apr; 11(4):. PubMed ID: 33918451
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.