BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 24067654)

  • 1. Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.
    Tian Y; Chang JC; Fan EY; Flajolet M; Greengard P
    Proc Natl Acad Sci U S A; 2013 Oct; 110(42):17071-6. PubMed ID: 24067654
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The convergence of endosomal and autophagosomal pathways: implications for APP-CTF degradation.
    Tian Y; Chang JC; Greengard P; Flajolet M
    Autophagy; 2014 Apr; 10(4):694-6. PubMed ID: 24447917
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis.
    Xiao Q; Gil SC; Yan P; Wang Y; Han S; Gonzales E; Perez R; Cirrito JR; Lee JM
    J Biol Chem; 2012 Jun; 287(25):21279-89. PubMed ID: 22539346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease.
    Thomas RS; Henson A; Gerrish A; Jones L; Williams J; Kidd EJ
    BMC Neurosci; 2016 Jul; 17(1):50. PubMed ID: 27430330
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of PTB domain containing adaptor proteins on PICALM-mediated APP endocytosis and localization.
    Merthan L; Haller A; Thal DR; von Einem B; von Arnim CAF
    Biochem J; 2019 Jul; 476(14):2093-2109. PubMed ID: 31300465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.
    Tian Y; Bustos V; Flajolet M; Greengard P
    FASEB J; 2011 Jun; 25(6):1934-42. PubMed ID: 21368103
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PICALM and Alzheimer's Disease: An Update and Perspectives.
    Ando K; Nagaraj S; Küçükali F; de Fisenne MA; Kosa AC; Doeraene E; Lopez Gutierrez L; Brion JP; Leroy K
    Cells; 2022 Dec; 11(24):. PubMed ID: 36552756
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.
    Salminen A; Kaarniranta K; Kauppinen A; Ojala J; Haapasalo A; Soininen H; Hiltunen M
    Prog Neurobiol; 2013; 106-107():33-54. PubMed ID: 23827971
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation.
    Cai CZ; Yang C; Zhuang XX; Yuan NN; Wu MY; Tan JQ; Song JX; Cheung KH; Su H; Wang YT; Tang BS; Behrends C; Durairajan SSK; Yue Z; Li M; Lu JH
    Autophagy; 2021 May; 17(5):1112-1130. PubMed ID: 32543313
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
    Maesako M; Uemura M; Tashiro Y; Sasaki K; Watanabe K; Noda Y; Ueda K; Asada-Utsugi M; Kubota M; Okawa K; Ihara M; Shimohama S; Uemura K; Kinoshita A
    PLoS One; 2015; 10(9):e0131199. PubMed ID: 26414661
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Real-time heterogeneity of supramolecular assembly of amyloid precursor protein is modulated by an endocytic risk factor PICALM.
    Belapurkar V; Mahadeva Swamy HS; Singh N; Kedia S; Setty SRG; Jose M; Nair D
    Cell Mol Life Sci; 2023 Sep; 80(10):295. PubMed ID: 37726569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gypenoside XVII Enhances Lysosome Biogenesis and Autophagy Flux and Accelerates Autophagic Clearance of Amyloid-β through TFEB Activation.
    Meng X; Luo Y; Liang T; Wang M; Zhao J; Sun G; Sun X
    J Alzheimers Dis; 2016 Apr; 52(3):1135-50. PubMed ID: 27060963
    [TBL] [Abstract][Full Text] [Related]  

  • 13. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.
    Maulik M; Peake K; Chung J; Wang Y; Vance JE; Kar S
    Hum Mol Genet; 2015 Dec; 24(24):7132-50. PubMed ID: 26433932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of amyloid precursor protein processing by the Beclin 1 complex.
    Jaeger PA; Pickford F; Sun CH; Lucin KM; Masliah E; Wyss-Coray T
    PLoS One; 2010 Jun; 5(6):e11102. PubMed ID: 20559548
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distribution and expression of picalm in Alzheimer disease.
    Baig S; Joseph SA; Tayler H; Abraham R; Owen MJ; Williams J; Kehoe PG; Love S
    J Neuropathol Exp Neurol; 2010 Oct; 69(10):1071-7. PubMed ID: 20838239
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TFEB-mediated Enhancement of the Autophagy-lysosomal Pathway Dually Modulates the Process of Amyloid β-Protein Generation in Neurons.
    Yamamoto F; Taniguchi K; Mamada N; Tamaoka A; Kametani F; Lakshmana MK; Araki W
    Neuroscience; 2019 Mar; 402():11-22. PubMed ID: 30677488
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer's disease.
    Wang BJ; Her GM; Hu MK; Chen YW; Tung YT; Wu PY; Hsu WM; Lee H; Jin LW; Hwang SL; Chen RP; Huang CJ; Liao YF
    Proc Natl Acad Sci U S A; 2017 Apr; 114(15):E3129-E3138. PubMed ID: 28351972
    [TBL] [Abstract][Full Text] [Related]  

  • 18. β‑asarone modulates Beclin‑1, LC3 and p62 expression to attenuate Aβ40 and Aβ42 levels in APP/PS1 transgenic mice with Alzheimer's disease.
    Deng M; Huang L; Zhong X
    Mol Med Rep; 2020 May; 21(5):2095-2102. PubMed ID: 32186763
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome.
    Hein LK; Apaja PM; Hattersley K; Grose RH; Xie J; Proud CG; Sargeant TJ
    Biochim Biophys Acta Mol Cell Res; 2017 Oct; 1864(10):1554-1565. PubMed ID: 28641977
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cilostazol Upregulates Autophagy via SIRT1 Activation: Reducing Amyloid-β Peptide and APP-CTFβ Levels in Neuronal Cells.
    Lee HR; Shin HK; Park SY; Kim HY; Bae SS; Lee WS; Rhim BY; Hong KW; Kim CD
    PLoS One; 2015; 10(8):e0134486. PubMed ID: 26244661
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.