178 related articles for article (PubMed ID: 24040362)
1. A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.
Zins K; Lucas T; Reichl P; Abraham D; Aharinejad S
PLoS One; 2013; 8(9):e74924. PubMed ID: 24040362
[TBL] [Abstract][Full Text] [Related]
2. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor.
Gao Y; Dickerson JB; Guo F; Zheng J; Zheng Y
Proc Natl Acad Sci U S A; 2004 May; 101(20):7618-23. PubMed ID: 15128949
[TBL] [Abstract][Full Text] [Related]
3. Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42.
Kücük P; Abbey L; Schmitt J; Henninger C; Fritz G
Pharmacol Res; 2024 May; 203():107165. PubMed ID: 38561112
[TBL] [Abstract][Full Text] [Related]
4. The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo.
Grimes MM; Kenney SR; Dominguez DR; Brayer KJ; Guo Y; Wandinger-Ness A; Hudson LG
BMC Cancer; 2021 Jan; 21(1):40. PubMed ID: 33413202
[TBL] [Abstract][Full Text] [Related]
5. Activation of Rac1 is closely related to androgen-independent cell proliferation of prostate cancer cells both in vitro and in vivo.
Kobayashi T; Inoue T; Shimizu Y; Terada N; Maeno A; Kajita Y; Yamasaki T; Kamba T; Toda Y; Mikami Y; Yamada T; Kamoto T; Ogawa O; Nakamura E
Mol Endocrinol; 2010 Apr; 24(4):722-34. PubMed ID: 20203103
[TBL] [Abstract][Full Text] [Related]
6. Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Floerchinger A; Murphy KJ; Latham SL; Warren SC; McCulloch AT; Lee YK; Stoehr J; Mélénec P; Guaman CS; Metcalf XL; Lee V; Zaratzian A; Da Silva A; Tayao M; Rolo S; Phimmachanh M; Sultani G; McDonald L; Mason SM; Ferrari N; Ooms LM; Johnsson AE; Spence HJ; Olson MF; Machesky LM; Sansom OJ; Morton JP; Mitchell CA; Samuel MS; Croucher DR; Welch HCE; Blyth K; Caldon CE; Herrmann D; Anderson KI; Timpson P; Nobis M
Cell Rep; 2021 Sep; 36(11):109689. PubMed ID: 34525350
[TBL] [Abstract][Full Text] [Related]
7. Approaches of targeting Rho GTPases in cancer drug discovery.
Lin Y; Zheng Y
Expert Opin Drug Discov; 2015; 10(9):991-1010. PubMed ID: 26087073
[TBL] [Abstract][Full Text] [Related]
8. Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models.
Torres-Sanchez A; Rivera-Robles M; Castillo-Pichardo L; Martínez-Ferrer M; Dorta-Estremera SM; Dharmawardhane S
Front Oncol; 2023; 13():1152458. PubMed ID: 37397366
[TBL] [Abstract][Full Text] [Related]
9. Brain endothelial cells promote breast cancer cell extravasation to the brain via EGFR-DOCK4-RAC1 signalling.
Galloni C; Egnuni T; Zahed Mohajerani S; Ye J; Mittnacht S; Speirs V; Lorger M; Mavria G
Commun Biol; 2024 May; 7(1):602. PubMed ID: 38762624
[TBL] [Abstract][Full Text] [Related]
10. Rac1 GTPase in pancreatic cancer.
Yan Y; Ouellette MM
Aging (Albany NY); 2015 Sep; 7(9):609-10. PubMed ID: 26420819
[No Abstract] [Full Text] [Related]
11. ∆Np63α inhibits Rac1 activation and cancer cell invasion through suppression of PREX1.
Aljagthmi AA; Hira A; Zhang J; Cooke M; Kazanietz MG; Kadakia MP
Cell Death Discov; 2024 Jan; 10(1):13. PubMed ID: 38191532
[TBL] [Abstract][Full Text] [Related]
12. Ovarian cancer G protein coupled receptor 1 suppresses cell migration of MCF7 breast cancer cells via a Gα12/13-Rho-Rac1 pathway.
Li J; Guo B; Wang J; Cheng X; Xu Y; Sang J
J Mol Signal; 2013 May; 8(1):6. PubMed ID: 23663350
[TBL] [Abstract][Full Text] [Related]
13. Sterically stabilized liposomes targeting P21 (RAC1) activated kinase-1 and secreted phospholipase A
Verma A; Najahi-Missaoui W; Cummings BS; Somanath PR
Oncol Lett; 2020 Nov; 20(5):179. PubMed ID: 32934746
[TBL] [Abstract][Full Text] [Related]
14. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
Zins K; Gunawardhana S; Lucas T; Abraham D; Aharinejad S
J Transl Med; 2013 Nov; 11():295. PubMed ID: 24279335
[TBL] [Abstract][Full Text] [Related]
15. Critical off-target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets.
Dütting S; Heidenreich J; Cherpokova D; Amin E; Zhang SC; Ahmadian MR; Brakebusch C; Nieswandt B
J Thromb Haemost; 2015 May; 13(5):827-38. PubMed ID: 25628054
[TBL] [Abstract][Full Text] [Related]
16. RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer.
Kaneto N; Yokoyama S; Hayakawa Y; Kato S; Sakurai H; Saiki I
Cancer Sci; 2014 Jul; 105(7):788-94. PubMed ID: 24750242
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of the small GTPase Cdc42 in regulation of epileptic-seizure in rats.
Zhang Y; Liu J; Luan G; Wang X
Neuroscience; 2015 Mar; 289():381-91. PubMed ID: 25595978
[TBL] [Abstract][Full Text] [Related]
18. Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.
Kumar A; Al-Sammarraie N; DiPette DJ; Singh US
Oncotarget; 2014 Nov; 5(22):11709-22. PubMed ID: 25365944
[TBL] [Abstract][Full Text] [Related]
19. The Rac1 inhibitor NSC23766 suppresses CREB signaling by targeting NMDA receptor function.
Hou H; Chávez AE; Wang CC; Yang H; Gu H; Siddoway BA; Hall BJ; Castillo PE; Xia H
J Neurosci; 2014 Oct; 34(42):14006-12. PubMed ID: 25319697
[TBL] [Abstract][Full Text] [Related]
20. Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure.
Pattabiraman PP; Epstein DL; Rao PV
J Ocul Biol; 2013 Jun; 1(1):. PubMed ID: 24932460
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]