BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 24089445)

  • 1. The cell-cycle regulator CDK4: an emerging therapeutic target in melanoma.
    Sheppard KE; McArthur GA
    Clin Cancer Res; 2013 Oct; 19(19):5320-8. PubMed ID: 24089445
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PRMT5 and CDK4/6 inhibition result in distinctive patterns of alternative splicing in melanoma.
    Chan LH; Wang P; Abuhammad S; Lim LRJ; Cursons J; Sheppard KE; Goode DL
    PLoS One; 2023; 18(11):e0292278. PubMed ID: 37917641
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular pathways: CDK4 inhibitors for cancer therapy.
    Dickson MA
    Clin Cancer Res; 2014 Jul; 20(13):3379-83. PubMed ID: 24795392
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell cycle control as a promising target in melanoma.
    Lee B; Sandhu S; McArthur G
    Curr Opin Oncol; 2015 Mar; 27(2):141-50. PubMed ID: 25588041
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Role of CDK4/6 Inhibition in Breast Cancer.
    Murphy CG; Dickler MN
    Oncologist; 2015 May; 20(5):483-90. PubMed ID: 25876993
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK4/6 inhibitors in breast cancer.
    Dukelow T; Kishan D; Khasraw M; Murphy CG
    Anticancer Drugs; 2015 Sep; 26(8):797-806. PubMed ID: 26053278
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cell Death Signaling.
    Green DR; Llambi F
    Cold Spring Harb Perspect Biol; 2015 Dec; 7(12):. PubMed ID: 26626938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular crosstalk between apoptosis, necroptosis, and survival signaling.
    Vanden Berghe T; Kaiser WJ; Bertrand MJ; Vandenabeele P
    Mol Cell Oncol; 2015; 2(4):e975093. PubMed ID: 27308513
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The CDK4/6 inhibitor LY2835219 overcomes vemurafenib resistance resulting from MAPK reactivation and cyclin D1 upregulation.
    Yadav V; Burke TF; Huber L; Van Horn RD; Zhang Y; Buchanan SG; Chan EM; Starling JJ; Beckmann RP; Peng SB
    Mol Cancer Ther; 2014 Oct; 13(10):2253-63. PubMed ID: 25122067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines.
    Young RJ; Waldeck K; Martin C; Foo JH; Cameron DP; Kirby L; Do H; Mitchell C; Cullinane C; Liu W; Fox SB; Dutton-Regester K; Hayward NK; Jene N; Dobrovic A; Pearson RB; Christensen JG; Randolph S; McArthur GA; Sheppard KE
    Pigment Cell Melanoma Res; 2014 Jul; 27(4):590-600. PubMed ID: 24495407
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting CDK4/6 in patients with cancer.
    Hamilton E; Infante JR
    Cancer Treat Rev; 2016 Apr; 45():129-38. PubMed ID: 27017286
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin-dependent kinases as therapeutic targets in melanoma.
    Miller DM; Flaherty KT
    Pigment Cell Melanoma Res; 2014 May; 27(3):351-65. PubMed ID: 24405945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Semi-mechanistic pharmacokinetic/pharmacodynamic modeling of the antitumor activity of LY2835219, a new cyclin-dependent kinase 4/6 inhibitor, in mice bearing human tumor xenografts.
    Tate SC; Cai S; Ajamie RT; Burke T; Beckmann RP; Chan EM; De Dios A; Wishart GN; Gelbert LM; Cronier DM
    Clin Cancer Res; 2014 Jul; 20(14):3763-74. PubMed ID: 24850847
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study.
    Finn RS; Crown JP; Lang I; Boer K; Bondarenko IM; Kulyk SO; Ettl J; Patel R; Pinter T; Schmidt M; Shparyk Y; Thummala AR; Voytko NL; Fowst C; Huang X; Kim ST; Randolph S; Slamon DJ
    Lancet Oncol; 2015 Jan; 16(1):25-35. PubMed ID: 25524798
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Palbociclib (PD 0332991) : targeting the cell cycle machinery in breast cancer.
    Rocca A; Farolfi A; Bravaccini S; Schirone A; Amadori D
    Expert Opin Pharmacother; 2014 Feb; 15(3):407-20. PubMed ID: 24369047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclin-dependent kinase 4/6 inhibitors in breast cancer therapy.
    Migliaccio I; Di Leo A; Malorni L
    Curr Opin Oncol; 2014 Nov; 26(6):568-75. PubMed ID: 25188473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation.
    Connell-Crowley L; Harper JW; Goodrich DW
    Mol Biol Cell; 1997 Feb; 8(2):287-301. PubMed ID: 9190208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Improved overall survival in melanoma with combined dabrafenib and trametinib.
    Robert C; Karaszewska B; Schachter J; Rutkowski P; Mackiewicz A; Stroiakovski D; Lichinitser M; Dummer R; Grange F; Mortier L; Chiarion-Sileni V; Drucis K; Krajsova I; Hauschild A; Lorigan P; Wolter P; Long GV; Flaherty K; Nathan P; Ribas A; Martin AM; Sun P; Crist W; Legos J; Rubin SD; Little SM; Schadendorf D
    N Engl J Med; 2015 Jan; 372(1):30-9. PubMed ID: 25399551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of Therapeutic Senescence in Vemurafenib-Resistant Melanoma by Extended Inhibition of CDK4/6.
    Yoshida A; Lee EK; Diehl JA
    Cancer Res; 2016 May; 76(10):2990-3002. PubMed ID: 26988987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment.
    VanArsdale T; Boshoff C; Arndt KT; Abraham RT
    Clin Cancer Res; 2015 Jul; 21(13):2905-10. PubMed ID: 25941111
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.