BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

605 related articles for article (PubMed ID: 24086148)

  • 1. Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage.
    Kennedy SR; Salk JJ; Schmitt MW; Loeb LA
    PLoS Genet; 2013; 9(9):e1003794. PubMed ID: 24086148
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA.
    Sanchez-Contreras M; Sweetwyne MT; Kohrn BF; Tsantilas KA; Hipp MJ; Schmidt EK; Fredrickson J; Whitson JA; Campbell MD; Rabinovitch PS; Marcinek DJ; Kennedy SR
    Nucleic Acids Res; 2021 Nov; 49(19):11103-11118. PubMed ID: 34614167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The multi-tissue landscape of somatic mtDNA mutations indicates tissue-specific accumulation and removal in aging.
    Sanchez-Contreras M; Sweetwyne MT; Tsantilas KA; Whitson JA; Campbell MD; Kohrn BF; Kim HJ; Hipp MJ; Fredrickson J; Nguyen MM; Hurley JB; Marcinek DJ; Rabinovitch PS; Kennedy SR
    Elife; 2023 Feb; 12():. PubMed ID: 36799304
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection.
    Ziada AS; Lu MY; Ignas-Menzies J; Paintsil E; Li M; Ogbuagu O; Saberi S; Hsieh AYY; Sattha B; Harrigan PR; Kalloger S; Côté HCF;
    Aging Cell; 2019 Dec; 18(6):e13018. PubMed ID: 31407474
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oxidative stress is not a major contributor to somatic mitochondrial DNA mutations.
    Itsara LS; Kennedy SR; Fox EJ; Yu S; Hewitt JJ; Sanchez-Contreras M; Cardozo-Pelaez F; Pallanck LJ
    PLoS Genet; 2014 Feb; 10(2):e1003974. PubMed ID: 24516391
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mtDNA mutation spectrum in the PolG mutator mouse reveals germline and somatic selection.
    Maclaine KD; Stebbings KA; Llano DA; Havird JC
    BMC Genom Data; 2021 Nov; 22(1):52. PubMed ID: 34823474
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Origins of mtDNA mutations in ageing.
    Szczepanowska K; Trifunovic A
    Essays Biochem; 2017 Jul; 61(3):325-337. PubMed ID: 28698307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial DNA mutations and oxidative damage in aging and diseases: an emerging paradigm of gerontology and medicine.
    Wei YH
    Proc Natl Sci Counc Repub China B; 1998 Apr; 22(2):55-67. PubMed ID: 9615468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Respiratory function decline and DNA mutation in mitochondria, oxidative stress and altered gene expression during aging.
    Wei YH; Wu SB; Ma YS; Lee HC
    Chang Gung Med J; 2009; 32(2):113-32. PubMed ID: 19403001
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Part II. Mitochondrial mutational status of high nitric oxide adapted cell line BT-20 (BT-20-HNO) as it relates to human primary breast tumors.
    De Vitto H; Mendonça BS; Elseth KM; Vesper BJ; Portari EA; Gallo CV; Paradise WA; Rumjanek FD; Radosevich JA
    Tumour Biol; 2013 Feb; 34(1):337-47. PubMed ID: 23238816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases.
    DeBalsi KL; Hoff KE; Copeland WC
    Ageing Res Rev; 2017 Jan; 33():89-104. PubMed ID: 27143693
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxidative damage and mutation to mitochondrial DNA and age-dependent decline of mitochondrial respiratory function.
    Wei YH; Lu CY; Lee HC; Pang CY; Ma YS
    Ann N Y Acad Sci; 1998 Nov; 854():155-70. PubMed ID: 9928427
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.
    Trifunovic A; Hansson A; Wredenberg A; Rovio AT; Dufour E; Khvorostov I; Spelbrink JN; Wibom R; Jacobs HT; Larsson NG
    Proc Natl Acad Sci U S A; 2005 Dec; 102(50):17993-8. PubMed ID: 16332961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidative stress and mitochondrial DNA mutations in human aging.
    Wei YH
    Proc Soc Exp Biol Med; 1998 Jan; 217(1):53-63. PubMed ID: 9421207
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitochondrial and Nuclear DNA Oxidative Damage in Physiological and Pathological Aging.
    Kowalska M; Piekut T; Prendecki M; Sodel A; Kozubski W; Dorszewska J
    DNA Cell Biol; 2020 Aug; 39(8):1410-1420. PubMed ID: 32315547
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial DNA oxidative damage and mutagenesis in Saccharomyces cerevisiae.
    Griffiths LM; Doudican NA; Shadel GS; Doetsch PW
    Methods Mol Biol; 2009; 554():267-86. PubMed ID: 19513680
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial mutations in Caenorhabditis elegans show signatures of oxidative damage and an AT-bias.
    Waneka G; Svendsen JM; Havird JC; Sloan DB
    Genetics; 2021 Oct; 219(2):. PubMed ID: 34849888
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region.
    Pastukh VM; Gorodnya OM; Gillespie MN; Ruchko MV
    Free Radic Biol Med; 2016 Jul; 96():78-88. PubMed ID: 27091693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondrial function and mitochondrial DNA maintenance with advancing age.
    Gaziev AI; Abdullaev S; Podlutsky A
    Biogerontology; 2014; 15(5):417-38. PubMed ID: 25015781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Age-related accumulation of de novo mitochondrial mutations in mammalian oocytes and somatic tissues.
    Arbeithuber B; Hester J; Cremona MA; Stoler N; Zaidi A; Higgins B; Anthony K; Chiaromonte F; Diaz FJ; Makova KD
    PLoS Biol; 2020 Jul; 18(7):e3000745. PubMed ID: 32667908
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.