BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 24056399)

  • 1. A conserved motif flags acyl carrier proteins for β-branching in polyketide synthesis.
    Haines AS; Dong X; Song Z; Farmer R; Williams C; Hothersall J; Płoskoń E; Wattana-Amorn P; Stephens ER; Yamada E; Gurney R; Takebayashi Y; Masschelein J; Cox RJ; Lavigne R; Willis CL; Simpson TJ; Crosby J; Winn PJ; Thomas CM; Crump MP
    Nat Chem Biol; 2013 Nov; 9(11):685-692. PubMed ID: 24056399
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
    Maloney FP; Gerwick L; Gerwick WH; Sherman DH; Smith JL
    Proc Natl Acad Sci U S A; 2016 Sep; 113(37):10316-21. PubMed ID: 27573844
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.
    Evans SE; Williams C; Arthur CJ; Burston SG; Simpson TJ; Crosby J; Crump MP
    Chembiochem; 2008 Oct; 9(15):2424-32. PubMed ID: 18770515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure, function and dynamics in acyl carrier proteins.
    Farmer R; Thomas CM; Winn PJ
    PLoS One; 2019; 14(7):e0219435. PubMed ID: 31291335
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain.
    Barajas JF; Finzel K; Valentic TR; Shakya G; Gamarra N; Martinez D; Meier JL; Vagstad AL; Newman AG; Townsend CA; Burkart MD; Tsai SC
    Angew Chem Int Ed Engl; 2016 Oct; 55(42):13005-13009. PubMed ID: 27653519
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.
    Weissman KJ; Hong H; Popovic B; Meersman F
    Chem Biol; 2006 Jun; 13(6):625-36. PubMed ID: 16793520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis.
    Miyanaga A; Ouchi R; Ishikawa F; Goto E; Tanabe G; Kudo F; Eguchi T
    J Am Chem Soc; 2018 Jun; 140(25):7970-7978. PubMed ID: 29870659
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase.
    Buchholz TJ; Rath CM; Lopanik NB; Gardner NP; Håkansson K; Sherman DH
    Chem Biol; 2010 Oct; 17(10):1092-100. PubMed ID: 21035732
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probing the structure and function of acyl carrier proteins to unlock the strategic redesign of type II polyketide biosynthetic pathways.
    Sulpizio A; Crawford CEW; Koweek RS; Charkoudian LK
    J Biol Chem; 2021; 296():100328. PubMed ID: 33493513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G; Anand S; Mohanty D
    J Biomol Struct Dyn; 2013; 31(1):17-29. PubMed ID: 22803697
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins.
    Cho YI; Armstrong CL; Sulpizio A; Acheampong KK; Banks KN; Bardhan O; Churchill SJ; Connolly-Sporing AE; Crawford CEW; Cruz Parrilla PL; Curtis SM; De La Ossa LM; Epstein SC; Farrehi CJ; Hamrick GS; Hillegas WJ; Kang A; Laxton OC; Ling J; Matsumura SM; Merino VM; Mukhtar SH; Shah NJ; Londergan CH; Daly CA; Kokona B; Charkoudian LK
    Biochemistry; 2022 Feb; 61(4):217-227. PubMed ID: 35073057
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Solution structure of B. subtilis acyl carrier protein.
    Xu GY; Tam A; Lin L; Hixon J; Fritz CC; Powers R
    Structure; 2001 Apr; 9(4):277-87. PubMed ID: 11525165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D; Katsuyama Y; Horiuchi M; Fushinobu S; Chen A; Davis TD; Burkart MD; Ohnishi Y
    Nat Chem Biol; 2020 Jul; 16(7):776-782. PubMed ID: 32367018
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein.
    Li Q; Khosla C; Puglisi JD; Liu CW
    Biochemistry; 2003 Apr; 42(16):4648-57. PubMed ID: 12705828
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mapping a ketosynthase:acyl carrier protein binding interface via unnatural amino acid-mediated photo-cross-linking.
    Ye Z; Williams GJ
    Biochemistry; 2014 Dec; 53(48):7494-502. PubMed ID: 25427130
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational analysis of the myxovirescin biosynthetic gene cluster reveals novel insights into the functional elaboration of polyketide backbones.
    Simunovic V; Müller R
    Chembiochem; 2007 Jul; 8(11):1273-80. PubMed ID: 17583882
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.
    Bruegger J; Haushalter RW; Vagstad AL; Shakya G; Mih N; Townsend CA; Burkart MD; Tsai SC
    Chem Biol; 2013 Sep; 20(9):1135-46. PubMed ID: 23993461
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).
    Evans SE; Williams C; Arthur CJ; Płoskoń E; Wattana-amorn P; Cox RJ; Crosby J; Willis CL; Simpson TJ; Crump MP
    J Mol Biol; 2009 Jun; 389(3):511-28. PubMed ID: 19361520
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Knockout of the regulatory site of 3-ketoacyl-ACP synthase III enhances short- and medium-chain acyl-ACP synthesis.
    Abbadi A; Brummel M; Spener F
    Plant J; 2000 Oct; 24(1):1-9. PubMed ID: 11029699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.