BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 24050886)

  • 1. Nitroreductase-activated nitric oxide (NO) prodrugs.
    Sharma K; Sengupta K; Chakrapani H
    Bioorg Med Chem Lett; 2013 Nov; 23(21):5964-7. PubMed ID: 24050886
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Permeability changes in response to NONOate and NONOate prodrug derived nitric oxide in a blood-brain barrier model formed by primary porcine endothelial cells.
    Winter S; Konter J; Scheler S; Lehmann J; Fahr A
    Nitric Oxide; 2008 May; 18(3):229-39. PubMed ID: 18284923
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Das D; Yu G; Velázquez C; Suresh MR; Knaus EE
    Bioorg Med Chem; 2009 Jul; 17(14):5182-8. PubMed ID: 19500994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductase.
    Hay MP; Atwell GJ; Wilson WR; Pullen SM; Denny WA
    J Med Chem; 2003 Jun; 46(12):2456-66. PubMed ID: 12773049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez CA; Chen QH; Citro ML; Keefer LK; Knaus EE
    J Med Chem; 2008 Mar; 51(6):1954-61. PubMed ID: 18314945
    [TBL] [Abstract][Full Text] [Related]  

  • 6. E. coli nitroreductase/CB1954 gene-directed enzyme prodrug therapy: role of arylamine N-acetlytransferase 2.
    Mitchell DJ; Minchin RF
    Cancer Gene Ther; 2008 Nov; 15(11):758-64. PubMed ID: 18600257
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents.
    Maciag AE; Saavedra JE; Chakrapani H
    Anticancer Agents Med Chem; 2009 Sep; 9(7):798-803. PubMed ID: 19538173
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cellular distribution studies of the nitric oxide-generating antineoplastic prodrug O(2) -(2,4-dinitrophenyl)1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate formulated in Pluronic P123 micelles.
    Kaur I; Terrazas M; Kosak KM; Kern SE; Boucher KM; Shami PJ
    J Pharm Pharmacol; 2013 Sep; 65(9):1329-36. PubMed ID: 23927471
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP; Anderson RF; Ferry DM; Wilson WR; Denny WA
    J Med Chem; 2003 Dec; 46(25):5533-45. PubMed ID: 14640560
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted diazeniumdiolates: localized nitric oxide release from glioma-specific peptides and proteins.
    Safdar S; Taite LJ
    Int J Pharm; 2012 Jan; 422(1-2):264-70. PubMed ID: 22101282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Velázquez C; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem; 2008 Nov; 16(22):9694-8. PubMed ID: 18930406
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.
    Chakrapani H; Kalathur RC; Maciag AE; Citro ML; Ji X; Keefer LK; Saavedra JE
    Bioorg Med Chem; 2008 Nov; 16(22):9764-71. PubMed ID: 18930407
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez C; Praveen Rao PN; Knaus EE
    J Med Chem; 2005 Jun; 48(12):4061-7. PubMed ID: 15943479
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of novel nitroreductase enzyme-activated nitric oxide prodrugs to site-specifically kill bacteria.
    Hibbard HAJ; Reynolds MM
    Bioorg Chem; 2019 Dec; 93():103318. PubMed ID: 31586703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nitroreductase-based GDEPT.
    Denny WA
    Curr Pharm Des; 2002; 8(15):1349-61. PubMed ID: 12052212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation.
    Jiang Y; Han J; Yu C; Vass SO; Searle PF; Browne P; Knox RJ; Hu L
    J Med Chem; 2006 Jul; 49(14):4333-43. PubMed ID: 16821793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Investigation of alternative prodrugs for use with E. coli nitroreductase in 'suicide gene' approaches to cancer therapy.
    Bailey SM; Knox RJ; Hobbs SM; Jenkins TC; Mauger AB; Melton RG; Burke PJ; Connors TA; Hart IR
    Gene Ther; 1996 Dec; 3(12):1143-50. PubMed ID: 8986441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of cephalosporin-3'-diazeniumdiolates: biofilm dispersing NO-donor prodrugs activated by β-lactamase.
    Yepuri NR; Barraud N; Mohammadi NS; Kardak BG; Kjelleberg S; Rice SA; Kelso MJ
    Chem Commun (Camb); 2013 May; 49(42):4791-3. PubMed ID: 23603842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diazen-1-ium-1,2-diolated and nitrooxyethyl nitric oxide donor ester prodrugs of anti-inflammatory (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic acids: synthesis, cyclooxygenase inhibition, and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Chen QH; Knaus EE
    Bioorg Med Chem; 2008 Mar; 16(6):3302-8. PubMed ID: 18096394
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitrobenzyl carbamate prodrugs of enediynes for nitroreductase gene-directed enzyme prodrug therapy (GDEPT).
    Hay MP; Wilson WR; Denny WA
    Bioorg Med Chem Lett; 1999 Dec; 9(24):3417-22. PubMed ID: 10617083
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.