BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 24086739)

  • 1. A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function.
    Iyer A; Lapointe NE; Zielke K; Berdynski M; Guzman E; Barczak A; Chodakowska-Żebrowska M; Barcikowska M; Feinstein S; Zekanowski C
    PLoS One; 2013; 8(9):e76409. PubMed ID: 24086739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations.
    Xia Y; Sorrentino ZA; Kim JD; Strang KH; Riffe CJ; Giasson BI
    J Biol Chem; 2019 Nov; 294(48):18488-18503. PubMed ID: 31653695
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G.
    Tacik P; DeTure MA; Carlomagno Y; Lin WL; Murray ME; Baker MC; Josephs KA; Boeve BF; Wszolek ZK; Graff-Radford NR; Parisi JE; Petrucelli L; Rademakers R; Isaacson RS; Heilman KM; Petersen RC; Dickson DW; Kouri N
    Brain Pathol; 2017 Sep; 27(5):612-626. PubMed ID: 27529406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tau PET Imaging with [18F]PM-PBB3 in Frontotemporal Dementia with MAPT Mutation.
    Su Y; Fu J; Yu J; Zhao Q; Guan Y; Zuo C; Li M; Tan H; Cheng X
    J Alzheimers Dis; 2020; 76(1):149-157. PubMed ID: 32444551
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathogenic MAPT mutations Q336H and Q336R have isoform-dependent differences in aggregation propensity and microtubule dysfunction.
    Xia Y; Nasif L; Giasson BI
    J Neurochem; 2021 Jul; 158(2):455-466. PubMed ID: 33772783
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Closing the tau loop: the missing tau mutation.
    McCarthy A; Lonergan R; Olszewska DA; O'Dowd S; Cummins G; Magennis B; Fallon EM; Pender N; Huey ED; Cosentino S; O'Rourke K; Kelly BD; O'Connell M; Delon I; Farrell M; Spillantini MG; Rowland LP; Fahn S; Craig P; Hutton M; Lynch T
    Brain; 2015 Oct; 138(Pt 10):3100-9. PubMed ID: 26297556
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [The genetics of dementias. Part 1: Molecular basis of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)].
    Kowalska A
    Postepy Hig Med Dosw (Online); 2009 Jun; 63():278-86. PubMed ID: 19535823
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pick's disease is associated with mutations in the tau gene.
    Pickering-Brown S; Baker M; Yen SH; Liu WK; Hasegawa M; Cairns N; Lantos PL; Rossor M; Iwatsubo T; Davies Y; Allsop D; Furlong R; Owen F; Hardy J; Mann D; Hutton M
    Ann Neurol; 2000 Dec; 48(6):859-67. PubMed ID: 11117542
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
    Wren MC; Zhao J; Liu CC; Murray ME; Atagi Y; Davis MD; Fu Y; Okano HJ; Ogaki K; Strongosky AJ; Tacik P; Rademakers R; Ross OA; Dickson DW; Wszolek ZK; Kanekiyo T; Bu G
    Mol Neurodegener; 2015 Sep; 10():46. PubMed ID: 26373282
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel G335V mutation in the tau gene associated with early onset familial frontotemporal dementia.
    Neumann M; Diekmann S; Bertsch U; Vanmassenhove B; Bogerts B; Kretzschmar HA
    Neurogenetics; 2005 May; 6(2):91-5. PubMed ID: 15765246
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia.
    Paonessa F; Evans LD; Solanki R; Larrieu D; Wray S; Hardy J; Jackson SP; Livesey FJ
    Cell Rep; 2019 Jan; 26(3):582-593.e5. PubMed ID: 30650353
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) due to microtubule-associated protein tau (MAPT) p.P301L mutation, including a patient with globular glial tauopathy.
    Tacik P; Sanchez-Contreras M; DeTure M; Murray ME; Rademakers R; Ross OA; Wszolek ZK; Parisi JE; Knopman DS; Petersen RC; Dickson DW
    Neuropathol Appl Neurobiol; 2017 Apr; 43(3):200-214. PubMed ID: 27859539
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Two pathologically confirmed cases of novel mutations in the MAPT gene causing frontotemporal dementia.
    Shafei R; Woollacott IOC; Mummery CJ; Bocchetta M; Guerreiro R; Bras J; Warren JD; Lashley T; Jaunmuktane Z; Rohrer JD
    Neurobiol Aging; 2020 Mar; 87():141.e15-141.e20. PubMed ID: 31870644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pick's disease associated with the novel Tau gene mutation K369I.
    Neumann M; Schulz-Schaeffer W; Crowther RA; Smith MJ; Spillantini MG; Goedert M; Kretzschmar HA
    Ann Neurol; 2001 Oct; 50(4):503-13. PubMed ID: 11601501
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies.
    Karch CM; Jeng AT; Goate AM
    J Biol Chem; 2012 Dec; 287(51):42751-62. PubMed ID: 23105105
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tau gene mutation K257T causes a tauopathy similar to Pick's disease.
    Rizzini C; Goedert M; Hodges JR; Smith MJ; Jakes R; Hills R; Xuereb JH; Crowther RA; Spillantini MG
    J Neuropathol Exp Neurol; 2000 Nov; 59(11):990-1001. PubMed ID: 11089577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells.
    Lines G; Casey JM; Preza E; Wray S
    Mol Cell Neurosci; 2020 Dec; 109():103553. PubMed ID: 32956830
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pathogenic R5L mutation disrupts formation of Tau complexes on the microtubule by altering local N-terminal structure.
    Cario A; Savastano A; Wood NB; Liu Z; Previs MJ; Hendricks AG; Zweckstetter M; Berger CL
    Proc Natl Acad Sci U S A; 2022 Feb; 119(7):. PubMed ID: 35135879
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tau mutant A152T, a risk factor for FTD/PSP, induces neuronal dysfunction and reduced lifespan independently of aggregation in a C. elegans Tauopathy model.
    Pir GJ; Choudhary B; Mandelkow E; Mandelkow EM
    Mol Neurodegener; 2016 Apr; 11():33. PubMed ID: 27118310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Familial early onset frontotemporal dementia caused by a novel S356T MAPT mutation, initially diagnosed as schizophrenia.
    Momeni P; Wickremaratchi MM; Bell J; Arnold R; Beer R; Hardy J; Revesz T; Neal JW; Morris HR
    Clin Neurol Neurosurg; 2010 Dec; 112(10):917-20. PubMed ID: 20708332
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.