BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 24055854)

  • 21. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP; den Braver MW; Baze A; Decorde J; Fonsi M; Bachellier P; Vermeulen NPE; Commandeur JNM; Richert L; Vos JC
    Eur J Pharm Sci; 2017 Nov; 109():96-110. PubMed ID: 28778465
    [TBL] [Abstract][Full Text] [Related]  

  • 22. UDP-glucuronosyltransferase 1A1 is the principal enzyme responsible for etoposide glucuronidation in human liver and intestinal microsomes: structural characterization of phenolic and alcoholic glucuronides of etoposide and estimation of enzyme kinetics.
    Wen Z; Tallman MN; Ali SY; Smith PC
    Drug Metab Dispos; 2007 Mar; 35(3):371-80. PubMed ID: 17151191
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Metabolism of the c-Fos/activator protein-1 inhibitor T-5224 by multiple human UDP-glucuronosyltransferase isoforms.
    Uchihashi S; Fukumoto H; Onoda M; Hayakawa H; Ikushiro S; Sakaki T
    Drug Metab Dispos; 2011 May; 39(5):803-13. PubMed ID: 21346002
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry.
    Badée J; Qiu N; Parrott N; Collier AC; Schmidt S; Fowler S
    Drug Metab Dispos; 2019 Feb; 47(2):124-134. PubMed ID: 30478159
    [TBL] [Abstract][Full Text] [Related]  

  • 26. In vitrometabolic mapping of neobavaisoflavone in human cytochromes P450 and UDP-glucuronosyltransferase enzymes by ultra high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.
    Xu J; Li M; Yao Z; Zhang Y; Li S; Hu L; Qin Z; Gonzalez FJ; Yao X
    J Pharm Biomed Anal; 2018 Sep; 158():351-360. PubMed ID: 29933228
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Substrate-dependent modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1) by propofol in recombinant human UGT1A1 and human liver microsomes.
    Mano Y; Usui T; Kamimura H
    Basic Clin Pharmacol Toxicol; 2007 Sep; 101(3):211-4. PubMed ID: 17697043
    [TBL] [Abstract][Full Text] [Related]  

  • 28. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
    Kim JH; Kwon SS; Kong TY; Cheong JC; Kim HS; In MK; Lee HS
    Molecules; 2017 Mar; 22(3):. PubMed ID: 28287454
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes.
    Tachibana M; Tanaka M; Masubuchi Y; Horie T
    Drug Metab Dispos; 2005 Jun; 33(6):803-11. PubMed ID: 15769885
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Involvement of multiple UDP-glucuronosyltransferase 1A isoforms in glucuronidation of 5-(4'-hydroxyphenyl)-5-phenylhydantoin in human liver microsomes.
    Nakajima M; Sakata N; Ohashi N; Kume T; Yokoi T
    Drug Metab Dispos; 2002 Nov; 30(11):1250-6. PubMed ID: 12386132
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Glucuronidation of capsaicin by liver microsomes and expressed UGT enzymes: reaction kinetics, contribution of individual enzymes and marked species differences.
    Sun H; Wang H; Liu H; Zhang X; Wu B
    Expert Opin Drug Metab Toxicol; 2014 Oct; 10(10):1325-36. PubMed ID: 25219630
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction.
    Meng F; Li Y; He G; Ge G; Liu S
    Fitoterapia; 2017 Mar; 117():118-125. PubMed ID: 27915055
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
    Chen A; Zhou X; Cheng Y; Tang S; Liu M; Wang X
    Toxicol Lett; 2018 Oct; 295():379-389. PubMed ID: 30036684
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5'-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography-Tandem Mass Spectrometry.
    Lee B; Ji HK; Lee T; Liu KH
    Drug Metab Dispos; 2015 Jul; 43(7):1137-46. PubMed ID: 25904760
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin.
    Hanioka N; Ozawa S; Jinno H; Ando M; Saito Y; Sawada J
    Xenobiotica; 2001 Oct; 31(10):687-99. PubMed ID: 11695848
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Accurate identification of UDP-glucuronosyltransferase 1A1 (UGT1A1) inhibitors using UGT1A1-overexpressing HeLa cells.
    Sun H; Zhou X; Wu B
    Xenobiotica; 2015; 45(11):945-53. PubMed ID: 26068529
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H; Kume T
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [Investigation of metabolic kinetics and reaction phenotyping of ligustrazin by using liver microsomes and recombinant human enzymes].
    Tan Y; Zhuang XM; Shen GL; Li H; Gao Y
    Yao Xue Xue Bao; 2014 Mar; 49(3):374-9. PubMed ID: 24961110
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Evaluation of mutation effects on UGT1A1 activity toward 17beta-estradiol using liquid chromatography-tandem mass spectrometry.
    Wada K; Takeuchi A; Saiki K; Sutomo R; Van Rostenberghe H; Yusoff NM; Laosombat V; Sadewa AH; Talib NA; Yusoff S; Lee MJ; Ayaki H; Nakamura H; Matsuo M; Nishio H
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Jun; 838(1):9-14. PubMed ID: 16504606
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.