These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 24070051)

  • 1. Investigation into temperature-induced aggregation of an antibody drug conjugate.
    Beckley NS; Lazzareschi KP; Chih HW; Sharma VK; Flores HL
    Bioconjug Chem; 2013 Oct; 24(10):1674-83. PubMed ID: 24070051
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of cysteine-linked conjugation profiles of immunoglobulin G1 and immunoglobulin G2 antibody-drug conjugates.
    Wiggins B; Liu-Shin L; Yamaguchi H; Ratnaswamy G
    J Pharm Sci; 2015 Apr; 104(4):1362-72. PubMed ID: 25631158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Auristatin antibody drug conjugate physical instability and the role of drug payload.
    Adem YT; Schwarz KA; Duenas E; Patapoff TW; Galush WJ; Esue O
    Bioconjug Chem; 2014 Apr; 25(4):656-64. PubMed ID: 24559399
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of drug conjugation on pharmacokinetics and tissue distribution of anti-STEAP1 antibody-drug conjugates in rats.
    Boswell CA; Mundo EE; Zhang C; Bumbaca D; Valle NR; Kozak KR; Fourie A; Chuh J; Koppada N; Saad O; Gill H; Shen BQ; Rubinfeld B; Tibbitts J; Kaur S; Theil FP; Fielder PJ; Khawli LA; Lin K
    Bioconjug Chem; 2011 Oct; 22(10):1994-2004. PubMed ID: 21913715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo drug-linker stability of an anti-CD30 dipeptide-linked auristatin immunoconjugate.
    Sanderson RJ; Hering MA; James SF; Sun MM; Doronina SO; Siadak AW; Senter PD; Wahl AF
    Clin Cancer Res; 2005 Jan; 11(2 Pt 1):843-52. PubMed ID: 15701875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization and Higher-Order Structure Assessment of an Interchain Cysteine-Based ADC: Impact of Drug Loading and Distribution on the Mechanism of Aggregation.
    Guo J; Kumar S; Chipley M; Marcq O; Gupta D; Jin Z; Tomar DS; Swabowski C; Smith J; Starkey JA; Singh SK
    Bioconjug Chem; 2016 Mar; 27(3):604-15. PubMed ID: 26829368
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Native intact mass determination of antibodies conjugated with monomethyl Auristatin E and F at interchain cysteine residues.
    Valliere-Douglass JF; McFee WA; Salas-Solano O
    Anal Chem; 2012 Mar; 84(6):2843-9. PubMed ID: 22384990
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bridging disulfides for stable and defined antibody drug conjugates.
    Badescu G; Bryant P; Bird M; Henseleit K; Swierkosz J; Parekh V; Tommasi R; Pawlisz E; Jurlewicz K; Farys M; Camper N; Sheng X; Fisher M; Grygorash R; Kyle A; Abhilash A; Frigerio M; Edwards J; Godwin A
    Bioconjug Chem; 2014 Jun; 25(6):1124-36. PubMed ID: 24791606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influence of disulfide bond isoforms on drug conjugation sites in cysteine-linked IgG2 antibody-drug conjugates.
    Liu-Shin L; Fung A; Malhotra A; Ratnaswamy G
    MAbs; 2018; 10(4):583-595. PubMed ID: 29436897
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers.
    Ohri R; Bhakta S; Fourie-O'Donohue A; Dela Cruz-Chuh J; Tsai SP; Cook R; Wei B; Ng C; Wong AW; Bos AB; Farahi F; Bhakta J; Pillow TH; Raab H; Vandlen R; Polakis P; Liu Y; Erickson H; Junutula JR; Kozak KR
    Bioconjug Chem; 2018 Feb; 29(2):473-485. PubMed ID: 29425028
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transglutaminase-based chemo-enzymatic conjugation approach yields homogeneous antibody-drug conjugates.
    Dennler P; Chiotellis A; Fischer E; Brégeon D; Belmant C; Gauthier L; Lhospice F; Romagne F; Schibli R
    Bioconjug Chem; 2014 Mar; 25(3):569-78. PubMed ID: 24483299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cathepsin B Cleavage of vcMMAE-Based Antibody-Drug Conjugate Is Not Drug Location or Monoclonal Antibody Carrier Specific.
    Gikanga B; Adeniji NS; Patapoff TW; Chih HW; Yi L
    Bioconjug Chem; 2016 Apr; 27(4):1040-9. PubMed ID: 26914498
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biophysical Properties and Heating-Induced Aggregation of Lysine-Conjugated Antibody-Drug Conjugates.
    Gandhi AV; Arlotta KJ; Chen HN; Owen SC; Carpenter JF
    J Pharm Sci; 2018 Jul; 107(7):1858-1869. PubMed ID: 29626535
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural characterization of a monomethylauristatin-E based ADC that contains 8 drugs conjugated at interchain cysteine residues.
    Chiu D; Pan L; Fay L; Eakin C; Valliere-Douglass J
    J Pharm Biomed Anal; 2021 Oct; 205():114309. PubMed ID: 34403866
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Properties of Cysteine-Conjugated Antibody-Drug Conjugates Are Impacted by the IgG Subclass.
    Datta-Mannan A; Choi H; Stokell D; Tang J; Murphy A; Wrobleski A; Feng Y
    AAPS J; 2018 Sep; 20(6):103. PubMed ID: 30255287
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody-drug conjugate (ADC).
    Nunes JP; Morais M; Vassileva V; Robinson E; Rajkumar VS; Smith ME; Pedley RB; Caddick S; Baker JR; Chudasama V
    Chem Commun (Camb); 2015 Jul; 51(53):10624-7. PubMed ID: 26051118
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate.
    Mohamed Amar IA; Huvelle S; Douez E; Letast S; Henrion S; Viaud-Massuard MC; Aubrey N; Allard-Vannier E; Joubert N; Denevault-Sabourin C
    Eur J Med Chem; 2022 Feb; 229():114063. PubMed ID: 34974337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides.
    Christie RJ; Fleming R; Bezabeh B; Woods R; Mao S; Harper J; Joseph A; Wang Q; Xu ZQ; Wu H; Gao C; Dimasi N
    J Control Release; 2015 Dec; 220(Pt B):660-70. PubMed ID: 26387744
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment of physical stability of an antibody drug conjugate by higher order structure analysis: impact of thiol- maleimide chemistry.
    Guo J; Kumar S; Prashad A; Starkey J; Singh SK
    Pharm Res; 2014 Jul; 31(7):1710-23. PubMed ID: 24464270
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of attachment site on stability of cleavable antibody drug conjugates.
    Dorywalska M; Strop P; Melton-Witt JA; Hasa-Moreno A; Farias SE; Galindo Casas M; Delaria K; Lui V; Poulsen K; Loo C; Krimm S; Bolton G; Moine L; Dushin R; Tran TT; Liu SH; Rickert M; Foletti D; Shelton DL; Pons J; Rajpal A
    Bioconjug Chem; 2015 Apr; 26(4):650-9. PubMed ID: 25643134
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.