272 related articles for article (PubMed ID: 24092756)
1. Molecular basis of cannabinoid CB1 receptor coupling to the G protein heterotrimer Gαiβγ: identification of key CB1 contacts with the C-terminal helix α5 of Gαi.
Shim JY; Ahn KH; Kendall DA
J Biol Chem; 2013 Nov; 288(45):32449-32465. PubMed ID: 24092756
[TBL] [Abstract][Full Text] [Related]
2. The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer.
Liu P; Jia MZ; Zhou XE; De Waal PW; Dickson BM; Liu B; Hou L; Yin YT; Kang YY; Shi Y; Melcher K; Xu HE; Jiang Y
Acta Pharmacol Sin; 2016 Sep; 37(9):1259-72. PubMed ID: 27498775
[TBL] [Abstract][Full Text] [Related]
3. Pivotal role of extended linker 2 in the activation of Gα by G protein-coupled receptor.
Huang J; Sun Y; Zhang JJ; Huang XY
J Biol Chem; 2015 Jan; 290(1):272-83. PubMed ID: 25414258
[TBL] [Abstract][Full Text] [Related]
4. Structural basis of G protein-coupled receptor-Gi protein interaction: formation of the cannabinoid CB2 receptor-Gi protein complex.
Mnpotra JS; Qiao Z; Cai J; Lynch DL; Grossfield A; Leioatts N; Hurst DP; Pitman MC; Song ZH; Reggio PH
J Biol Chem; 2014 Jul; 289(29):20259-72. PubMed ID: 24855641
[TBL] [Abstract][Full Text] [Related]
5. Heterotrimeric G-protein alpha-subunit adopts a "preactivated" conformation when associated with betagamma-subunits.
Abdulaev NG; Ngo T; Zhang C; Dinh A; Brabazon DM; Ridge KD; Marino JP
J Biol Chem; 2005 Nov; 280(45):38071-80. PubMed ID: 16129667
[TBL] [Abstract][Full Text] [Related]
6. Signaling by a non-dissociated complex of G protein βγ and α subunits stimulated by a receptor-independent activator of G protein signaling, AGS8.
Yuan C; Sato M; Lanier SM; Smrcka AV
J Biol Chem; 2007 Jul; 282(27):19938-47. PubMed ID: 17446173
[TBL] [Abstract][Full Text] [Related]
7. Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.
Gulati S; Jin H; Masuho I; Orban T; Cai Y; Pardon E; Martemyanov KA; Kiser PD; Stewart PL; Ford CP; Steyaert J; Palczewski K
Nat Commun; 2018 May; 9(1):1996. PubMed ID: 29777099
[TBL] [Abstract][Full Text] [Related]
8. Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complex.
Shim JY; Khurana L; Kendall DA
Proteins; 2016 Apr; 84(4):532-43. PubMed ID: 26994549
[TBL] [Abstract][Full Text] [Related]
9. Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a Gα
Porcu A; Melis M; Turecek R; Ullrich C; Mocci I; Bettler B; Gessa GL; Castelli MP
Neuropharmacology; 2018 May; 133():107-120. PubMed ID: 29407764
[TBL] [Abstract][Full Text] [Related]
10. Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling.
Evanko DS; Thiyagarajan MM; Takida S; Wedegaertner PB
Cell Signal; 2005 Oct; 17(10):1218-28. PubMed ID: 16038796
[TBL] [Abstract][Full Text] [Related]
11. Dissociated GαGTP and Gβγ protein subunits are the major activated form of heterotrimeric Gi/o proteins.
Bondar A; Lazar J
J Biol Chem; 2014 Jan; 289(3):1271-81. PubMed ID: 24307173
[TBL] [Abstract][Full Text] [Related]
12. Structural determinants involved in the formation and activation of G protein betagamma dimers.
McIntire WE
Neurosignals; 2009; 17(1):82-99. PubMed ID: 19212142
[TBL] [Abstract][Full Text] [Related]
13. Bidirectional allosteric interactions between cannabinoid receptor 1 (CB
Bagher AM; Laprairie RB; Toguri JT; Kelly MEM; Denovan-Wright EM
Eur J Pharmacol; 2017 Oct; 813():66-83. PubMed ID: 28734930
[TBL] [Abstract][Full Text] [Related]
14. Large-scale conformational rearrangement of the α5-helix of Gα subunits in complex with the guanine nucleotide exchange factor Ric8A.
Srivastava D; Artemyev NO
J Biol Chem; 2019 Nov; 294(47):17875-17882. PubMed ID: 31624147
[TBL] [Abstract][Full Text] [Related]
15. A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit.
Kaya AI; Lokits AD; Gilbert JA; Iverson TM; Meiler J; Hamm HE
J Biol Chem; 2014 Aug; 289(35):24475-87. PubMed ID: 25037222
[TBL] [Abstract][Full Text] [Related]
16. Transmembrane helical domain of the cannabinoid CB1 receptor.
Shim JY
Biophys J; 2009 Apr; 96(8):3251-62. PubMed ID: 19383469
[TBL] [Abstract][Full Text] [Related]
17. Structural and molecular characterization of a preferred protein interaction surface on G protein beta gamma subunits.
Davis TL; Bonacci TM; Sprang SR; Smrcka AV
Biochemistry; 2005 Aug; 44(31):10593-604. PubMed ID: 16060668
[TBL] [Abstract][Full Text] [Related]
18. Isolation and structure-function characterization of a signaling-active rhodopsin-G protein complex.
Gao Y; Westfield G; Erickson JW; Cerione RA; Skiniotis G; Ramachandran S
J Biol Chem; 2017 Aug; 292(34):14280-14289. PubMed ID: 28655769
[TBL] [Abstract][Full Text] [Related]
19. Allosteric modulator ORG27569 induces CB1 cannabinoid receptor high affinity agonist binding state, receptor internalization, and Gi protein-independent ERK1/2 kinase activation.
Ahn KH; Mahmoud MM; Kendall DA
J Biol Chem; 2012 Apr; 287(15):12070-82. PubMed ID: 22343625
[TBL] [Abstract][Full Text] [Related]
20. Computationally-predicted CB1 cannabinoid receptor mutants show distinct patterns of salt-bridges that correlate with their level of constitutive activity reflected in G protein coupling levels, thermal stability, and ligand binding.
Ahn KH; Scott CE; Abrol R; Goddard WA; Kendall DA
Proteins; 2013 Aug; 81(8):1304-17. PubMed ID: 23408552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]