These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 24055077)

  • 1. Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies.
    Wu HQ; Yan ZH; Chen WX; He QQ; Chen FE; De Clercq E; Balzarini J; Daelemans D; Pannecouque C
    Bioorg Med Chem; 2013 Nov; 21(21):6477-83. PubMed ID: 24055077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.
    Ragno R; Mai A; Sbardella G; Artico M; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; La Colla P
    J Med Chem; 2004 Feb; 47(4):928-34. PubMed ID: 14761194
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and SAR of naphthyl-substituted Diarylpyrimidines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Liang YH; Feng XQ; Zeng ZS; Chen FE; Balzarini J; Pannecouque C; De Clercq E
    ChemMedChem; 2009 Sep; 4(9):1537-45. PubMed ID: 19591191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural modifications of CH(OH)-DAPYs as new HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Yan ZH; Huang XY; Wu HQ; Chen WX; He QQ; Chen FE; De Clercq E; Pannecouque C
    Bioorg Med Chem; 2014 Apr; 22(8):2535-41. PubMed ID: 24680058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 6-substituted 5-alkyl-2-(phenylaminocarbonylmethylthio)pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs.
    Yu M; Li Z; Liu S; Fan E; Pannecouque C; De Clercq E; Liu X
    ChemMedChem; 2011 May; 6(5):826-33. PubMed ID: 21322110
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel diarylpyrimidines as potent HIV NNRTIs via a structure-guided core-refining approach.
    Li X; Chen W; Tian Y; Liu H; Zhan P; De Clercq E; Pannecouque C; Balzarini J; Liu X
    Eur J Med Chem; 2014 Jun; 80():112-21. PubMed ID: 24769349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure-activity relationship of novel diarylpyrimidines with hydromethyl linker (CH(OH)-DAPYs) as HIV-1 NNRTIs.
    Gu SX; He QQ; Yang SQ; Ma XD; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    Bioorg Med Chem; 2011 Sep; 19(17):5117-24. PubMed ID: 21824782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and anti-HIV activity of aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as potent non-nucleoside reverse transcriptase inhibitors.
    Ma XD; Yang SQ; Gu SX; He QQ; Chen FE; De Clercq E; Balzarini J; Pannecouque C
    ChemMedChem; 2011 Dec; 6(12):2225-32. PubMed ID: 21990112
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Wu HQ; Yao J; He QQ; Chen WX; Chen FE; Pannecouque C; De Clercq E; Daelemans D
    Bioorg Med Chem; 2015 Feb; 23(3):624-31. PubMed ID: 25537532
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity.
    Manetti F; Esté JA; Clotet-Codina I; Armand-Ugón M; Maga G; Crespan E; Cancio R; Mugnaini C; Bernardini C; Togninelli A; Carmi C; Alongi M; Petricci E; Massa S; Corelli F; Botta M
    J Med Chem; 2005 Dec; 48(25):8000-8. PubMed ID: 16335924
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of a new series of modified CH-diarylpyrimidines as drug-resistant HIV non-nucleoside reverse transcriptase inhibitors.
    Meng G; Liu Y; Zheng A; Chen F; Chen W; De Clercq E; Pannecouque C; Balzarini J
    Eur J Med Chem; 2014 Jul; 82():600-11. PubMed ID: 24952305
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs.
    Gu SX; Yang SQ; He QQ; Ma XD; Chen FE; Dai HF; Clercq ED; Balzarini J; Pannecouque C
    Bioorg Med Chem; 2011 Dec; 19(23):7093-9. PubMed ID: 22037050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
    Chen X; Liu X; Meng Q; Wang D; Liu H; De Clercq E; Pannecouque C; Balzarini J; Liu X
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6593-7. PubMed ID: 24239481
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs.
    Zhan P; Li X; Li Z; Chen X; Tian Y; Chen W; Liu X; Pannecouque C; De Clercq E
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7155-62. PubMed ID: 23084898
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Mai A; Sbardella G; Artico M; Ragno R; Massa S; Novellino E; Greco G; Lavecchia A; Musiu C; La Colla M; Murgioni C; La Colla P; Loddo R
    J Med Chem; 2001 Aug; 44(16):2544-54. PubMed ID: 11472208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of 3-benzyloxy-linked pyrimidinylphenylamine derivatives as potent HIV-1 NNRTIs.
    Rai D; Chen W; Tian Y; Chen X; Zhan P; De Clercq E; Pannecouque C; Balzarini J; Liu X
    Bioorg Med Chem; 2013 Dec; 21(23):7398-405. PubMed ID: 24134904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
    Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
    Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dihydro-alkoxyl-benzyl-oxopyrimidine derivatives (DABOs) as non-nucleoside reverse transcriptase inhibitors: an update review (2001-2011).
    Yang S; Chen FE; De Clercq E
    Curr Med Chem; 2012; 19(2):152-62. PubMed ID: 22320294
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Follow on-based optimization of the biphenyl-DAPYs as HIV-1 nonnucleoside reverse transcriptase inhibitors against the wild-type and mutant strains.
    Sang Y; Han S; Han S; Pannecouque C; De Clercq E; Zhuang C; Chen F
    Bioorg Chem; 2019 Aug; 89():102974. PubMed ID: 31102693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and anti-HIV activity of 2-naphthyl substituted DAPY analogues as non-nucleoside reverse transcriptase inhibitors.
    Liang YH; He QQ; Zeng ZS; Liu ZQ; Feng XQ; Chen FE; Balzarini J; Pannecouque C; Clercq ED
    Bioorg Med Chem; 2010 Jul; 18(13):4601-5. PubMed ID: 20570527
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.