BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

64 related articles for article (PubMed ID: 24090914)

  • 1. Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.
    Abdel-Aziz M; Park SE; Abuo-Rahma Gel-D; Sayed MA; Kwon Y
    Eur J Med Chem; 2013 Nov; 69():427-38. PubMed ID: 24090914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and biological evaluation of novel benzo[6,7]indolo[3,4-c]isoquinolines as anticancer agents with topoisomerase I inhibition.
    Sakai K; Soshima T; Hirose Y; Ishibashi F; Hirao S
    Bioorg Med Chem Lett; 2024 May; 104():129710. PubMed ID: 38518997
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.
    Elsayed MSA; Su Y; Wang P; Sethi T; Agama K; Ravji A; Redon CE; Kiselev E; Horzmann KA; Freeman JL; Pommier Y; Cushman M
    J Med Chem; 2017 Jul; 60(13):5364-5376. PubMed ID: 28657311
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Thiopyrimidine/chalcone hybrids: design, synthesis, ADMET prediction, and anticancer evaluation as STAT3/STAT5a inhibitors.
    Lamie PF; Philoppes JN
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):864-879. PubMed ID: 32208772
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn-BNP)-Coupled Metagenomics.
    Wang Z; Kasper A; Takahashi M; Morales Amador A; Bhattacharjee A; Kan J; Hernandez Y; Ternei M; Brady SF
    Angew Chem Int Ed Engl; 2024 Apr; 63(17):e202317187. PubMed ID: 38231130
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ciprofloxacin is a potential topoisomerase II inhibitor for the treatment of NSCLC.
    Kloskowski T; Gurtowska N; Olkowska J; Nowak JM; Adamowicz J; Tworkiewicz J; Dębski R; Grzanka A; Drewa T
    Int J Oncol; 2012 Dec; 41(6):1943-9. PubMed ID: 23042104
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ciprofloxacin and Norfloxacin Hybrid Compounds: Potential Anticancer Agents.
    Peter S; Aderibigbe BA
    Curr Top Med Chem; 2024; 24(7):644-665. PubMed ID: 38357952
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G; Li C; He L; Lei K; Wang F; Pu Y; Yang Z; Cao D; Ma L; Chen J; Sang Y; Liang X; Xiang M; Peng A; Wei Y; Chen L
    Bioorg Med Chem; 2014 Apr; 22(7):2060-79. PubMed ID: 24629450
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Advancements in Synthetic Strategies and Biological Effects of Ciprofloxacin Derivatives: A Review.
    Khwaza V; Mlala S; Aderibigbe BA
    Int J Mol Sci; 2024 Apr; 25(9):. PubMed ID: 38732134
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives.
    Adly ME; Gedawy EM; El-Malah AA; Khalil OM
    Sci Rep; 2024 Mar; 14(1):6175. PubMed ID: 38485748
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protease inhibition, in vitro antibacterial and IFD/MM-GBSA studies of ciprofloxacin-based acetanilides.
    Akhtar R; Zahoor AF; Mansha A; Kamal S; Khan SG; Raza Z; Ali KG
    PLoS One; 2023; 18(3):e0281044. PubMed ID: 37000820
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and molecular docking of new N4-piperazinyl ciprofloxacin hybrids as antimicrobial DNA gyrase inhibitors.
    Mohammed HHH; Ali DME; Badr M; Habib AGK; Mahmoud AM; Farhan SM; Gany SSHAE; Mohamad SA; Hayallah AM; Abbas SH; Abuo-Rahma GEA
    Mol Divers; 2023 Aug; 27(4):1751-1765. PubMed ID: 36152132
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fluoroquinolones Hybrid Molecules as Promising Antibacterial Agents in the Fight against Antibacterial Resistance.
    Lungu IA; Moldovan OL; Biriș V; Rusu A
    Pharmaceutics; 2022 Aug; 14(8):. PubMed ID: 36015376
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization.
    Mohammed HHH; Abd El-Hafeez AA; Ebeid K; Mekkawy AI; Abourehab MAS; Wafa EI; Alhaj-Suliman SO; Salem AK; Ghosh P; Abuo-Rahma GEA; Hayallah AM; Abbas SH
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):1346-1363. PubMed ID: 35548854
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular targets and anticancer activity of quinoline-chalcone hybrids: literature review.
    Mohamed MFA; Abuo-Rahma GEA
    RSC Adv; 2020 Aug; 10(52):31139-31155. PubMed ID: 35520674
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluoroquinolones' Biological Activities against Laboratory Microbes and Cancer Cell Lines.
    Suaifan GARY; Mohammed AAM; Alkhawaja BA
    Molecules; 2022 Mar; 27(5):. PubMed ID: 35268759
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-Proliferative and Pro-Apoptotic Activities of Synthesized 3,4,5 Tri-Methoxy Ciprofloxacin Chalcone Hybrid, through p53 Up-Regulation in HepG2 and MCF7 Cell Lines.
    Eisa MA; Fathy M; Abuo-Rahma GEAA; Abdel-Aziz M; Nazmy MH
    Asian Pac J Cancer Prev; 2021 Oct; 22(10):3393-3404. PubMed ID: 34711017
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Current progress of fluoroquinolones-increased risk of aortic aneurysm and dissection.
    Jun C; Fang B
    BMC Cardiovasc Disord; 2021 Sep; 21(1):470. PubMed ID: 34583637
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, antitumor, antibacterial and urease inhibitory evaluation of new piperazinyl N-4 carbamoyl functionalized ciprofloxacin derivatives.
    Abdel-Aal MAA; Shaykoon MSA; Abuo-Rahma GEAA; Mohamed MFA; Badr M; Abdel-Aziz SA
    Pharmacol Rep; 2021 Jun; 73(3):891-906. PubMed ID: 33389728
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 4.