BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

24 related articles for article (PubMed ID: 24080460)

  • 1. Novel selective, potent naphthyl TRPM8 antagonists identified through a combined ligand- and structure-based virtual screening approach.
    Beccari AR; Gemei M; Lo Monte M; Menegatti N; Fanton M; Pedretti A; Bovolenta S; Nucci C; Molteni A; Rossignoli A; Brandolini L; Taddei A; Za L; Liberati C; Vistoli G
    Sci Rep; 2017 Sep; 7(1):10999. PubMed ID: 28887460
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a Selective TRPM8 Antagonist with Clinical Efficacy in Cold-Related Pain.
    Andrews MD; Af Forselles K; Beaumont K; Galan SR; Glossop PA; Grenie M; Jessiman A; Kenyon AS; Lunn G; Maw G; Owen RM; Pryde DC; Roberts D; Tran TD
    ACS Med Chem Lett; 2015 Apr; 6(4):419-24. PubMed ID: 25893043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
    Matthews JM; Qin N; Colburn RW; Dax SL; Hawkins M; McNally JJ; Reany L; Youngman MA; Baker J; Hutchinson T; Liu Y; Lubin ML; Neeper M; Brandt MR; Stone DJ; Flores CM
    Bioorg Med Chem Lett; 2012 Apr; 22(8):2922-6. PubMed ID: 22421018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.
    Zhu B; Xia M; Xu X; Ludovici DW; Tennakoon M; Youngman MA; Matthews JM; Dax SL; Colburn RW; Qin N; Hutchinson TL; Lubin ML; Brandt MR; Stone DJ; Flores CM; Macielag MJ
    Bioorg Med Chem Lett; 2013 Apr; 23(7):2234-7. PubMed ID: 23411075
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
    Parks DJ; Parsons WH; Colburn RW; Meegalla SK; Ballentine SK; Illig CR; Qin N; Liu Y; Hutchinson TL; Lubin ML; Stone DJ; Baker JF; Schneider CR; Ma J; Damiano BP; Flores CM; Player MR
    J Med Chem; 2011 Jan; 54(1):233-47. PubMed ID: 21128593
    [TBL] [Abstract][Full Text] [Related]  

  • 6. (-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels.
    Ortar G; De Petrocellis L; Morera L; Moriello AS; Orlando P; Morera E; Nalli M; Di Marzo V
    Bioorg Med Chem Lett; 2010 May; 20(9):2729-32. PubMed ID: 20378345
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 5-benzyloxytryptamine as an antagonist of TRPM8.
    DeFalco J; Steiger D; Dourado M; Emerling D; Duncton MA
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7076-9. PubMed ID: 20965726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Serendipity in drug-discovery: a new series of 2-(benzyloxy)benzamides as TRPM8 antagonists.
    Brown A; Ellis D; Favor DA; Kirkup T; Klute W; MacKenny M; McMurray G; Stennett A
    Bioorg Med Chem Lett; 2013 Nov; 23(22):6118-22. PubMed ID: 24080460
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology.
    Journigan VB; Zaveri NT
    Life Sci; 2013 Mar; 92(8-9):425-37. PubMed ID: 23159643
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent progress in fragment-based lead discovery.
    Schulz MN; Hubbard RE
    Curr Opin Pharmacol; 2009 Oct; 9(5):615-21. PubMed ID: 19477685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein structure similarity clustering and natural product structure as guiding principles in drug discovery.
    Koch MA; Waldmann H
    Drug Discov Today; 2005 Apr; 10(7):471-83. PubMed ID: 15809193
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lipophilic Efficiency as an Important Metric in Drug Design.
    Johnson TW; Gallego RA; Edwards MP
    J Med Chem; 2018 Aug; 61(15):6401-6420. PubMed ID: 29589935
    [TBL] [Abstract][Full Text] [Related]  

  • 13.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 14.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 15.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 16.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 17.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 2.