BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 24074878)

  • 1. Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
    Diogo EB; Dias GG; Rodrigues BL; Guimarães TT; Valença WO; Camara CA; de Oliveira RN; da Silva MG; Ferreira VF; de Paiva YG; Goulart MO; Menna-Barreto RF; de Castro SL; da Silva Júnior EN
    Bioorg Med Chem; 2013 Nov; 21(21):6337-48. PubMed ID: 24074878
    [TBL] [Abstract][Full Text] [Related]  

  • 2. On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
    da Silva Júnior EN; de Melo IM; Diogo EB; Costa VA; de Souza Filho JD; Valença WO; Camara CA; de Oliveira RN; de Araujo AS; Emery FS; dos Santos MR; de Simone CA; Menna-Barreto RF; de Castro SL
    Eur J Med Chem; 2012 Jun; 52():304-12. PubMed ID: 22483633
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
    da Silva EN; Menna-Barreto RF; Pinto Mdo C; Silva RS; Teixeira DV; de Souza MC; De Simone CA; De Castro SL; Ferreira VF; Pinto AV
    Eur J Med Chem; 2008 Aug; 43(8):1774-80. PubMed ID: 18045742
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and anti-Trypanosoma cruzi activity of new 3-phenylthio-nor-β-lapachone derivatives.
    Cardoso MFDC; Salomão K; Bombaça AC; da Rocha DR; da Silva FC; Cavaleiro JAS; de Castro SL; Ferreira VF
    Bioorg Med Chem; 2015 Aug; 23(15):4763-4768. PubMed ID: 26118339
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.
    da Silva Júnior EN; de Souza MC; Fernandes MC; Menna-Barreto RF; Pinto Mdo C; de Assis Lopes F; de Simone CA; Andrade CK; Pinto AV; Ferreira VF; de Castro SL
    Bioorg Med Chem; 2008 May; 16(9):5030-8. PubMed ID: 18378461
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones.
    Jardim GAM; Silva TL; Goulart MOF; de Simone CA; Barbosa JMC; Salomão K; de Castro SL; Bower JF; da Silva Júnior EN
    Eur J Med Chem; 2017 Aug; 136():406-419. PubMed ID: 28521262
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
    Salas C; Tapia RA; Ciudad K; Armstrong V; Orellana M; Kemmerling U; Ferreira J; Maya JD; Morello A
    Bioorg Med Chem; 2008 Jan; 16(2):668-74. PubMed ID: 18029184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-Phenylaminonaphthoquinones and related compounds: synthesis, trypanocidal and cytotoxic activities.
    Sieveking I; Thomas P; Estévez JC; Quiñones N; Cuéllar MA; Villena J; Espinosa-Bustos C; Fierro A; Tapia RA; Maya JD; López-Muñoz R; Cassels BK; Estévez RJ; Salas CO
    Bioorg Med Chem; 2014 Sep; 22(17):4609-20. PubMed ID: 25127463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
    da Silva EN; Guimarães TT; Menna-Barreto RF; Pinto Mdo C; de Simone CA; Pessoa C; Cavalcanti BC; Sabino JR; Andrade CK; Goulart MO; de Castro SL; Pinto AV
    Bioorg Med Chem; 2010 May; 18(9):3224-30. PubMed ID: 20378360
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease.
    Salas CO; Faúndez M; Morello A; Maya JD; Tapia RA
    Curr Med Chem; 2011; 18(1):144-61. PubMed ID: 21110810
    [TBL] [Abstract][Full Text] [Related]  

  • 11. New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
    Carneiro PF; do Nascimento SB; Pinto AV; Pinto Mdo C; Lechuga GC; Santos DO; dos Santos Júnior HM; Resende JA; Bourguignon SC; Ferreira VF
    Bioorg Med Chem; 2012 Aug; 20(16):4995-5000. PubMed ID: 22795899
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of naphthofuranquinones with activity against Trypanosoma cruzi.
    Silva RS; Costa EM; Trindade UL; Teixeira DV; Pinto Mde C; Santos GL; Malta VR; De Simone CA; Pinto AV; de Castro SL
    Eur J Med Chem; 2006 Apr; 41(4):526-30. PubMed ID: 16500733
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
    Lara LS; Moreira CS; Calvet CM; Lechuga GC; Souza RS; Bourguignon SC; Ferreira VF; Rocha D; Pereira MCS
    Eur J Med Chem; 2018 Jan; 144():572-581. PubMed ID: 29289882
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 1,2,3-Triazole-based analogue of benznidazole displays remarkable activity against Trypanosoma cruzi.
    de Andrade P; Galo OA; Carvalho MR; Lopes CD; Carneiro ZA; Sesti-Costa R; de Melo EB; Silva JS; Carvalho I
    Bioorg Med Chem; 2015 Nov; 23(21):6815-26. PubMed ID: 26476667
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,2,3-triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones.
    da Cruz EH; Hussene CM; Dias GG; Diogo EB; de Melo IM; Rodrigues BL; da Silva MG; Valença WO; Camara CA; de Oliveira RN; de Paiva YG; Goulart MO; Cavalcanti BC; Pessoa C; da Silva Júnior EN
    Bioorg Med Chem; 2014 Mar; 22(5):1608-19. PubMed ID: 24530030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
    Moreira DR; Leite AC; Cardoso MV; Srivastava RM; Hernandes MZ; Rabello MM; da Cruz LF; Ferreira RS; de Simone CA; Meira CS; Guimaraes ET; da Silva AC; dos Santos TA; Pereira VR; Soares MB
    ChemMedChem; 2014 Jan; 9(1):177-88. PubMed ID: 24203393
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, trypanocidal and anti-leishmania activity of new triazole-lapachol and nor-lapachol hybrids.
    Pertino MW; F de la Torre A; Schmeda-Hirschmann G; Vega C; Rolón M; Coronel C; Rojas de Arias A; Leal López K; Carranza-Rosales P; Viveros Valdez E
    Bioorg Chem; 2020 Oct; 103():104122. PubMed ID: 32745754
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.
    Hernandes MZ; Rabello MM; Leite AC; Cardoso MV; Moreira DR; Brondani DJ; Simone CA; Reis LC; Souza MA; Pereira VR; Ferreira RS; McKerrow JH
    Bioorg Med Chem; 2010 Nov; 18(22):7826-35. PubMed ID: 20961766
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi.
    De Souza EM; da Silva PB; Nefertiti AS; Ismail MA; Arafa RK; Tao B; Nixon-Smith CK; Boykin DW; Soeiro MN
    Exp Parasitol; 2011 Feb; 127(2):429-35. PubMed ID: 20971106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trypanocidal activity of synthetic heterocyclic derivatives of active quinones from Tabebuia sp.
    Pinto AV; Pinto CN; Pinto Mdo C; Rita RS; Pezzella CA; de Castro SL
    Arzneimittelforschung; 1997 Jan; 47(1):74-9. PubMed ID: 9037448
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.