These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. 244-MPT overcomes gefitinib resistance in non-small cell lung cancer cells. Zhang Y; Yao K; Shi C; Jiang Y; Liu K; Zhao S; Chen H; Reddy K; Zhang C; Chang X; Ryu J; Bode AM; Dong Z; Dong Z Oncotarget; 2015 Dec; 6(42):44274-88. PubMed ID: 26517520 [TBL] [Abstract][Full Text] [Related]
3. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. Nakagawa T; Takeuchi S; Yamada T; Nanjo S; Ishikawa D; Sano T; Kita K; Nakamura T; Matsumoto K; Suda K; Mitsudomi T; Sekido Y; Uenaka T; Yano S Mol Cancer Ther; 2012 Oct; 11(10):2149-57. PubMed ID: 22844075 [TBL] [Abstract][Full Text] [Related]
4. Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab. Chen G; Kronenberger P; Teugels E; Umelo IA; De Grève J BMC Med; 2012 Mar; 10():28. PubMed ID: 22436374 [TBL] [Abstract][Full Text] [Related]
5. Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations. Lazzara MJ; Lane K; Chan R; Jasper PJ; Yaffe MB; Sorger PK; Jacks T; Neel BG; Lauffenburger DA Cancer Res; 2010 May; 70(9):3843-50. PubMed ID: 20406974 [TBL] [Abstract][Full Text] [Related]
6. Curcumin induces EGFR degradation in lung adenocarcinoma and modulates p38 activation in intestine: the versatile adjuvant for gefitinib therapy. Lee JY; Lee YM; Chang GC; Yu SL; Hsieh WY; Chen JJ; Chen HW; Yang PC PLoS One; 2011; 6(8):e23756. PubMed ID: 21858220 [TBL] [Abstract][Full Text] [Related]
7. Antitumor activity of HM781-36B, a highly effective pan-HER inhibitor in erlotinib-resistant NSCLC and other EGFR-dependent cancer models. Cha MY; Lee KO; Kim M; Song JY; Lee KH; Park J; Chae YJ; Kim YH; Suh KH; Lee GS; Park SB; Kim MS Int J Cancer; 2012 May; 130(10):2445-54. PubMed ID: 21732342 [TBL] [Abstract][Full Text] [Related]
8. Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib. Sun Y; Meyers BA; Czako B; Leonard P; Mseeh F; Harris AL; Wu Q; Johnson S; Parker CA; Cross JB; Di Francesco ME; Bivona BJ; Bristow CA; Burke JP; Carrillo CC; Carroll CL; Chang Q; Feng N; Gao G; Gera S; Giuliani V; Huang JK; Jiang Y; Kang Z; Kovacs JJ; Liu CY; Lopez AM; Ma X; Mandal PK; McAfoos T; Miller MA; Mullinax RA; Peoples M; Ramamoorthy V; Seth S; Spencer ND; Suzuki E; Williams CC; Yu SS; Zuniga AM; Draetta GF; Marszalek JR; Heffernan TP; Kohl NE; Jones P Cancer Res; 2020 Nov; 80(21):4840-4853. PubMed ID: 32928921 [TBL] [Abstract][Full Text] [Related]
9. Diminished functional role and altered localization of SHP2 in non-small cell lung cancer cells with EGFR-activating mutations. Furcht CM; Muñoz Rojas AR; Nihalani D; Lazzara MJ Oncogene; 2013 May; 32(18):2346-55, 2355.e1-10. PubMed ID: 22777356 [TBL] [Abstract][Full Text] [Related]
10. Antitumor activity of selective MEK1/2 inhibitor AZD6244 in combination with PI3K/mTOR inhibitor BEZ235 in gefitinib-resistant NSCLC xenograft models. Qu Y; Wu X; Yin Y; Yang Y; Ma D; Li H J Exp Clin Cancer Res; 2014 Jun; 33(1):52. PubMed ID: 24939055 [TBL] [Abstract][Full Text] [Related]
