These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 24073415)

  • 1. Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study.
    Tricarico PM; Kleiner G; Piscianz E; Zanin V; Monasta L; Crovella S; Marcuzzi A
    Biomed Res Int; 2013; 2013():715465. PubMed ID: 24073415
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The inhibition of mevalonate pathway induces upregulation of NALP3 expression: new insight in the pathogenesis of mevalonate kinase deficiency.
    Pontillo A; Paoluzzi E; Crovella S
    Eur J Hum Genet; 2010 Jul; 18(7):844-7. PubMed ID: 20179743
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.
    Marcuzzi A; De Leo L; Decorti G; Crovella S; Tommasini A; Pontillo A
    Pediatr Res; 2011 Jul; 70(1):78-82. PubMed ID: 21430599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Block of the mevalonate pathway triggers oxidative and inflammatory molecular mechanisms modulated by exogenous isoprenoid compounds.
    Tricarico PM; Kleiner G; Valencic E; Campisciano G; Girardelli M; Crovella S; Knowles A; Marcuzzi A
    Int J Mol Sci; 2014 Apr; 15(4):6843-56. PubMed ID: 24758928
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Geraniol rescues inflammation in cellular and animal models of mevalonate kinase deficiency.
    Marcuzzi A; Crovella S; Pontillo A
    In Vivo; 2011; 25(1):87-92. PubMed ID: 21282739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.
    De Leo L; Marcuzzi A; Decorti G; Tommasini A; Crovella S; Pontillo A
    Pharmacol Res; 2010 Jun; 61(6):506-10. PubMed ID: 20206266
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency.
    Munoz MA; Skinner OP; Masle-Farquhar E; Jurczyluk J; Xiao Y; Fletcher EK; Kristianto E; Hodson MP; O'Donoghue SI; Kaur S; Brink R; Zahra DG; Deenick EK; Perry KA; Robertson AA; Mehr S; Hissaria P; Mulders-Manders CM; Simon A; Rogers MJ
    J Clin Invest; 2022 Oct; 132(19):. PubMed ID: 36189795
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compromised Protein Prenylation as Pathogenic Mechanism in Mevalonate Kinase Deficiency.
    Politiek FA; Waterham HR
    Front Immunol; 2021; 12():724991. PubMed ID: 34539662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific increase in caspase-1 activity and secretion of IL-1 family cytokines: a putative link between mevalonate kinase deficiency and inflammation.
    Normand S; Massonnet B; Delwail A; Favot L; Cuisset L; Grateau G; Morel F; Silvain C; Lecron JC
    Eur Cytokine Netw; 2009 Sep; 20(3):101-7. PubMed ID: 19825518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mevalonate Kinase Deficiency and Squalene Synthase Inhibitor (TAK-475): The Balance to Extinguish the Inflammation.
    Rimondi E; Valencic E; Tommasini A; Secchiero P; Melloni E; Marcuzzi A
    Biomolecules; 2021 Sep; 11(10):. PubMed ID: 34680069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Natural isoprenoids inhibit LPS-induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes.
    Marcuzzi A; Tommasini A; Crovella S; Pontillo A
    Int Immunopharmacol; 2010 Jun; 10(6):639-42. PubMed ID: 20304105
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mevalonate kinase deficiency: disclosing the role of mevalonate pathway modulation in inflammation.
    Marcuzzi A; Crovella S; Monasta L; Vecchi Brumatti L; Gattorno M; Frenkel J
    Curr Pharm Des; 2012; 18(35):5746-52. PubMed ID: 22726114
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency.
    Marcuzzi A; Pontillo A; De Leo L; Tommasini A; Decorti G; Not T; Ventura A
    Pediatr Res; 2008 Aug; 64(2):177-82. PubMed ID: 18391837
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A role for geranylgeranylation in interleukin-1beta secretion.
    Mandey SH; Kuijk LM; Frenkel J; Waterham HR
    Arthritis Rheum; 2006 Nov; 54(11):3690-5. PubMed ID: 17075828
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study.
    Kleiner G; Celsi F; Tricarico PM; Zacchigna S; Crovella S; Marcuzzi A
    In Vivo; 2013; 27(6):715-22. PubMed ID: 24292573
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.
    Jurczyluk J; Munoz MA; Skinner OP; Chai RC; Ali N; Palendira U; Quinn JM; Preston A; Tangye SG; Brown AJ; Argent E; Ziegler JB; Mehr S; Rogers MJ
    Immunol Cell Biol; 2016 Nov; 94(10):994-999. PubMed ID: 27377765
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients.
    Marcuzzi A; Zanin V; Kleiner G; Monasta L; Crovella S
    Pediatr Res; 2013 Sep; 74(3):266-71. PubMed ID: 23760140
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alendronate, a double-edged sword acting in the mevalonate pathway.
    Tricarico PM; Girardelli M; Kleiner G; Knowles A; Valencic E; Crovella S; Marcuzzi A
    Mol Med Rep; 2015 Sep; 12(3):4238-4242. PubMed ID: 26096667
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Repositioning of Tak-475 In Mevalonate Kinase Disease: Translating Theory Into Practice.
    Marcuzzi A; Loganes C; Celeghini C; Kleiner G
    Curr Med Chem; 2018; 25(24):2783-2796. PubMed ID: 28901277
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Respiratory deficiency in yeast mevalonate kinase deficient may explain MKD-associate metabolic disorder in humans.
    Santos MMS; Elsztein C; De Souza RB; Paiva SSL; Silva JA; Crovella S; De Morais MA
    Curr Genet; 2018 Aug; 64(4):871-881. PubMed ID: 29374778
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.