324 related articles for article (PubMed ID: 24025331)
1. A crystal structure of the dengue virus non-structural protein 5 (NS5) polymerase delineates interdomain amino acid residues that enhance its thermostability and de novo initiation activities.
Lim SP; Koh JH; Seh CC; Liew CW; Davidson AD; Chua LS; Chandrasekaran R; Cornvik TC; Shi PY; Lescar J
J Biol Chem; 2013 Oct; 288(43):31105-14. PubMed ID: 24025331
[TBL] [Abstract][Full Text] [Related]
2. NS5 from Dengue Virus Serotype 2 Can Adopt a Conformation Analogous to That of Its Zika Virus and Japanese Encephalitis Virus Homologues.
El Sahili A; Soh TS; Schiltz J; Gharbi-Ayachi A; Seh CC; Shi PY; Lim SP; Lescar J
J Virol; 2019 Dec; 94(1):. PubMed ID: 31597763
[TBL] [Abstract][Full Text] [Related]
3. Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies.
Arora R; Liew CW; Soh TS; Otoo DA; Seh CC; Yue K; Nilar S; Wang G; Yokokawa F; Noble CG; Chen YL; Shi PY; Lescar J; Smith TM; Benson TE; Lim SP
J Virol; 2020 Nov; 94(24):. PubMed ID: 32907977
[TBL] [Abstract][Full Text] [Related]
4. Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.
Klema VJ; Ye M; Hindupur A; Teramoto T; Gottipati K; Padmanabhan R; Choi KH
PLoS Pathog; 2016 Feb; 12(2):e1005451. PubMed ID: 26895240
[TBL] [Abstract][Full Text] [Related]
5. A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
Zhao Y; Soh TS; Zheng J; Chan KW; Phoo WW; Lee CC; Tay MY; Swaminathan K; Cornvik TC; Lim SP; Shi PY; Lescar J; Vasudevan SG; Luo D
PLoS Pathog; 2015 Mar; 11(3):e1004682. PubMed ID: 25775415
[TBL] [Abstract][Full Text] [Related]
6. Perturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongation.
Wu J; Lu G; Zhang B; Gong P
J Virol; 2015 Jan; 89(1):249-61. PubMed ID: 25320292
[TBL] [Abstract][Full Text] [Related]
7. Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Lim SP; Noble CG; Seh CC; Soh TS; El Sahili A; Chan GK; Lescar J; Arora R; Benson T; Nilar S; Manjunatha U; Wan KF; Dong H; Xie X; Shi PY; Yokokawa F
PLoS Pathog; 2016 Aug; 12(8):e1005737. PubMed ID: 27500641
[TBL] [Abstract][Full Text] [Related]
8. Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization.
Cheng CX; Tan MJA; Chan KWK; Choy MMJ; Roman N; Arnold DDR; Bifani AM; Kong SYZ; Bist P; Nath BK; Swarbrick CMD; Forwood JK; Vasudevan SG
ACS Infect Dis; 2024 Jun; 10(6):2047-2062. PubMed ID: 38811007
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5.
Malet H; Egloff MP; Selisko B; Butcher RE; Wright PJ; Roberts M; Gruez A; Sulzenbacher G; Vonrhein C; Bricogne G; Mackenzie JM; Khromykh AA; Davidson AD; Canard B
J Biol Chem; 2007 Apr; 282(14):10678-89. PubMed ID: 17287213
[TBL] [Abstract][Full Text] [Related]
10. The crystal structure of Zika virus NS5 reveals conserved drug targets.
Duan W; Song H; Wang H; Chai Y; Su C; Qi J; Shi Y; Gao GF
EMBO J; 2017 Apr; 36(7):919-933. PubMed ID: 28254839
[TBL] [Abstract][Full Text] [Related]
11. Serotype-specific interactions among functional domains of dengue virus 2 nonstructural proteins (NS) 5 and NS3 are crucial for viral RNA replication.
Teramoto T; Balasubramanian A; Choi KH; Padmanabhan R
J Biol Chem; 2017 Jun; 292(23):9465-9479. PubMed ID: 28396347
[TBL] [Abstract][Full Text] [Related]
12. Identification of the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3.
Subramanian Manimekalai MS; Saw WG; Pan A; Grüber A; Grüber G
Acta Crystallogr D Struct Biol; 2016 Jun; 72(Pt 6):795-807. PubMed ID: 27303800
[TBL] [Abstract][Full Text] [Related]
13. Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
Gharbi-Ayachi A; Santhanakrishnan S; Wong YH; Chan KWK; Tan ST; Bates RW; Vasudevan SG; El Sahili A; Lescar J
J Virol; 2020 Oct; 94(21):. PubMed ID: 32796069
[TBL] [Abstract][Full Text] [Related]
14. The F1 motif of dengue virus polymerase NS5 is involved in promoter-dependent RNA synthesis.
Iglesias NG; Filomatori CV; Gamarnik AV
J Virol; 2011 Jun; 85(12):5745-56. PubMed ID: 21471248
[TBL] [Abstract][Full Text] [Related]
15. Optimal flexibility of the linker region of Zika virus NS5 methyltransferase-polymerase is critical for virus replication.
Flory C; Chan KWK; Bifani AM; Choy MMJ; Lescar J; Ooi EE; Tautz N; Vasudevan SG
Antiviral Res; 2021 Nov; 195():105194. PubMed ID: 34699863
[TBL] [Abstract][Full Text] [Related]
16. Crystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interface.
Lu G; Gong P
PLoS Pathog; 2013; 9(8):e1003549. PubMed ID: 23950717
[TBL] [Abstract][Full Text] [Related]
17. The dengue virus NS5 protein as a target for drug discovery.
Lim SP; Noble CG; Shi PY
Antiviral Res; 2015 Jul; 119():57-67. PubMed ID: 25912817
[TBL] [Abstract][Full Text] [Related]
18. Perspectives on the current antiviral developments towards RNA-dependent RNA polymerase (RdRp) and methyltransferase (MTase) domains of dengue virus non-structural protein 5 (DENV-NS5).
Sreekanth GP
Eur J Med Chem; 2023 Aug; 256():115416. PubMed ID: 37159959
[TBL] [Abstract][Full Text] [Related]
19. The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain.
Potisopon S; Priet S; Collet A; Decroly E; Canard B; Selisko B
Nucleic Acids Res; 2014 Oct; 42(18):11642-56. PubMed ID: 25209234
[TBL] [Abstract][Full Text] [Related]
20. Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening.
Niyomrattanakit P; Wan KF; Chung KY; Abas SN; Seh CC; Dong H; Lim CC; Chao AT; Lee CB; Nilar S; Lescar J; Shi PY; Beer D; Lim SP
Antiviral Res; 2015 Jul; 119():36-46. PubMed ID: 25896272
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]