11. A novel EGFR inhibitor suppresses survivin expression and tumor growth in human gefitinib-resistant EGFR-wild type and -T790M non-small cell lung cancer. Wang SP; Hsu YP; Chang CJ; Chan YC; Chen CH; Wang RH; Liu KK; Pan PY; Wu YH; Yang CM; Chen C; Yang JM; Liang MC; Wong KK; Chao JI Biochem Pharmacol; 2021 Nov; 193():114792. PubMed ID: 34597670 [TBL] [Abstract][Full Text] [Related]
12. Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer. Tang Z; Du R; Jiang S; Wu C; Barkauskas DS; Richey J; Molter J; Lam M; Flask C; Gerson S; Dowlati A; Liu L; Lee Z; Halmos B; Wang Y; Kern JA; Ma PC Br J Cancer; 2008 Sep; 99(6):911-22. PubMed ID: 19238632 [TBL] [Abstract][Full Text] [Related]
13. Combined Erlotinib and Cetuximab overcome the acquired resistance to epidermal growth factor receptors tyrosine kinase inhibitor in non-small-cell lung cancer. Wang M; Zhao J; Zhang LM; Li H; Yu JP; Ren XB; Wang CL J Cancer Res Clin Oncol; 2012 Dec; 138(12):2069-77. PubMed ID: 22821179 [TBL] [Abstract][Full Text] [Related]
14. Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer. Ono N; Yamazaki T; Tsukaguchi T; Fujii T; Sakata K; Suda A; Tsukuda T; Mio T; Ishii N; Kondoh O; Aoki Y Cancer Sci; 2013 Oct; 104(10):1346-52. PubMed ID: 23863134 [TBL] [Abstract][Full Text] [Related]
15. Enhanced anticancer effect of the combination of BIBW2992 and thymidylate synthase-targeted agents in non-small cell lung cancer with the T790M mutation of epidermal growth factor receptor. Takezawa K; Okamoto I; Tanizaki J; Kuwata K; Yamaguchi H; Fukuoka M; Nishio K; Nakagawa K Mol Cancer Ther; 2010 Jun; 9(6):1647-56. PubMed ID: 20530710 [TBL] [Abstract][Full Text] [Related]
16. The T790M "gatekeeper" mutation in EGFR mediates resistance to low concentrations of an irreversible EGFR inhibitor. Godin-Heymann N; Ulkus L; Brannigan BW; McDermott U; Lamb J; Maheswaran S; Settleman J; Haber DA Mol Cancer Ther; 2008 Apr; 7(4):874-9. PubMed ID: 18413800 [TBL] [Abstract][Full Text] [Related]
17. Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinib. Chen G; Noor A; Kronenberger P; Teugels E; Umelo IA; De Grève J PLoS One; 2013; 8(3):e59708. PubMed ID: 23527257 [TBL] [Abstract][Full Text] [Related]
18. Gefitinib analogue V1801 induces apoptosis of T790M EGFR-harboring lung cancer cells by up-regulation of the BH-3 only protein Noxa. Zhang B; Jiao J; Liu Y; Guo LX; Zhou B; Li GQ; Yao ZJ; Zhou GB PLoS One; 2012; 7(11):e48748. PubMed ID: 23185274 [TBL] [Abstract][Full Text] [Related]
19. Effects of Src inhibitors on cell growth and epidermal growth factor receptor and MET signaling in gefitinib-resistant non-small cell lung cancer cells with acquired MET amplification. Yoshida T; Okamoto I; Okamoto W; Hatashita E; Yamada Y; Kuwata K; Nishio K; Fukuoka M; Jänne PA; Nakagawa K Cancer Sci; 2010 Jan; 101(1):167-72. PubMed ID: 19804422 [TBL] [Abstract][Full Text] [Related]
20. RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer. Kaneto N; Yokoyama S; Hayakawa Y; Kato S; Sakurai H; Saiki I Cancer Sci; 2014 Jul; 105(7):788-94. PubMed ID: 24750242 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]