BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 24036541)

  • 1. The CDK-activating kinase Cdk7: taking yes for an answer.
    Schachter MM; Fisher RP
    Cell Cycle; 2013 Oct; 12(20):3239-40. PubMed ID: 24036541
    [No Abstract]   [Full Text] [Related]  

  • 2. CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.
    Bisteau X; Paternot S; Colleoni B; Ecker K; Coulonval K; De Groote P; Declercq W; Hengst L; Roger PP
    PLoS Genet; 2013 May; 9(5):e1003546. PubMed ID: 23737759
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression.
    Schachter MM; Merrick KA; Larochelle S; Hirschi A; Zhang C; Shokat KM; Rubin SM; Fisher RP
    Mol Cell; 2013 Apr; 50(2):250-60. PubMed ID: 23622515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.
    Bockstaele L; Bisteau X; Paternot S; Roger PP
    Mol Cell Biol; 2009 Aug; 29(15):4188-200. PubMed ID: 19487459
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rb inactivation in cell cycle and cancer: the puzzle of highly regulated activating phosphorylation of CDK4 versus constitutively active CDK-activating kinase.
    Paternot S; Bockstaele L; Bisteau X; Kooken H; Coulonval K; Roger PP
    Cell Cycle; 2010 Feb; 9(4):689-99. PubMed ID: 20107323
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.
    Larochelle S; Merrick KA; Terret ME; Wohlbold L; Barboza NM; Zhang C; Shokat KM; Jallepalli PV; Fisher RP
    Mol Cell; 2007 Mar; 25(6):839-50. PubMed ID: 17386261
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lower cyclin H and cyclin-dependent kinase-activating kinase activity in cell cycle arrest induced by lack of adhesion to substratum.
    Solorzano L; Rieber MS; Rieber M
    Cancer Res; 2000 Dec; 60(24):7114-8. PubMed ID: 11156419
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.
    Garrett S; Barton WA; Knights R; Jin P; Morgan DO; Fisher RP
    Mol Cell Biol; 2001 Jan; 21(1):88-99. PubMed ID: 11113184
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proto-oncogene c-myc acts through the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) to facilitate the activation of Cdk4/6 and early G(1) phase progression.
    Obaya AJ; Kotenko I; Cole MD; Sedivy JM
    J Biol Chem; 2002 Aug; 277(34):31263-9. PubMed ID: 12070150
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.
    Larochelle S; Batliner J; Gamble MJ; Barboza NM; Kraybill BC; Blethrow JD; Shokat KM; Fisher RP
    Nat Struct Mol Biol; 2006 Jan; 13(1):55-62. PubMed ID: 16327805
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.
    Ray A; James MK; Larochelle S; Fisher RP; Blain SW
    Mol Cell Biol; 2009 Feb; 29(4):986-99. PubMed ID: 19075005
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
    Ruan C; Wang C; Gong X; Zhang Y; Deng W; Zhou J; Huang D; Wang Z; Zhang Q; Guo A; Lu J; Gao J; Peng D; Xue Y
    Autophagy; 2021 Jun; 17(6):1426-1447. PubMed ID: 32397800
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Is Cdk7/cyclin H/MAT1 the genuine cdk activating kinase in cycling Xenopus egg extracts?
    Fesquet D; Morin N; Doree M; Devault A
    Oncogene; 1997 Sep; 15(11):1303-7. PubMed ID: 9315098
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of CAK kinase activity by p53.
    Schneider E; Montenarh M; Wagner P
    Oncogene; 1998 Nov; 17(21):2733-41. PubMed ID: 9840937
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Complex mechanisms underlying impaired activation of Cdk4 and Cdk2 in replicative senescence: roles of p16, p21, and cyclin D1.
    Morisaki H; Ando A; Nagata Y; Pereira-Smith O; Smith JR; Ikeda K; Nakanishi M
    Exp Cell Res; 1999 Dec; 253(2):503-10. PubMed ID: 10585273
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CAK-Cyclin-dependent Activating Kinase: a key kinase in cell cycle control and a target for drugs?
    Lolli G; Johnson LN
    Cell Cycle; 2005 Apr; 4(4):572-7. PubMed ID: 15876871
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Changes in cyclin dependent kinase expression and activity accompanying lens fiber cell differentiation.
    Gao CY; Rampalli AM; Cai HC; He HY; Zelenka PS
    Exp Eye Res; 1999 Dec; 69(6):695-703. PubMed ID: 10620399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells.
    Merrick KA; Larochelle S; Zhang C; Allen JJ; Shokat KM; Fisher RP
    Mol Cell; 2008 Dec; 32(5):662-72. PubMed ID: 19061641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity.
    Wohlbold L; Larochelle S; Liao JC; Livshits G; Singer J; Shokat KM; Fisher RP
    Cell Cycle; 2006 Mar; 5(5):546-54. PubMed ID: 16552187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cdc2 activation in fission yeast depends on Mcs6 and Csk1, two partially redundant Cdk-activating kinases (CAKs).
    Lee KM; Saiz JE; Barton WA; Fisher RP
    Curr Biol; 1999 Apr; 9(8):441-4. PubMed ID: 10226032
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.