These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 24069881)

  • 1. A new strategy to improve the metabolic stability of lactone: discovery of (20S,21S)-21-fluorocamptothecins as novel, hydrolytically stable topoisomerase I inhibitors.
    Miao Z; Zhu L; Dong G; Zhuang C; Wu Y; Wang S; Guo Z; Liu Y; Wu S; Zhu S; Fang K; Yao J; Li J; Sheng C; Zhang W
    J Med Chem; 2013 Oct; 56(20):7902-10. PubMed ID: 24069881
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and preliminary bioevaluation of novel E-ring modified acetal analog of camptothecin as cytotoxic agents.
    Zhu L; Zhuang C; Lei N; Guo Z; Sheng C; Dong G; Wang S; Zhang Y; Yao J; Miao Z; Zhang W
    Eur J Med Chem; 2012 Oct; 56():1-9. PubMed ID: 23084702
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of new homocamptothecin analogs.
    Luo Y; Yu S; Tong L; Huang Q; Lu W; Chen Y
    Eur J Med Chem; 2012 Aug; 54():281-6. PubMed ID: 22647222
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two novel camptothecin derivatives inhibit colorectal cancer proliferation via induction of cell cycle arrest and apoptosis in vitro and in vivo.
    Du H; Huang Y; Hou X; Quan X; Jiang J; Wei X; Liu Y; Li H; Wang P; Zhan M; Ai X; Lu L; Yuan S; Sun L
    Eur J Pharm Sci; 2018 Oct; 123():546-559. PubMed ID: 30118848
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents.
    Huang Q; Wang L; Lu W
    Eur J Med Chem; 2013 May; 63():746-57. PubMed ID: 23578545
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antitumor activity of the hexacyclic camptothecin derivatives.
    Gao H; Zhang X; Chen Y; Shen H; Pang T; Sun J; Xu C; Ding J; Li C; Lu W
    Bioorg Med Chem Lett; 2005 Jul; 15(13):3233-6. PubMed ID: 15913996
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
    J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
    Zhang C; Li S; Ji L; Liu S; Li Z; Li S; Meng X
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4693-6. PubMed ID: 26384290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 9-(heteroarylmethylidene)amino derivatives of homocamptothecin with biological activities.
    Guo W; Miao Z; Sheng C; Yao J; Liu W; Zhu L; Zhang Y; Cheng P; Dong G; Zhuang C; Zhang W
    Chem Biodivers; 2011 Jul; 8(7):1266-73. PubMed ID: 21766447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
    Zhu L; Zhang X; Lei N; Liu W; Miao Z; Zhuang C; Sheng C; Guo W; Dong G; Yao J; Cheng P; Zhang W
    Chem Biodivers; 2012 Jun; 9(6):1084-94. PubMed ID: 22700227
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
    Liu W; Zhu L; Guo W; Zhuang C; Zhang Y; Sheng C; Cheng P; Yao J; Wang W; Dong G; Wang S; Miao Z; Zhang W
    Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of novel homocamptothecins conjugating with dihydropyrimidine derivatives as potent topoisomerase I inhibitors.
    Zhu L; Cheng P; Lei N; Yao J; Sheng C; Zhuang C; Guo W; Liu W; Zhang Y; Dong G; Wang S; Miao Z; Zhang W
    Arch Pharm (Weinheim); 2011 Nov; 344(11):726-34. PubMed ID: 21956522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationship study of 16 a-thiocamptothecins: an integrated in vitro and in silico approach.
    Samorì C; Beretta GL; Varchi G; Guerrini A; Di Micco S; Basili S; Bifulco G; Riccio R; Moro S; Bombardelli E; Zunino F; Fontana G
    ChemMedChem; 2010 Dec; 5(12):2006-15. PubMed ID: 21069656
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Novel Camptothecin Derivative 3j Inhibits Nsclc Proliferation Via Induction of Cell Cycle Arrest By Topo I-Mediated DNA Damage.
    Liu Y; Zhang J; Feng S; Zhao T; Li Z; Wang L; Wang P; Du H; Yuan S; Sun L
    Anticancer Agents Med Chem; 2019; 19(3):365-374. PubMed ID: 30523769
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents.
    Wang MJ; Liu YQ; Chang LC; Wang CY; Zhao YL; Zhao XB; Qian K; Nan X; Yang L; Yang XM; Hung HY; Yang JS; Kuo DH; Goto M; Morris-Natschke SL; Pan SL; Teng CM; Kuo SC; Wu TS; Wu YC; Lee KH
    J Med Chem; 2014 Jul; 57(14):6008-18. PubMed ID: 25003995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
    Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Camptothecin-psammaplin A hybrids as topoisomerase I and HDAC dual-action inhibitors.
    Cincinelli R; Musso L; Artali R; Guglielmi M; Bianchino E; Cardile F; Colelli F; Pisano C; Dallavalle S
    Eur J Med Chem; 2018 Jan; 143():2005-2014. PubMed ID: 29150335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Biological Evaluation of 10-Substituted Camptothecin Derivatives with Improved Water Solubility and Activity.
    Yang XY; Zhao HY; Lei H; Yuan B; Mao S; Xin M; Zhang SQ
    ChemMedChem; 2021 Mar; 16(6):1000-1010. PubMed ID: 33241878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, Synthesis and Biological Activity of (20S,21S)-7-Cyclohexyl-21-fluorocamptothecin Carbamates as Potential Antitumor Agents.
    Ma H; Chen B; Wang Y; Wang C; Yao J; Zhang W; Miao Z
    Chem Biodivers; 2020 Jul; 17(7):e2000068. PubMed ID: 32342605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Semi-synthesis and biological activity of gamma-lactones analogs of camptothecin.
    Li M; Tang W; Zeng F; Lou L; You T
    Bioorg Med Chem Lett; 2008 Dec; 18(24):6441-3. PubMed ID: 18986807
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.