These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 24050245)

  • 1. Exposition and reactivity optimization to predict sites of metabolism in chemicals.
    Cruciani G; Baroni M; Benedetti P; Goracci L; Fortuna CG
    Drug Discov Today Technol; 2013; 10(1):e155-65. PubMed ID: 24050245
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Designing better drugs: predicting cytochrome P450 metabolism.
    de Groot MJ
    Drug Discov Today; 2006 Jul; 11(13-14):601-6. PubMed ID: 16793528
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico site of metabolism prediction of cytochrome P450-mediated biotransformations.
    Tarcsay Á; Keseru GM
    Expert Opin Drug Metab Toxicol; 2011 Mar; 7(3):299-312. PubMed ID: 21291341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SOMEViz: a web service for site of metabolism estimating and visualizing.
    Shen Q; Zheng M; Lu J; Luo C; Zhu W; Chen K; Luo X; Jiang H
    Protein Pept Lett; 2012 Sep; 19(9):905-9. PubMed ID: 22894162
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pragmatic approaches to using computational methods to predict xenobiotic metabolism.
    Piechota P; Cronin MT; Hewitt M; Madden JC
    J Chem Inf Model; 2013 Jun; 53(6):1282-93. PubMed ID: 23718189
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist.
    Cruciani G; Carosati E; De Boeck B; Ethirajulu K; Mackie C; Howe T; Vianello R
    J Med Chem; 2005 Nov; 48(22):6970-9. PubMed ID: 16250655
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-based drug metabolism predictions for drug design.
    Sun H; Scott DO
    Chem Biol Drug Des; 2010 Jan; 75(1):3-17. PubMed ID: 19878193
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SOMP: web server for in silico prediction of sites of metabolism for drug-like compounds.
    Rudik A; Dmitriev A; Lagunin A; Filimonov D; Poroikov V
    Bioinformatics; 2015 Jun; 31(12):2046-8. PubMed ID: 25777527
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of drug metabolism and interactions on the basis of in vitro investigations.
    Pelkonen O; Turpeinen M; Uusitalo J; Rautio A; Raunio H
    Basic Clin Pharmacol Toxicol; 2005 Mar; 96(3):167-75. PubMed ID: 15733211
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computational modeling of P450s for toxicity prediction.
    Mishra NK
    Expert Opin Drug Metab Toxicol; 2011 Oct; 7(10):1211-31. PubMed ID: 21864218
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism site prediction based on xenobiotic structural formulas and PASS prediction algorithm.
    Rudik AV; Dmitriev AV; Lagunin AA; Filimonov DA; Poroikov VV
    J Chem Inf Model; 2014 Feb; 54(2):498-507. PubMed ID: 24417355
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 2D SMARTCyp reactivity-based site of metabolism prediction for major drug-metabolizing cytochrome P450 enzymes.
    Liu R; Liu J; Tawa G; Wallqvist A
    J Chem Inf Model; 2012 Jun; 52(6):1698-712. PubMed ID: 22631565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use of physiologically based pharmacokinetic modeling for assessment of drug-drug interactions.
    Baneyx G; Fukushima Y; Parrott N
    Future Med Chem; 2012 Apr; 4(5):681-93. PubMed ID: 22458685
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling of human cytochrome p450-mediated drug metabolism using unsupervised machine learning approach.
    Korolev D; Balakin KV; Nikolsky Y; Kirillov E; Ivanenkov YA; Savchuk NP; Ivashchenko AA; Nikolskaya T
    J Med Chem; 2003 Aug; 46(17):3631-43. PubMed ID: 12904067
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico prediction of harmful effects triggered by drugs and chemicals.
    Vedani A; Dobler M; Lill MA
    Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):398-407. PubMed ID: 16045954
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Site of metabolism prediction for six biotransformations mediated by cytochromes P450.
    Zheng M; Luo X; Shen Q; Wang Y; Du Y; Zhu W; Jiang H
    Bioinformatics; 2009 May; 25(10):1251-8. PubMed ID: 19286831
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
    Gómez-Lechón MJ; Castell JV; Donato MT
    Chem Biol Interact; 2007 May; 168(1):30-50. PubMed ID: 17134688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolites: structure determination and prediction.
    Cruciani G
    Drug Discov Today Technol; 2013; 10(1):e145-6. PubMed ID: 24050243
    [No Abstract]   [Full Text] [Related]  

  • 19. In silico pKa prediction and ADME profiling.
    Cruciani G; Milletti F; Storchi L; Sforna G; Goracci L
    Chem Biodivers; 2009 Nov; 6(11):1812-21. PubMed ID: 19937818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Approach to the prediction of the contribution of major cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage.
    Emoto C; Murase S; Iwasaki K
    Xenobiotica; 2006 Aug; 36(8):671-83. PubMed ID: 16891248
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.