183 related articles for article (PubMed ID: 24079514)
1. A novel SERCA inhibitor demonstrates synergy with classic SERCA inhibitors and targets multidrug-resistant AML.
Bleeker NP; Cornea RL; Thomas DD; Xing C
Mol Pharm; 2013 Nov; 10(11):4358-66. PubMed ID: 24079514
[TBL] [Abstract][Full Text] [Related]
2. Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy.
Das SG; Hermanson DL; Bleeker N; Lowman X; Li Y; Kelekar A; Xing C
ACS Chem Biol; 2013 Feb; 8(2):327-35. PubMed ID: 23102022
[TBL] [Abstract][Full Text] [Related]
3. Overexpression of Mcl-1 confers multidrug resistance, whereas topoisomerase IIβ downregulation introduces mitoxantrone-specific drug resistance in acute myeloid leukemia.
Hermanson DL; Das SG; Li Y; Xing C
Mol Pharmacol; 2013 Aug; 84(2):236-43. PubMed ID: 23696245
[TBL] [Abstract][Full Text] [Related]
4. Structure-activity relationship and molecular mechanisms of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and its analogues.
Das SG; Srinivasan B; Hermanson DL; Bleeker NP; Doshi JM; Tang R; Beck WT; Xing C
J Med Chem; 2011 Aug; 54(16):5937-48. PubMed ID: 21780800
[TBL] [Abstract][Full Text] [Related]
5. SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.
Xu SW; Law BYK; Qu SLQ; Hamdoun S; Chen J; Zhang W; Guo JR; Wu AG; Mok SWF; Zhang DW; Xia C; Sugimoto Y; Efferth T; Liu L; Wong VKW
Pharmacol Res; 2020 Mar; 153():104660. PubMed ID: 31982489
[TBL] [Abstract][Full Text] [Related]
6. Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment.
Aridoss G; Zhou B; Hermanson DL; Bleeker NP; Xing C
J Med Chem; 2012 Jun; 55(11):5566-81. PubMed ID: 22582991
[TBL] [Abstract][Full Text] [Related]
7. 4H-Chromene-based anticancer agents towards multi-drug resistant HL60/MX2 human leukemia: SAR at the 4th and 6th positions.
Puppala M; Zhao X; Casemore D; Zhou B; Aridoss G; Narayanapillai S; Xing C
Bioorg Med Chem; 2016 Mar; 24(6):1292-7. PubMed ID: 26867486
[TBL] [Abstract][Full Text] [Related]
8. CXL146, a Novel 4
Bian T; Tagmount A; Vulpe C; Vijendra KC; Xing C
Mol Pharmacol; 2020 Jun; 97(6):402-408. PubMed ID: 32276963
[TBL] [Abstract][Full Text] [Related]
9. Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues.
Das SG; Doshi JM; Tian D; Addo SN; Srinivasan B; Hermanson DL; Xing C
J Med Chem; 2009 Oct; 52(19):5937-49. PubMed ID: 19743858
[TBL] [Abstract][Full Text] [Related]
10. Paradoxical effects of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) activator gingerol on NG115-401L neuronal cells: failure to augment ER Ca(2+) uptake and protect against ER stress-induced cell death.
Zhang C; Bose DD; Thomas DW
Eur J Pharmacol; 2015 Sep; 762():165-73. PubMed ID: 26033206
[TBL] [Abstract][Full Text] [Related]
11. Gene amplification and transcriptional upregulation of the sarco/endoplasmic reticulum Ca2+ transport ATPase in thapsigargin-resistant hamster smooth muscle cells.
Rishi AK; Yu M; Tsai-Wu JJ; Belani CP; Fontana JA; Baker DL; Periasamy M; Hussain A
Nucleic Acids Res; 1998 Oct; 26(19):4529-37. PubMed ID: 9742259
[TBL] [Abstract][Full Text] [Related]
12. Secretory pathway Ca(2+)-ATPase (SPCA1) Ca(2)+ pumps, not SERCAs, regulate complex [Ca(2+)](i) signals in human spermatozoa.
Harper C; Wootton L; Michelangeli F; Lefièvre L; Barratt C; Publicover S
J Cell Sci; 2005 Apr; 118(Pt 8):1673-85. PubMed ID: 15811949
[TBL] [Abstract][Full Text] [Related]
13. Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.
Riganti C; Doublier S; Viarisio D; Miraglia E; Pescarmona G; Ghigo D; Bosia A
Br J Pharmacol; 2009 Apr; 156(7):1054-66. PubMed ID: 19298255
[TBL] [Abstract][Full Text] [Related]
14. Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca2+ ATPase activity in ovarian cancer cells.
Seo JA; Kim B; Dhanasekaran DN; Tsang BK; Song YS
Cancer Lett; 2016 Feb; 371(1):30-7. PubMed ID: 26607901
[TBL] [Abstract][Full Text] [Related]
15. Exploring the Structure-Activity Relationship and Mechanism of a Chromene Scaffold (CXL Series) for Its Selective Antiproliferative Activity toward Multidrug-Resistant Cancer Cells.
Bian T; Chandagirikoppal Vijendra K; Wang Y; Meacham A; Hati S; Cogle CR; Sun H; Xing C
J Med Chem; 2018 Aug; 61(15):6892-6903. PubMed ID: 29995404
[TBL] [Abstract][Full Text] [Related]
16. Inhibitory action of linoleamide and oleamide toward sarco/endoplasmic reticulum Ca
Yamamoto S; Takehara M; Ushimaru M
Biochim Biophys Acta Gen Subj; 2017 Jan; 1861(1 Pt A):3399-3405. PubMed ID: 27595606
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and SERCA activities of structurally simplified cyclopiazonic acid analogues.
Yao S; Gallenkamp D; Wölfel K; Lüke B; Schindler M; Scherkenbeck J
Bioorg Med Chem; 2011 Aug; 19(15):4669-78. PubMed ID: 21719297
[TBL] [Abstract][Full Text] [Related]
18. Enhancement of ATRA-induced cell differentiation by inhibition of calcium accumulation into the endoplasmic reticulum: cross-talk between RAR alpha and calcium-dependent signaling.
Launay S; Giannì M; Diomede L; Machesky LM; Enouf J; Papp B
Blood; 2003 Apr; 101(8):3220-8. PubMed ID: 12515718
[TBL] [Abstract][Full Text] [Related]
19. The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.
Wootton LL; Michelangeli F
J Biol Chem; 2006 Mar; 281(11):6970-6. PubMed ID: 16410239
[TBL] [Abstract][Full Text] [Related]
20. Targeting oncogenic Notch signaling with SERCA inhibitors.
Pagliaro L; Marchesini M; Roti G
J Hematol Oncol; 2021 Jan; 14(1):8. PubMed ID: 33407740
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
