BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

756 related articles for article (PubMed ID: 24095279)

  • 21. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway.
    Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM
    Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1.
    Schweitzer LD; Comb WC; Bar-Peled L; Sabatini DM
    Cell Rep; 2015 Sep; 12(9):1445-55. PubMed ID: 26299971
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex.
    Cui Z; Napolitano G; de Araujo MEG; Esposito A; Monfregola J; Huber LA; Ballabio A; Hurley JH
    Nature; 2023 Feb; 614(7948):572-579. PubMed ID: 36697823
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
    Efeyan A; Zoncu R; Chang S; Gumper I; Snitkin H; Wolfson RL; Kirak O; Sabatini DD; Sabatini DM
    Nature; 2013 Jan; 493(7434):679-83. PubMed ID: 23263183
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Signalling: Finding the GAPs in mTORC1 signalling.
    Lokody I
    Nat Rev Cancer; 2013 Dec; 13(12):824. PubMed ID: 24226192
    [No Abstract]   [Full Text] [Related]  

  • 26. Regulation of mTORC1 by amino acids.
    Bar-Peled L; Sabatini DM
    Trends Cell Biol; 2014 Jul; 24(7):400-6. PubMed ID: 24698685
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Redundant electrostatic interactions between GATOR1 and the Rag GTPase heterodimer drive efficient amino acid sensing in human cells.
    Doxsey DD; Tettoni SD; Egri SB; Shen K
    J Biol Chem; 2023 Jul; 299(7):104880. PubMed ID: 37269949
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.
    Ögmundsdóttir MH; Heublein S; Kazi S; Reynolds B; Visvalingam SM; Shaw MK; Goberdhan DC
    PLoS One; 2012; 7(5):e36616. PubMed ID: 22574197
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Folliculin promotes substrate-selective mTORC1 activity by activating RagC to recruit TFE3.
    Li K; Wada S; Gosis BS; Thorsheim C; Loose P; Arany Z
    PLoS Biol; 2022 Mar; 20(3):e3001594. PubMed ID: 35358174
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Amino Acids Stimulate TORC1 through Lst4-Lst7, a GTPase-Activating Protein Complex for the Rag Family GTPase Gtr2.
    Péli-Gulli MP; Sardu A; Panchaud N; Raucci S; De Virgilio C
    Cell Rep; 2015 Oct; 13(1):1-7. PubMed ID: 26387955
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
    Wang S; Tsun ZY; Wolfson RL; Shen K; Wyant GA; Plovanich ME; Yuan ED; Jones TD; Chantranupong L; Comb W; Wang T; Bar-Peled L; Zoncu R; Straub C; Kim C; Park J; Sabatini BL; Sabatini DM
    Science; 2015 Jan; 347(6218):188-94. PubMed ID: 25567906
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
    Shen K; Valenstein ML; Gu X; Sabatini DM
    J Biol Chem; 2019 Feb; 294(8):2970-2975. PubMed ID: 30651352
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes.
    Martina JA; Puertollano R
    J Cell Biol; 2013 Feb; 200(4):475-91. PubMed ID: 23401004
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet.
    Kimball SR; Ravi S; Gordon BS; Dennis MD; Jefferson LS
    J Nutr; 2015 Nov; 145(11):2496-502. PubMed ID: 26400964
    [TBL] [Abstract][Full Text] [Related]  

  • 36. SZT2 dictates GATOR control of mTORC1 signalling.
    Peng M; Yin N; Li MO
    Nature; 2017 Mar; 543(7645):433-437. PubMed ID: 28199315
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
    Jin G; Lee SW; Zhang X; Cai Z; Gao Y; Chou PC; Rezaeian AH; Han F; Wang CY; Yao JC; Gong Z; Chan CH; Huang CY; Tsai FJ; Tsai CH; Tu SH; Wu CH; Sarbassov dos D; Ho YS; Lin HK
    Mol Cell; 2015 Jun; 58(6):989-1000. PubMed ID: 26051179
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation.
    Suryawan A; Davis TA
    J Nutr; 2018 Jun; 148(6):825-833. PubMed ID: 29796625
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Key mediators of intracellular amino acids signaling to mTORC1 activation.
    Duan Y; Li F; Tan K; Liu H; Li Y; Liu Y; Kong X; Tang Y; Wu G; Yin Y
    Amino Acids; 2015 May; 47(5):857-67. PubMed ID: 25701492
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Rheb and Rags come together at the lysosome to activate mTORC1.
    Groenewoud MJ; Zwartkruis FJ
    Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 38.