153 related articles for article (PubMed ID: 24047231)
1. Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands.
Yenugonda VM; Xiao Y; Levin ED; Rezvani AH; Tran T; Al-Muhtasib N; Sahibzada N; Xie T; Wells C; Slade S; Johnson JE; Dakshanamurthy S; Kong HS; Tomita Y; Liu Y; Paige M; Kellar KJ; Brown ML
J Med Chem; 2013 Nov; 56(21):8404-21. PubMed ID: 24047231
[TBL] [Abstract][Full Text] [Related]
2. Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them.
Xiao Y; Fan H; Musachio JL; Wei ZL; Chellappan SK; Kozikowski AP; Kellar KJ
Mol Pharmacol; 2006 Oct; 70(4):1454-60. PubMed ID: 16857741
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and pharmacological characterization of new neuronal nicotinic acetylcholine receptor ligands derived from Sazetidine-A.
Liu Y; Paige M; Olson TT; Al-Muhtasib N; Xie T; Hou S; White MP; Cordova A; Guo JL; Kellar KJ; Xiao Y; Brown ML
Bioorg Med Chem Lett; 2014 Jul; 24(13):2954-6. PubMed ID: 24844195
[TBL] [Abstract][Full Text] [Related]
4. 5-substituted derivatives of 6-halogeno-3-((2-(S)-azetidinyl)methoxy)pyridine and 6-halogeno-3-((2-(S)-pyrrolidinyl)methoxy)pyridine with low picomolar affinity for alpha4beta2 nicotinic acetylcholine receptor and wide range of lipophilicity: potential probes for imaging with positron emission tomography.
Zhang Y; Pavlova OA; Chefer SI; Hall AW; Kurian V; Brown LL; Kimes AS; Mukhin AG; Horti AG
J Med Chem; 2004 May; 47(10):2453-65. PubMed ID: 15115389
[TBL] [Abstract][Full Text] [Related]
5. Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors.
Zwart R; Carbone AL; Moroni M; Bermudez I; Mogg AJ; Folly EA; Broad LM; Williams AC; Zhang D; Ding C; Heinz BA; Sher E
Mol Pharmacol; 2008 Jun; 73(6):1838-43. PubMed ID: 18367540
[TBL] [Abstract][Full Text] [Related]
6. Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists.
Liu J; Eaton JB; Caldarone B; Lukas RJ; Kozikowski AP
J Med Chem; 2010 Oct; 53(19):6973-85. PubMed ID: 20822184
[TBL] [Abstract][Full Text] [Related]
7. Preparation and characterization of N-(3-pyridinyl) spirocyclic diamines as ligands for nicotinic acetylcholine receptors.
Sippy KB; Anderson DJ; Bunnelle WH; Hutchins CW; Schrimpf MR
Bioorg Med Chem Lett; 2009 Mar; 19(6):1682-5. PubMed ID: 19232492
[TBL] [Abstract][Full Text] [Related]
8. 2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling.
Koren AO; Horti AG; Mukhin AG; Gündisch D; Kimes AS; Dannals RF; London ED
J Med Chem; 1998 Sep; 41(19):3690-8. PubMed ID: 9733494
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues.
Ondachi PW; Castro AH; Luetje CW; Wageman CR; Marks MJ; Damaj MI; Mascarella SW; Navarro HA; Carroll FI
ACS Chem Neurosci; 2016 Jul; 7(7):1004-12. PubMed ID: 27166021
[TBL] [Abstract][Full Text] [Related]
10. Neonicotinic analogues: selective antagonists for α4β2 nicotinic acetylcholine receptors.
Faundez-Parraguez M; Farias-Rabelo N; Gonzalez-Gutierrez JP; Etcheverry-Berrios A; Alzate-Morales J; Adasme-Carreño F; Varas R; Bermudez I; Iturriaga-Vasquez P
Bioorg Med Chem; 2013 May; 21(10):2687-94. PubMed ID: 23561269
[TBL] [Abstract][Full Text] [Related]
11. Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain.
Hussmann GP; Turner JR; Lomazzo E; Venkatesh R; Cousins V; Xiao Y; Yasuda RP; Wolfe BB; Perry DC; Rezvani AH; Levin ED; Blendy JA; Kellar KJ
J Pharmacol Exp Ther; 2012 Nov; 343(2):441-50. PubMed ID: 22899752
[TBL] [Abstract][Full Text] [Related]
12. Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats.
Levin ED; Rezvani AH; Xiao Y; Slade S; Cauley M; Wells C; Hampton D; Petro A; Rose JE; Brown ML; Paige MA; McDowell BE; Kellar KJ
J Pharmacol Exp Ther; 2010 Mar; 332(3):933-9. PubMed ID: 20007754
[TBL] [Abstract][Full Text] [Related]
13. Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression.
Kozikowski AP; Eaton JB; Bajjuri KM; Chellappan SK; Chen Y; Karadi S; He R; Caldarone B; Manzano M; Yuen PW; Lukas RJ
ChemMedChem; 2009 Aug; 4(8):1279-91. PubMed ID: 19569163
[TBL] [Abstract][Full Text] [Related]
14. Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist.
Hansen CP; Jensen AA; Christensen JK; Balle T; Liljefors T; Frølund B
J Med Chem; 2008 Dec; 51(23):7380-95. PubMed ID: 18989912
[TBL] [Abstract][Full Text] [Related]
15. Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors.
Abreo MA; Lin NH; Garvey DS; Gunn DE; Hettinger AM; Wasicak JT; Pavlik PA; Martin YC; Donnelly-roberts DL; Anderson DJ; Sullivan JP; Williams M; Arneric SP; Holladay MW
J Med Chem; 1996 Feb; 39(4):817-25. PubMed ID: 8632405
[TBL] [Abstract][Full Text] [Related]
16. Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype.
Matera C; Quadri M; Sciaccaluga M; Pomè DY; Fasoli F; De Amici M; Fucile S; Gotti C; Dallanoce C; Grazioso G
Eur J Med Chem; 2016 Jan; 108():392-405. PubMed ID: 26706350
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological activity of 5'-phenyl-1,2,5,6-tetrahydro-3,3'-bipyridine analogues as potential antagonists of nicotinic acetylcholine receptors.
Jin Y; Huang X; Papke RL; Jutkiewicz EM; Showalter HD; Zhan CG
Bioorg Med Chem Lett; 2017 Sep; 27(18):4350-4353. PubMed ID: 28838693
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors.
Mu L; Drandarov K; Bisson WH; Schibig A; Wirz C; Schubiger PA; Westera G
Eur J Med Chem; 2006 May; 41(5):640-50. PubMed ID: 16545497
[TBL] [Abstract][Full Text] [Related]
19. Novel and potent 6-chloro-3-pyridinyl ligands for the alpha4beta2 neuronal nicotinic acetylcholine receptor.
Latli B; D'Amour K; Casida JE
J Med Chem; 1999 Jun; 42(12):2227-34. PubMed ID: 10377228
[TBL] [Abstract][Full Text] [Related]
20. α4β2 neuronal nicotinic receptor positive allosteric modulation: an approach for improving the therapeutic index of α4β2 nAChR agonists in pain.
Lee CH; Zhu C; Malysz J; Campbell T; Shaughnessy T; Honore P; Polakowski J; Gopalakrishnan M
Biochem Pharmacol; 2011 Oct; 82(8):959-66. PubMed ID: 21763685
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]