BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 24038521)

  • 1. Loss of p53 cooperates with K-ras activation to induce glioma formation in a region-independent manner.
    Muñoz DM; Tung T; Agnihotri S; Singh S; Guha A; Zadeh G; Hawkins C
    Glia; 2013 Nov; 61(11):1862-72. PubMed ID: 24038521
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
    Uhrbom L; Dai C; Celestino JC; Rosenblum MK; Fuller GN; Holland EC
    Cancer Res; 2002 Oct; 62(19):5551-8. PubMed ID: 12359767
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.
    Uhrbom L; Kastemar M; Johansson FK; Westermark B; Holland EC
    Cancer Res; 2005 Mar; 65(6):2065-9. PubMed ID: 15781613
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.
    Gil-Perotin S; Marin-Husstege M; Li J; Soriano-Navarro M; Zindy F; Roussel MF; Garcia-Verdugo JM; Casaccia-Bonnefil P
    J Neurosci; 2006 Jan; 26(4):1107-16. PubMed ID: 16436596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of p53 Concurrent with RAS and TERT Activation Induces Glioma Formation.
    Gong M; Fan X; Yu H; Niu W; Sun S; Wang H; Chen X
    Mol Neurobiol; 2023 Jun; 60(6):3452-3463. PubMed ID: 36867344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma.
    Abel TW; Clark C; Bierie B; Chytil A; Aakre M; Gorska A; Moses HL
    Mol Cancer Res; 2009 May; 7(5):645-53. PubMed ID: 19435821
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells.
    Bartesaghi S; Graziano V; Galavotti S; Henriquez NV; Betts J; Saxena J; Minieri V; A D; Karlsson A; Martins LM; Capasso M; Nicotera P; Brandner S; De Laurenzi V; Salomoni P
    Proc Natl Acad Sci U S A; 2015 Jan; 112(4):1059-64. PubMed ID: 25583481
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss-Induced Gliomagenesis and Harbor Specific Therapeutic Vulnerabilities.
    Verma R; Chen X; Xin D; Luo Z; Ogurek S; Xin M; Rao R; Berry K; Lu QR
    Cancer Res; 2023 Mar; 83(6):890-905. PubMed ID: 36634201
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation.
    Lee JS; Lee HJ; Moon BH; Song SH; Lee MO; Shim SH; Kim HS; Lee MC; Kwon JT; Fornace AJ; Kim SU; Cha HJ
    Stem Cell Rev Rep; 2012 Jun; 8(2):532-45. PubMed ID: 21755312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic alterations in brain tumors following 1,3-butadiene exposure in B6C3F1 mice.
    Kim Y; Hong HH; Lachat Y; Clayton NP; Devereux TR; Melnick RL; Hegi ME; Sills RC
    Toxicol Pathol; 2005; 33(3):307-12. PubMed ID: 15814359
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis.
    Ji P; Zhou X; Liu Q; Fuller GN; Phillips LM; Zhang W
    Oncotarget; 2016 Apr; 7(17):23521-9. PubMed ID: 26993778
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation.
    Solga AC; Toonen JA; Pan Y; Cimino PJ; Ma Y; Castillon GA; Gianino SM; Ellisman MH; Lee DY; Gutmann DH
    Oncotarget; 2017 Jul; 8(29):47206-47215. PubMed ID: 28525381
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conditional expression of K-ras in an epithelial compartment that includes the stem cells is sufficient to promote squamous cell carcinogenesis.
    Vitale-Cross L; Amornphimoltham P; Fisher G; Molinolo AA; Gutkind JS
    Cancer Res; 2004 Dec; 64(24):8804-7. PubMed ID: 15604235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Brain cancer stem-like cell genesis from p53-deficient mouse astrocytes by oncogenic Ras.
    Lee JS; Gil JE; Kim JH; Kim TK; Jin X; Oh SY; Sohn YW; Jeon HM; Park HJ; Park JW; Shin YJ; Chung YG; Lee JB; You S; Kim H
    Biochem Biophys Res Commun; 2008 Jan; 365(3):496-502. PubMed ID: 18021740
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.
    Tuveson DA; Shaw AT; Willis NA; Silver DP; Jackson EL; Chang S; Mercer KL; Grochow R; Hock H; Crowley D; Hingorani SR; Zaks T; King C; Jacobetz MA; Wang L; Bronson RT; Orkin SH; DePinho RA; Jacks T
    Cancer Cell; 2004 Apr; 5(4):375-87. PubMed ID: 15093544
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.
    Gonzalez PP; Kim J; Galvao RP; Cruickshanks N; Abounader R; Zong H
    Glia; 2018 May; 66(5):999-1015. PubMed ID: 29392777
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential transformation capacity of neuro-glial progenitors during development.
    Muñoz DM; Singh S; Tung T; Agnihotri S; Nagy A; Guha A; Zadeh G; Hawkins C
    Proc Natl Acad Sci U S A; 2013 Aug; 110(35):14378-83. PubMed ID: 23942126
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.
    Caulin C; Nguyen T; Lang GA; Goepfert TM; Brinkley BR; Cai WW; Lozano G; Roop DR
    J Clin Invest; 2007 Jul; 117(7):1893-901. PubMed ID: 17607363
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Knock-in of mutant K-ras in nontumorigenic human epithelial cells as a new model for studying K-ras mediated transformation.
    Konishi H; Karakas B; Abukhdeir AM; Lauring J; Gustin JP; Garay JP; Konishi Y; Gallmeier E; Bachman KE; Park BH
    Cancer Res; 2007 Sep; 67(18):8460-7. PubMed ID: 17875684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells.
    Kurtsdotter I; Topcic D; Karlén A; Singla B; Hagey DW; Bergsland M; Siesjö P; Nistér M; Carlson JW; Lefebvre V; Persson O; Holmberg J; Muhr J
    Cancer Res; 2017 Sep; 77(18):4985-4997. PubMed ID: 28687615
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.