BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 24039728)

  • 1. Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines.
    Visagie M; Theron A; Mqoco T; Vieira W; Prudent R; Martinez A; Lafanechère L; Joubert A
    PLoS One; 2013; 8(9):e71935. PubMed ID: 24039728
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells.
    Visagie MH; Jaiswal SR; Joubert AM
    Biol Res; 2016 Nov; 49(1):43. PubMed ID: 27806731
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198.
    LaVallee TM; Burke PA; Swartz GM; Hamel E; Agoston GE; Shah J; Suwandi L; Hanson AD; Fogler WE; Sidor CF; Treston AM
    Mol Cancer Ther; 2008 Jun; 7(6):1472-82. PubMed ID: 18566218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
    Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
    Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-methoxyestradiol inhibits the anaphase-promoting complex and protein translation in human breast cancer cells.
    Bhati R; Gökmen-Polar Y; Sledge GW; Fan C; Nakshatri H; Ketelsen D; Borchers CH; Dial MJ; Patterson C; Klauber-DeMore N
    Cancer Res; 2007 Jan; 67(2):702-8. PubMed ID: 17234781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.
    Theron A; Prudent R; Nolte E; van den Bout I; Punchoo R; Marais S; du Toit P; Hlophe Y; van Papendorp D; Lafanechère L; Joubert A
    Cancer Chemother Pharmacol; 2015 Feb; 75(2):431-7. PubMed ID: 25547405
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel 2-methoxyestradiol analogues with antitumor activity.
    Tinley TL; Leal RM; Randall-Hlubek DA; Cessac JW; Wilkens LR; Rao PN; Mooberry SL
    Cancer Res; 2003 Apr; 63(7):1538-49. PubMed ID: 12670902
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro changes in mitochondrial potential, aggresome formation and caspase activity by a novel 17-β-estradiol analogue in breast adenocarcinoma cells.
    Nkandeu DS; Mqoco TV; Visagie MH; Stander BA; Wolmarans E; Cronje MJ; Joubert AM
    Cell Biochem Funct; 2013 Oct; 31(7):566-74. PubMed ID: 23307628
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.
    Kamal A; Kumar GB; Vishnuvardhan MV; Shaik AB; Reddy VS; Mahesh R; Sayeeda IB; Kapure JS
    Org Biomol Chem; 2015 Apr; 13(13):3963-81. PubMed ID: 25721862
    [TBL] [Abstract][Full Text] [Related]  

  • 10. beta-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells.
    Gökmen-Polar Y; Escuin D; Walls CD; Soule SE; Wang Y; Sanders KL; Lavallee TM; Wang M; Guenther BD; Giannakakou P; Sledge GW
    Cancer Res; 2005 Oct; 65(20):9406-14. PubMed ID: 16230404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity.
    Chua YS; Chua YL; Hagen T
    Mol Cancer Ther; 2010 Jan; 9(1):224-35. PubMed ID: 20053769
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The hematopoietic-specific beta1-tubulin is naturally resistant to 2-methoxyestradiol and protects patients from drug-induced myelosuppression.
    Escuin D; Burke PA; McMahon-Tobin G; Hembrough T; Wang Y; Alcaraz AA; Leandro-García LJ; Rodríguez-Antona C; Snyder JP; Lavallee TM; Giannakakou P
    Cell Cycle; 2009 Dec; 8(23):3914-24. PubMed ID: 19901556
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The in vitro effects of 2-methoxyestradiol-bis-sulphamate on cell numbers, membrane integrity and cell morphology, and the possible induction of apoptosis and autophagy in a non-tumorigenic breast epithelial cell line.
    Visagie MH; Joubert AM
    Cell Mol Biol Lett; 2010 Dec; 15(4):564-81. PubMed ID: 20697831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell lines.
    Visagie MH; Birkholtz LM; Joubert AM
    Cell Biosci; 2015; 5():19. PubMed ID: 25908963
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition.
    Padmaja P; Koteswara Rao G; Indrasena A; Subba Reddy BV; Patel N; Shaik AB; Reddy N; Dubey PK; Bhadra MP
    Org Biomol Chem; 2015 Feb; 13(5):1404-14. PubMed ID: 25467166
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2-Methoxymethylestradiol: a new 2-methoxy estrogen analog that exhibits antiproliferative activity and alters tubulin dynamics.
    Brueggemeier RW; Bhat AS; Lovely CJ; Coughenour HD; Joomprabutra S; Weitzel DH; Vandre DD; Yusuf F; Burak WE
    J Steroid Biochem Mol Biol; 2001 Aug; 78(2):145-56. PubMed ID: 11566439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G; Cecconet L; Leszl A; Basso G; Brun P; Salvador A; Dall'Acqua F; Diana P; Barraja P; Cirrincione G
    Cancer Chemother Pharmacol; 2009 Nov; 64(6):1235-51. PubMed ID: 19363609
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway.
    Chiang NJ; Lin CI; Liou JP; Kuo CC; Chang CY; Chen LT; Chang JY
    PLoS One; 2013; 8(3):e58953. PubMed ID: 23554962
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors.
    Sri Ramya PV; Angapelly S; Guntuku L; Singh Digwal C; Nagendra Babu B; Naidu VGM; Kamal A
    Eur J Med Chem; 2017 Feb; 127():100-114. PubMed ID: 28038323
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, cytotoxic effects and tubulin polymerization inhibition of 1,4-disubstituted 1,2,3-triazole analogs of 2-methoxyestradiol.
    Solum EJ; Vik A; Hansen TV
    Steroids; 2014 Sep; 87():46-53. PubMed ID: 24923521
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.