BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 24039840)

  • 1. Integrin - dependent mechanotransduction in mechanically stimulated human annulus fibrosus cells: evidence for an alternative mechanotransduction pathway operating with degeneration.
    Gilbert HT; Nagra NS; Freemont AJ; Millward-Sadler SJ; Hoyland JA
    PLoS One; 2013; 8(9):e72994. PubMed ID: 24039840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration.
    Gilbert HT; Hoyland JA; Freemont AJ; Millward-Sadler SJ
    Arthritis Res Ther; 2011 Jan; 13(1):R8. PubMed ID: 21276216
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional impact of integrin α5β1 on the homeostasis of intervertebral discs: a study of mechanotransduction pathways using a novel dynamic loading organ culture system.
    Kurakawa T; Kakutani K; Morita Y; Kato Y; Yurube T; Hirata H; Miyazaki S; Terashima Y; Maeno K; Takada T; Doita M; Kurosaka M; Inoue N; Masuda K; Nishida K
    Spine J; 2015 Mar; 15(3):417-26. PubMed ID: 25546513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes.
    Minogue BM; Richardson SM; Zeef LA; Freemont AJ; Hoyland JA
    Arthritis Res Ther; 2010; 12(1):R22. PubMed ID: 20149220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs.
    Le Maitre CL; Frain J; Millward-Sadler J; Fotheringham AP; Freemont AJ; Hoyland JA
    Arthritis Rheum; 2009 Feb; 60(2):460-9. PubMed ID: 19180480
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Moderate mechanical stimulation rescues degenerative annulus fibrosus by suppressing caveolin-1 mediated pro-inflammatory signaling pathway.
    Zhang W; Wang H; Yuan Z; Chu G; Sun H; Yu Z; Liang H; Liu T; Zhou F; Li B
    Int J Biol Sci; 2021; 17(5):1395-1412. PubMed ID: 33867854
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Beta1 integrin inhibits apoptosis induced by cyclic stretch in annulus fibrosus cells via ERK1/2 MAPK pathway.
    Zhang K; Ding W; Sun W; Sun XJ; Xie YZ; Zhao CQ; Zhao J
    Apoptosis; 2016 Jan; 21(1):13-24. PubMed ID: 26467923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration.
    Melrose J; Shu C; Young C; Ho R; Smith MM; Young AA; Smith SS; Gooden B; Dart A; Podadera J; Appleyard RC; Little CB
    Spine (Phila Pa 1976); 2012 Jan; 37(1):18-25. PubMed ID: 22179320
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Angle-ply biomaterial scaffold for annulus fibrosus repair replicates native tissue mechanical properties, restores spinal kinematics, and supports cell viability.
    Borem R; Madeline A; Walters J; Mayo H; Gill S; Mercuri J
    Acta Biomater; 2017 Aug; 58():254-268. PubMed ID: 28587986
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclic tensile stress of human annulus fibrosus cells induces MAPK activation: involvement in proinflammatory gene expression.
    Pratsinis H; Papadopoulou A; Neidlinger-Wilke C; Brayda-Bruno M; Wilke HJ; Kletsas D
    Osteoarthritis Cartilage; 2016 Apr; 24(4):679-87. PubMed ID: 26687822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The mechano-response of murine annulus fibrosus cells to cyclic tensile strain is frequency dependent.
    Kim MKM; Burns MJ; Serjeant ME; Séguin CA
    JOR Spine; 2020 Dec; 3(4):e21114. PubMed ID: 33392464
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades.
    Stich S; Jagielski M; Fleischmann A; Meier C; Bussmann P; Kohl B; Schmidt J; Krüger JP; Endres M; Cabraja M; Reimann K; Laue D; Ertel W; Sittinger M
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32245213
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aging affects response to cyclic tensile stretch: paradigm for intervertebral disc degeneration.
    Cho H; Seth A; Warmbold J; Robertson JT; Hasty KA
    Eur Cell Mater; 2011 Sep; 22():137-45; discussion 145-6. PubMed ID: 21932191
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Three-dimensional development of tensile pre-strained annulus fibrosus cells for tissue regeneration: an in-vitro study.
    Chuah YJ; Lee WC; Wong HK; Kang Y; Hee HT
    Exp Cell Res; 2015 Feb; 331(1):176-182. PubMed ID: 25261779
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Degenerate intervertebral disc-like pH induces a catabolic mechanoresponse in human nucleus pulposus cells.
    Hodson NW; Patel S; Richardson SM; Hoyland JA; Gilbert HTJ
    JOR Spine; 2018 Mar; 1(1):e1004. PubMed ID: 31463436
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transient receptor potential vanilloid 4 regulates extracellular matrix composition and mediates load-induced intervertebral disc degeneration in a mouse model.
    Mark Kim MK; Lawrence M; Quinonez D; Brooks C; Ramachandran R; Séguin CA
    Osteoarthritis Cartilage; 2024 Jul; 32(7):881-894. PubMed ID: 38604493
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Annulus fibrosus cells can induce mineralization: an in vitro study.
    Nosikova Y; Santerre JP; Grynpas MD; Kandel RA
    Spine J; 2013 Apr; 13(4):443-53. PubMed ID: 23332388
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human cells derived from degenerate intervertebral discs respond differently to those derived from non-degenerate intervertebral discs following application of dynamic hydrostatic pressure.
    Le Maitre CL; Frain J; Fotheringham AP; Freemont AJ; Hoyland JA
    Biorheology; 2008; 45(5):563-75. PubMed ID: 19065005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Decellularized Intervertebral Discs: A Potential Replacement for Degenerate Human Discs.
    Norbertczak HT; Ingham E; Fermor HL; Wilcox RK
    Tissue Eng Part C Methods; 2020 Nov; 26(11):565-576. PubMed ID: 33050844
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc.
    Tolofari SK; Richardson SM; Freemont AJ; Hoyland JA
    Arthritis Res Ther; 2010; 12(1):R1. PubMed ID: 20051117
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.