These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency. Ring L; Neth P; Weber C; Steffens S; Faussner A Cell Signal; 2014 Feb; 26(2):260-7. PubMed ID: 24269653 [TBL] [Abstract][Full Text] [Related]
6. The Frizzled family of unconventional G-protein-coupled receptors. Schulte G; Bryja V Trends Pharmacol Sci; 2007 Oct; 28(10):518-25. PubMed ID: 17884187 [TBL] [Abstract][Full Text] [Related]
7. Frizzleds as GPCRs - More Conventional Than We Thought! Schulte G; Wright SC Trends Pharmacol Sci; 2018 Sep; 39(9):828-842. PubMed ID: 30049420 [TBL] [Abstract][Full Text] [Related]
8. Wnt Binding Affinity Prediction for Putative Frizzled-Type Cysteine-Rich Domains. Agostino M; Pohl SÖ Int J Mol Sci; 2019 Aug; 20(17):. PubMed ID: 31454915 [TBL] [Abstract][Full Text] [Related]
9. Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation. Bryja V; Cajánek L; Grahn A; Schulte G Acta Physiol (Oxf); 2007 May; 190(1):55-61. PubMed ID: 17428233 [TBL] [Abstract][Full Text] [Related]
10. Frizzleds and WNT/β-catenin signaling--The black box of ligand-receptor selectivity, complex stoichiometry and activation kinetics. Schulte G Eur J Pharmacol; 2015 Sep; 763(Pt B):191-5. PubMed ID: 26003275 [TBL] [Abstract][Full Text] [Related]
11. Frizzled homolog proteins, microRNAs and Wnt signaling in cancer. Ueno K; Hirata H; Hinoda Y; Dahiya R Int J Cancer; 2013 Apr; 132(8):1731-40. PubMed ID: 22833265 [TBL] [Abstract][Full Text] [Related]
12. Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs. Dijksterhuis JP; Baljinnyam B; Stanger K; Sercan HO; Ji Y; Andres O; Rubin JS; Hannoush RN; Schulte G J Biol Chem; 2015 Mar; 290(11):6789-98. PubMed ID: 25605717 [TBL] [Abstract][Full Text] [Related]
13. WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins. Bowin CF; Inoue A; Schulte G J Biol Chem; 2019 Aug; 294(31):11677-11684. PubMed ID: 31235524 [TBL] [Abstract][Full Text] [Related]
14. Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment. Valnohova J; Kowalski-Jahn M; Sunahara RK; Schulte G J Biol Chem; 2018 Nov; 293(46):17875-17887. PubMed ID: 30237173 [TBL] [Abstract][Full Text] [Related]
15. Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway. Hua Y; Yang Y; Li Q; He X; Zhu W; Wang J; Gan X J Biol Chem; 2018 Dec; 293(51):19710-19724. PubMed ID: 30361437 [TBL] [Abstract][Full Text] [Related]
16. Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling. Janda CY; Dang LT; You C; Chang J; de Lau W; Zhong ZA; Yan KS; Marecic O; Siepe D; Li X; Moody JD; Williams BO; Clevers H; Piehler J; Baker D; Kuo CJ; Garcia KC Nature; 2017 May; 545(7653):234-237. PubMed ID: 28467818 [TBL] [Abstract][Full Text] [Related]
17. Deconvolution of WNT-induced Frizzled conformational dynamics with fluorescent biosensors. Schihada H; Kowalski-Jahn M; Turku A; Schulte G Biosens Bioelectron; 2021 Apr; 177():112948. PubMed ID: 33486136 [TBL] [Abstract][Full Text] [Related]
18. Yellow submarine of the Wnt/Frizzled signaling: submerging from the G protein harbor to the targets. Koval A; Purvanov V; Egger-Adam D; Katanaev VL Biochem Pharmacol; 2011 Nov; 82(10):1311-9. PubMed ID: 21689640 [TBL] [Abstract][Full Text] [Related]