BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 24041654)

  • 1. Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assay.
    Storaska AJ; Mei JP; Wu M; Li M; Wade SM; Blazer LL; Sjögren B; Hopkins CR; Lindsley CW; Lin Z; Babcock JJ; McManus OB; Neubig RR
    Cell Signal; 2013 Dec; 25(12):2848-55. PubMed ID: 24041654
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lack of receptor-selective effects of either RGS2, RGS3 or RGS4 on muscarinic M3- and gonadotropin-releasing hormone receptor-mediated signalling through G alpha q/11.
    Karakoula A; Tovey SC; Brighton PJ; Willars GB
    Eur J Pharmacol; 2008 Jun; 587(1-3):16-24. PubMed ID: 18457830
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins.
    Blazer LL; Roman DL; Chung A; Larsen MJ; Greedy BM; Husbands SM; Neubig RR
    Mol Pharmacol; 2010 Sep; 78(3):524-33. PubMed ID: 20571077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Single-cell imaging of intracellular Ca2+ and phospholipase C activity reveals that RGS 2, 3, and 4 differentially regulate signaling via the Galphaq/11-linked muscarinic M3 receptor.
    Tovey SC; Willars GB
    Mol Pharmacol; 2004 Dec; 66(6):1453-64. PubMed ID: 15383626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors.
    Blazer LL; Storaska AJ; Jutkiewicz EM; Turner EM; Calcagno M; Wade SM; Wang Q; Huang XP; Traynor JR; Husbands SM; Morari M; Neubig RR
    ACS Chem Neurosci; 2015 Jun; 6(6):911-9. PubMed ID: 25844489
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of peptides that inhibit regulator of G protein signaling 4 function.
    Wang Y; Lee Y; Zhang J; Young KH
    Pharmacology; 2008; 82(2):97-104. PubMed ID: 18547979
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay.
    Roman DL; Talbot JN; Roof RA; Sunahara RK; Traynor JR; Neubig RR
    Mol Pharmacol; 2007 Jan; 71(1):169-75. PubMed ID: 17012620
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interplay of cysteine exposure and global protein dynamics in small-molecule recognition by a regulator of G-protein signaling protein.
    Mohammadi M; Mohammadiarani H; Shaw VS; Neubig RR; Vashisth H
    Proteins; 2019 Feb; 87(2):146-156. PubMed ID: 30521141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential Protein Dynamics of Regulators of G-Protein Signaling: Role in Specificity of Small-Molecule Inhibitors.
    Shaw VS; Mohammadiarani H; Vashisth H; Neubig RR
    J Am Chem Soc; 2018 Mar; 140(9):3454-3460. PubMed ID: 29460621
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face.
    Kimple AJ; Willard FS; Giguère PM; Johnston CA; Mocanu V; Siderovski DP
    Biochim Biophys Acta; 2007 Sep; 1774(9):1213-20. PubMed ID: 17660054
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells.
    Ghil S; McCoy KL; Hepler JR
    PLoS One; 2014; 9(4):e95355. PubMed ID: 24743392
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric inhibition of the regulator of G protein signaling-Galpha protein-protein interaction by CCG-4986.
    Roman DL; Blazer LL; Monroy CA; Neubig RR
    Mol Pharmacol; 2010 Sep; 78(3):360-5. PubMed ID: 20530129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RGS3 and RGS4 differentially associate with G protein-coupled receptor-Kir3 channel signaling complexes revealing two modes of RGS modulation. Precoupling and collision coupling.
    Jaén C; Doupnik CA
    J Biol Chem; 2006 Nov; 281(45):34549-60. PubMed ID: 16973624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization and comparison of RGS2 and RGS4 as GTPase-activating proteins for m2 muscarinic receptor-stimulated G(i).
    Cladman W; Chidiac P
    Mol Pharmacol; 2002 Sep; 62(3):654-9. PubMed ID: 12181442
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulators of G-protein signaling, RGS2 and RGS4, inhibit protease-activated receptor 4-mediated signaling by forming a complex with the receptor and Gα in live cells.
    Kim Y; Ghil S
    Cell Commun Signal; 2020 Jun; 18(1):86. PubMed ID: 32517689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential contribution of GTPase activation and effector antagonism to the inhibitory effect of RGS proteins on Gq-mediated signaling in vivo.
    Anger T; Zhang W; Mende U
    J Biol Chem; 2004 Feb; 279(6):3906-15. PubMed ID: 14630933
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Allosteric regulation of GAP activity by phospholipids in regulators of G-protein signaling.
    Tu Y; Wilkie TM
    Methods Enzymol; 2004; 389():89-105. PubMed ID: 15313561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins.
    Blazer LL; Zhang H; Casey EM; Husbands SM; Neubig RR
    Biochemistry; 2011 Apr; 50(15):3181-92. PubMed ID: 21329361
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conformational dynamics of a regulator of G-protein signaling protein reveals a mechanism of allosteric inhibition by a small molecule.
    Vashisth H; Storaska AJ; Neubig RR; Brooks CL
    ACS Chem Biol; 2013 Dec; 8(12):2778-84. PubMed ID: 24093330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulators of G-protein signaling (RGS) 4, insertion into model membranes and inhibition of activity by phosphatidic acid.
    Ouyang YS; Tu Y; Barker SA; Yang F
    J Biol Chem; 2003 Mar; 278(13):11115-22. PubMed ID: 12538649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.