188 related articles for article (PubMed ID: 24039134)
1. Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.
Kim J; Kim Y; Tae J; Yeom M; Moon B; Huang XP; Roth BL; Lee K; Rhim H; Choo IH; Chong Y; Keum G; Nam G; Choo H
ChemMedChem; 2013 Nov; 8(11):1855-64. PubMed ID: 24039134
[TBL] [Abstract][Full Text] [Related]
2. Discovery of aryl-biphenyl-2-ylmethylpiperazines as novel scaffolds for 5-HT(7) ligands and role of the aromatic substituents in binding to the target receptor.
Kim Y; Kim J; Tae J; Roth BL; Rhim H; Keum G; Nam G; Choo H
Bioorg Med Chem; 2013 May; 21(9):2568-76. PubMed ID: 23541835
[TBL] [Abstract][Full Text] [Related]
3. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Niso M; Perrone R; Tortorella V
J Med Chem; 2004 Dec; 47(26):6616-24. PubMed ID: 15588097
[TBL] [Abstract][Full Text] [Related]
4. Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.
Lacivita E; Patarnello D; Stroth N; Caroli A; Niso M; Contino M; De Giorgio P; Di Pilato P; Colabufo NA; Berardi F; Perrone R; Svenningsson P; Hedlund PB; Leopoldo M
J Med Chem; 2012 Jul; 55(14):6375-80. PubMed ID: 22738316
[TBL] [Abstract][Full Text] [Related]
5. Sulfonamides with the N-alkyl-N'-dialkylguanidine moiety as 5-HT7 receptor ligands.
Zajdel P; Subra G; Verdie P; Gabzdyl E; Bojarski AJ; Duszyńska B; Martinez J; Pawłowski M
Bioorg Med Chem Lett; 2009 Aug; 19(16):4827-31. PubMed ID: 19560916
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.
Shimoda Y; Yui J; Xie L; Fujinaga M; Yamasaki T; Ogawa M; Nengaki N; Kumata K; Hatori A; Kawamura K; Zhang MR
Bioorg Med Chem; 2013 Sep; 21(17):5316-22. PubMed ID: 23830697
[TBL] [Abstract][Full Text] [Related]
7. Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord.
Dogrul A; Seyrek M
Br J Pharmacol; 2006 Nov; 149(5):498-505. PubMed ID: 16921395
[TBL] [Abstract][Full Text] [Related]
8. Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors.
Mahé C; Loetscher E; Feuerbach D; Müller W; Seiler MP; Schoeffter P
Eur J Pharmacol; 2004 Jul; 495(2-3):97-102. PubMed ID: 15249157
[TBL] [Abstract][Full Text] [Related]
9. Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719.
Thomas DR; Gittins SA; Collin LL; Middlemiss DN; Riley G; Hagan J; Gloger I; Ellis CE; Forbes IT; Brown AM
Br J Pharmacol; 1998 Jul; 124(6):1300-6. PubMed ID: 9720804
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of novel series of 5-HT6 receptor ligands having indole, a central aromatic core and 1-amino-4 methyl piperazine as a positive ionizable group.
Hayat F; Cho S; Rhim H; Indu Viswanath AN; Pae AN; Lee JY; Choo DJ; Choo HY
Bioorg Med Chem; 2013 Sep; 21(17):5573-82. PubMed ID: 23810425
[TBL] [Abstract][Full Text] [Related]
11. Towards metabolically stable 5-HT7 receptor ligands: a study on 1-arylpiperazine derivatives and related isosters.
Lacivita E; De Giorgio P; Patarnello D; Niso M; Colabufo NA; Berardi F; Perrone R; Satala G; Duszynska B; Bojarski AJ; Leopoldo M
Exp Brain Res; 2013 Oct; 230(4):569-82. PubMed ID: 23571499
[TBL] [Abstract][Full Text] [Related]
12. New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.
Liao Y; Böttcher H; Harting J; Greiner H; van Amsterdam C; Cremers T; Sundell S; März J; Rautenberg W; Wikström H
J Med Chem; 2000 Feb; 43(3):517-25. PubMed ID: 10669578
[TBL] [Abstract][Full Text] [Related]
13. New 1-arylindoles based serotonin 5-HT7 antagonists. Synthesis and binding evaluation studies.
Sagnes C; Fournet G; Satala G; Bojarski AJ; Joseph B
Eur J Med Chem; 2014 Mar; 75():159-68. PubMed ID: 24531229
[TBL] [Abstract][Full Text] [Related]
14. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
[TBL] [Abstract][Full Text] [Related]
15. 5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity.
Kim Y; Park H; Lee J; Tae J; Kim HJ; Min SJ; Rhim H; Choo H
Eur J Med Chem; 2016 Nov; 123():180-190. PubMed ID: 27475109
[TBL] [Abstract][Full Text] [Related]
16. Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.
Intagliata S; Modica MN; Pittalà V; Salerno L; Siracusa MA; Cagnotto A; Salmona M; Romeo G
Bioorg Med Chem Lett; 2016 Aug; 26(16):4052-6. PubMed ID: 27396505
[TBL] [Abstract][Full Text] [Related]
17. Indole-3-piperazinyl derivatives: novel chemical class of 5-HT(6) receptor antagonists.
Nirogi RV; Deshpande AD; Kambhampati R; Badange RK; Kota L; Daulatabad AV; Shinde AK; Ahmad I; Kandikere V; Jayarajan P; Dubey PK
Bioorg Med Chem Lett; 2011 Jan; 21(1):346-9. PubMed ID: 21134749
[TBL] [Abstract][Full Text] [Related]
18. Serotonin induces peripheral mechanical antihyperalgesic effects in mice.
Diniz DA; Petrocchi JA; Navarro LC; Souza TC; Castor MG; Perez AC; Duarte ID; Romero TR
Eur J Pharmacol; 2015 Nov; 767():94-7. PubMed ID: 26460149
[TBL] [Abstract][Full Text] [Related]
19. Novel 5-HT7 receptor inverse agonists. Synthesis and molecular modeling of arylpiperazine- and 1,2,3,4-tetrahydroisoquinoline-based arylsulfonamides.
Vermeulen ES; van Smeden M; Schmidt AW; Sprouse JS; Wikström HV; Grol CJ
J Med Chem; 2004 Oct; 47(22):5451-66. PubMed ID: 15481983
[TBL] [Abstract][Full Text] [Related]
20. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
Cappelli A; Anzini M; Vomero S; Canullo L; Mennuni L; Makovec F; Doucet E; Hamon M; Menziani MC; De Benedetti PG; Bruni G; Romeo MR; Giorgi G; Donati A
J Med Chem; 1999 May; 42(9):1556-75. PubMed ID: 10229626
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
