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3. Probing the structure of hirudin from Hirudinaria manillensis by limited proteolysis. Isolation, characterization and thrombin-inhibitory properties of N-terminal fragments. Vindigni A; De Filippis V; Zanotti G; Visco C; Orsini G; Fontana A Eur J Biochem; 1994 Dec; 226(2):323-33. PubMed ID: 8001550 [TBL] [Abstract][Full Text] [Related]
4. Use of fragments of hirudin to investigate thrombin-hirudin interaction. Dennis S; Wallace A; Hofsteenge J; Stone SR Eur J Biochem; 1990 Feb; 188(1):61-6. PubMed ID: 2180697 [TBL] [Abstract][Full Text] [Related]
5. Thermodynamic investigation of hirudin binding to the slow and fast forms of thrombin: evidence for folding transitions in the inhibitor and protease coupled to binding. Ayala YM; Vindigni A; Nayal M; Spolar RS; Record MT; Di Cera E J Mol Biol; 1995 Nov; 253(5):787-98. PubMed ID: 7473752 [TBL] [Abstract][Full Text] [Related]
6. The structural elements of hirudin which bind to the fibrinogen recognition site of thrombin are exclusively located within its acidic C-terminal tail. Chang JY; Ngai PK; Rink H; Dennis S; Schlaeppi JM FEBS Lett; 1990 Feb; 261(2):287-90. PubMed ID: 2107100 [TBL] [Abstract][Full Text] [Related]
7. Structure-function relationships of the C-terminal functional domain of hirudin and its variants. Krstenansky JL; Mao SJ Blood Coagul Fibrinolysis; 1991 Feb; 2(1):91-6. PubMed ID: 1773003 [TBL] [Abstract][Full Text] [Related]
9. Preparation of monoclonal antibodies to hirudin and hirudin peptides. A method for studying the hirudin--thrombin interaction. Schlaeppi JM; Vekemans S; Rink H; Chang JY Eur J Biochem; 1990 Mar; 188(2):463-70. PubMed ID: 1690651 [TBL] [Abstract][Full Text] [Related]
10. Structure-function and refolding studies of the thrombin-specific inhibitor hirudin. Johnson PH; Sze P; Winant RC; Hudson D; Underhill P; Lazar JB; Olsen C; Almquist R Haemostasis; 1991; 21 Suppl 1():41-8. PubMed ID: 1894196 [TBL] [Abstract][Full Text] [Related]
11. Thrombin inhibition by hirudin: how hirudin inhibits thrombin. Fenton JW; Villanueva GB; Ofosu FA; Maraganore JM Haemostasis; 1991; 21 Suppl 1():27-31. PubMed ID: 1894193 [TBL] [Abstract][Full Text] [Related]
12. Recombinant hirudin: kinetic mechanism for the inhibition of human thrombin. Stone SR; Hofsteenge J Protein Eng; 1991 Feb; 4(3):295-300. PubMed ID: 1857714 [TBL] [Abstract][Full Text] [Related]
13. Mechanism of the inhibition of alpha-thrombin by hirudin-derived fragments hirudin(1-47) and hirudin(45-65). Schmitz T; Rothe M; Dodt J Eur J Biochem; 1991 Jan; 195(1):251-6. PubMed ID: 1991472 [TBL] [Abstract][Full Text] [Related]
14. Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech. Mao SJ; Yates MT; Blankenship DT; Cardin AD; Krstenansky JL; Lovenberg W; Jackson RL Anal Biochem; 1987 Mar; 161(2):514-8. PubMed ID: 3578808 [TBL] [Abstract][Full Text] [Related]
15. A new class of potent thrombin inhibitors that incorporates a scissile pseudopeptide bond. DiMaio J; Ni F; Gibbs B; Konishi Y FEBS Lett; 1991 Apr; 282(1):47-52. PubMed ID: 2026264 [TBL] [Abstract][Full Text] [Related]
16. Inhibition of in vitro clot growth by r-hirudin is more effective and longer sustained than by an analogous peptide. Römisch J; Stöhr HA; Stauss H; Koschinsky R; Stüber W; Pâques EP Thromb Haemost; 1994 Mar; 71(3):320-4. PubMed ID: 8029796 [TBL] [Abstract][Full Text] [Related]
17. Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I. Myles T; Le Bonniec BF; Betz A; Stone SR Biochemistry; 2001 Apr; 40(16):4972-9. PubMed ID: 11305913 [TBL] [Abstract][Full Text] [Related]
18. Effect of the hirudin carboxy-terminal peptide 54-65 on the interaction of thrombin with platelets. Jandrot-Perrus M; Huisse MG; Krstenansky JL; Bezeaud A; Guillin MC Thromb Haemost; 1991 Sep; 66(3):300-5. PubMed ID: 1746000 [TBL] [Abstract][Full Text] [Related]
20. Deciphering the structural elements of hirudin C-terminal peptide that bind to the fibrinogen recognition site of alpha-thrombin. Chang JY Biochemistry; 1991 Jul; 30(27):6656-61. PubMed ID: 2065053 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]