BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 24055044)

  • 1. Triphenylphosphonium salts of 1,2,4-benzothiadiazine 1,1-dioxides related to diazoxide targeting mitochondrial ATP-sensitive potassium channels.
    Constant-Urban C; Charif M; Goffin E; Van Heugen JC; Elmoualij B; Chiap P; Mouithys-Mickalad A; Serteyn D; Lebrun P; Pirotte B; De Tullio P
    Bioorg Med Chem Lett; 2013 Nov; 23(21):5878-81. PubMed ID: 24055044
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chloro-substituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity.
    Pirotte B; de Tullio P; Nguyen QA; Somers F; Fraikin P; Florence X; Wahl P; Hansen JB; Lebrun P
    J Med Chem; 2010 Jan; 53(1):147-54. PubMed ID: 19919106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of modified 4H-1,2,4-benzothiadiazine-1,1-dioxides and determination of their affinity and selectivity for different types of K(ATP) channels.
    Lachenicht S; Fischer A; Schmidt C; Winkler M; Rood A; Lemoine H; Braun M
    ChemMedChem; 2009 Nov; 4(11):1850-8. PubMed ID: 19774590
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hydroxylated analogues of ATP-sensitive potassium channel openers belonging to the group of 6- and/or 7-substituted 3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides: toward an improvement in sulfonylurea receptor 1 selectivity and metabolism stability.
    de Tullio P; Servais AC; Fillet M; Gillotin F; Somers F; Chiap P; Lebrun P; Pirotte B
    J Med Chem; 2011 Dec; 54(24):8353-61. PubMed ID: 22077416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels.
    Pirotte B; de Tullio P; Boverie S; Michaux C; Lebrun P
    J Med Chem; 2011 May; 54(9):3188-99. PubMed ID: 21428460
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides.
    de Tullio P; Becker B; Boverie S; Dabrowski M; Wahl P; Antoine MH; Somers F; Sebille S; Ouedraogo R; Hansen JB; Lebrun P; Pirotte B
    J Med Chem; 2003 Jul; 46(15):3342-53. PubMed ID: 12852765
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect on insulin release of compounds structurally related to the potassium-channel opener 7-chloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide (BPDZ 73): introduction of heteroatoms on the 3-alkylamino side chain of the benzothiadiazine 1,1-dioxide ring.
    Boverie S; Antoine MH; de Tullio P; Somers F; Becker B; Sebille S; Lebrun P; Pirotte B
    J Pharm Pharmacol; 2001 Jul; 53(7):973-80. PubMed ID: 11480549
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1,4,2-Benzo/pyridodithiazine 1,1-dioxides structurally related to the ATP-sensitive potassium channel openers 1,2,4-Benzo/pyridothiadiazine 1,1-dioxides exert a myorelaxant activity linked to a distinct mechanism of action.
    Pirotte B; de Tullio P; Florence X; Goffin E; Somers F; Boverie S; Lebrun P
    J Med Chem; 2013 Apr; 56(8):3247-56. PubMed ID: 23517501
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4H-1,2,4-Pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2, 4-pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors: design, synthesis, pharmacology, and structure-activity relationships.
    Pirotte B; Podona T; Diouf O; de Tullio P; Lebrun P; Dupont L; Somers F; Delarge J; Morain P; Lestage P; Lepagnol J; Spedding M
    J Med Chem; 1998 Jul; 41(16):2946-59. PubMed ID: 9685234
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria.
    Brustovetsky T; Shalbuyeva N; Brustovetsky N
    J Physiol; 2005 Oct; 568(Pt 1):47-59. PubMed ID: 16051627
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancement of liver regeneration by adenosine triphosphate-sensitive K⁺ channel opener (diazoxide) after partial hepatectomy.
    Nakagawa Y; Yoshioka M; Abe Y; Uchinami H; Ohba T; Ono K; Yamamoto Y
    Transplantation; 2012 Jun; 93(11):1094-100. PubMed ID: 22466787
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener.
    Dabrowski M; Ashcroft FM; Ashfield R; Lebrun P; Pirotte B; Egebjerg J; Bondo Hansen J; Wahl P
    Diabetes; 2002 Jun; 51(6):1896-906. PubMed ID: 12031979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological and histochemical distinctions between molecularly defined sarcolemmal KATP channels and native cardiac mitochondrial KATP channels.
    Hu H; Sato T; Seharaseyon J; Liu Y; Johns DC; O'Rourke B; Marbán E
    Mol Pharmacol; 1999 Jun; 55(6):1000-5. PubMed ID: 10347240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel.
    Ng B; Kang Y; Xie H; Sun H; Gaisano HY
    Cardiovasc Res; 2008 Dec; 80(3):365-74. PubMed ID: 18703534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides.
    Boverie S; Antoine MH; Somers F; Becker B; Sebille S; Ouedraogo R; Counerotte S; Pirotte B; Lebrun P; de Tullio P
    J Med Chem; 2005 May; 48(10):3492-503. PubMed ID: 15887958
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coupling of liquid chromatography/tandem mass spectrometry and liquid chromatography/solid-phase extraction/NMR techniques for the structural identification of metabolites following in vitro biotransformation of SUR1-selective ATP-sensitive potassium channel openers.
    Gillotin F; Chiap P; Frédérich M; Van Heugen JC; Francotte P; Lebrun P; Pirotte B; de Tullio P
    Drug Metab Dispos; 2010 Feb; 38(2):232-40. PubMed ID: 19875500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adenosine Triphosphate-Sensitive Potassium Channel Kir Subunits Implicated in Cardioprotection by Diazoxide.
    Henn MC; Janjua MB; Kanter EM; Makepeace CM; Schuessler RB; Nichols CG; Lawton JS
    J Am Heart Assoc; 2015 Aug; 4(8):e002016. PubMed ID: 26304939
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane.
    Er F; Michels G; Gassanov N; Rivero F; Hoppe UC
    Circulation; 2004 Nov; 110(19):3100-7. PubMed ID: 15520315
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidences for an ATP-sensitive potassium channel (KATP) in muscle and fat body mitochondria of insect.
    Slocinska M; Lubawy J; Jarmuszkiewicz W; Rosinski G
    J Insect Physiol; 2013 Nov; 59(11):1125-32. PubMed ID: 23973818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [The influence of the fluorine-containing activators of mitochondrial adenosine triphosphate sensitive potassium channels on the oxidative phosphorilation].
    Pyvovar SM; Korzhov VI; Strutyns'kyĭ RB; Iahupol's'kyĭ LM; Moĭbenko OO
    Fiziol Zh (1994); 2006; 52(3):25-33. PubMed ID: 16909753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.