These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 24021284)

  • 1. Mutant γPKC that causes spinocerebellar ataxia type 14 upregulates Hsp70, which protects cells from the mutant's cytotoxicity.
    Ogawa K; Seki T; Onji T; Adachi N; Tanaka S; Hide I; Saito N; Sakai N
    Biochem Biophys Res Commun; 2013 Oct; 440(1):25-30. PubMed ID: 24021284
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Congo red, an amyloid-inhibiting compound, alleviates various types of cellular dysfunction triggered by mutant protein kinase cγ that causes spinocerebellar ataxia type 14 (SCA14) by inhibiting oligomerization and aggregation.
    Seki T; Takahashi H; Yamamoto K; Ogawa K; Onji T; Adachi N; Tanaka S; Hide I; Saito N; Sakai N
    J Pharmacol Sci; 2010; 114(2):206-16. PubMed ID: 20938103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant gammaPKC found in spinocerebellar ataxia type 14 induces aggregate-independent maldevelopment of dendrites in primary cultured Purkinje cells.
    Seki T; Shimahara T; Yamamoto K; Abe N; Amano T; Adachi N; Takahashi H; Kashiwagi K; Saito N; Sakai N
    Neurobiol Dis; 2009 Feb; 33(2):260-73. PubMed ID: 19041943
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular pathophysiology of neurodegenerative disease caused by γPKC mutations.
    Sakai N; Saito N; Seki T
    World J Biol Psychiatry; 2011 Sep; 12 Suppl 1():95-8. PubMed ID: 21906004
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy.
    Yamamoto K; Seki T; Adachi N; Takahashi T; Tanaka S; Hide I; Saito N; Sakai N
    Genes Cells; 2010 May; 15(5):425-38. PubMed ID: 20398063
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutant protein kinase Cgamma found in spinocerebellar ataxia type 14 is susceptible to aggregation and causes cell death.
    Seki T; Adachi N; Ono Y; Mochizuki H; Hiramoto K; Amano T; Matsubayashi H; Matsumoto M; Kawakami H; Saito N; Sakai N
    J Biol Chem; 2005 Aug; 280(32):29096-106. PubMed ID: 15964845
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of trehalose on the properties of mutant {gamma}PKC, which causes spinocerebellar ataxia type 14, in neuronal cell lines and cultured Purkinje cells.
    Seki T; Abe-Seki N; Kikawada T; Takahashi H; Yamamoto K; Adachi N; Tanaka S; Hide I; Saito N; Sakai N
    J Biol Chem; 2010 Oct; 285(43):33252-33264. PubMed ID: 20705605
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological induction of heat shock proteins ameliorates toxicity of mutant PKCγ in spinocerebellar ataxia type 14.
    Nakazono A; Adachi N; Takahashi H; Seki T; Hamada D; Ueyama T; Sakai N; Saito N
    J Biol Chem; 2018 Sep; 293(38):14758-14774. PubMed ID: 30093405
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elucidation of the molecular mechanism and exploration of novel therapeutics for spinocerebellar ataxia caused by mutant protein kinase Cγ.
    Seki T; Adachi N; Abe-Seki N; Shimahara T; Takahashi H; Yamamoto K; Saito N; Sakai N
    J Pharmacol Sci; 2011; 116(3):239-47. PubMed ID: 21666345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. R659S mutation of gammaPKC is susceptible to cell death: implication of this mutation/polymorphism in the pathogenesis of retinitis pigmentosa.
    Mochizuki H; Seki T; Adachi N; Saito N; Mishima HK; Sakai N
    Neurochem Int; 2006 Dec; 49(7):669-75. PubMed ID: 16828200
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Deregulation of the actin cytoskeleton and macropinocytosis in response to phorbol ester by the mutant protein kinase C gamma that causes spinocerebellar ataxia type 14.
    Yamamoto K; Seki T; Yamamoto H; Adachi N; Tanaka S; Hide I; Saito N; Sakai N
    Front Physiol; 2014; 5():126. PubMed ID: 24744737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-hypoxia effect of adenovirus-mediated expression of heat shock protein 70 (HSP70) on primary cultured neurons.
    Hu D; Chen F; Guan C; Yang F; Qu Y
    J Neurosci Res; 2013 Sep; 91(9):1174-82. PubMed ID: 23686726
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aggregate formation of mutant protein kinase C gamma found in spinocerebellar ataxia type 14 impairs ubiquitin-proteasome system and induces endoplasmic reticulum stress.
    Seki T; Takahashi H; Adachi N; Abe N; Shimahara T; Saito N; Sakai N
    Eur J Neurosci; 2007 Dec; 26(11):3126-40. PubMed ID: 18005063
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7.
    Tsai HF; Lin SJ; Li C; Hsieh M
    Biochem Biophys Res Commun; 2005 Sep; 334(4):1279-86. PubMed ID: 16039988
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Upregulation of iHsp70 by mild heat shock protects rabbit myogenic stem cells: involvement of JNK signalling and c-Jun.
    Bironaite D; Pivoriunas A; Venalis A
    Cell Biol Int; 2012; 36(12):1089-96. PubMed ID: 22946646
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of HSP70 expression and recruitment of HSC70 and HSP70 in the nucleus reduce aggregation of a polyalanine expansion mutant of PABPN1 in HeLa cells.
    Wang Q; Mosser DD; Bag J
    Hum Mol Genet; 2005 Dec; 14(23):3673-84. PubMed ID: 16239242
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and characterization of PKCγ, a kinase associated with SCA14, as an amyloidogenic protein.
    Takahashi H; Adachi N; Shirafuji T; Danno S; Ueyama T; Vendruscolo M; Shuvaev AN; Sugimoto T; Seki T; Hamada D; Irie K; Hirai H; Sakai N; Saito N
    Hum Mol Genet; 2015 Jan; 24(2):525-39. PubMed ID: 25217572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.
    Guo F; Rocha K; Bali P; Pranpat M; Fiskus W; Boyapalle S; Kumaraswamy S; Balasis M; Greedy B; Armitage ES; Lawrence N; Bhalla K
    Cancer Res; 2005 Nov; 65(22):10536-44. PubMed ID: 16288046
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spinocerebellar ataxia type 14.
    Chen DH; Raskind WH; Bird TD
    Handb Clin Neurol; 2012; 103():555-9. PubMed ID: 21827914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK), a novel Hsp90-client tyrosine kinase: down-regulation of NPM-ALK expression and tyrosine phosphorylation in ALK(+) CD30(+) lymphoma cells by the Hsp90 antagonist 17-allylamino,17-demethoxygeldanamycin.
    Bonvini P; Gastaldi T; Falini B; Rosolen A
    Cancer Res; 2002 Mar; 62(5):1559-66. PubMed ID: 11888936
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.