BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

70 related articles for article (PubMed ID: 24103879)

  • 1. [Inhibitory effects of gamma secretase inhibitor on human multiple myeloma xenograft mouse model].
    Liu QQ; Liu JL; Guo DM; Teng QL
    Zhonghua Xue Ye Xue Za Zhi; 2013 Sep; 34(9):794-7. PubMed ID: 24103879
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model.
    Groeneweg JW; Hall TR; Zhang L; Kim M; Byron VF; Tambouret R; Sathayanrayanan S; Foster R; Rueda BR; Growdon WB
    Gynecol Oncol; 2014 Jun; 133(3):607-15. PubMed ID: 24667249
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Monoclonal antibody against brain derived neurotrophic factor inhibits myeloma growth and angiogenesis in the xenograft NOD/SCID animal model].
    Wang YD; Hu Y; Zhang L; Huang J; Sun CY
    Zhonghua Xue Ye Xue Za Zhi; 2007 Oct; 28(10):659-63. PubMed ID: 18399169
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MRK003, a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma.
    Ramakrishnan V; Ansell S; Haug J; Grote D; Kimlinger T; Stenson M; Timm M; Wellik L; Halling T; Rajkumar SV; Kumar S
    Leukemia; 2012 Feb; 26(2):340-8. PubMed ID: 21826062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.
    Rao SS; O'Neil J; Liberator CD; Hardwick JS; Dai X; Zhang T; Tyminski E; Yuan J; Kohl NE; Richon VM; Van der Ploeg LH; Carroll PM; Draetta GF; Look AT; Strack PR; Winter CG
    Cancer Res; 2009 Apr; 69(7):3060-8. PubMed ID: 19318552
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
    Efferson CL; Winkelmann CT; Ware C; Sullivan T; Giampaoli S; Tammam J; Patel S; Mesiti G; Reilly JF; Gibson RE; Buser C; Yeatman T; Coppola D; Winter C; Clark EA; Draetta GF; Strack PR; Majumder PK
    Cancer Res; 2010 Mar; 70(6):2476-84. PubMed ID: 20197467
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Notch1 overexpression promotes cell growth and tumor angiogenesis in myeloma.
    Guo D; Li C; Teng Q; Sun Z; Li Y; Zhang C
    Neoplasma; 2013; 60(1):33-40. PubMed ID: 23067214
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the Notch1 and mTOR pathways in a mouse T-ALL model.
    Cullion K; Draheim KM; Hermance N; Tammam J; Sharma VM; Ware C; Nikov G; Krishnamoorthy V; Majumder PK; Kelliher MA
    Blood; 2009 Jun; 113(24):6172-81. PubMed ID: 19246562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Inhibitory effect of phenylhexyl isothiocyanate on notch signaling of multiple myeloma cells in vitro].
    Hong XL; Zhang ZC; Zhao JN; Lu QY
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2011 Aug; 19(4):940-3. PubMed ID: 21867619
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Inhibitory effect of pumpkin protein on expression of Notch signal in RPMI8226 myeloma cells].
    Liu TB; Yang P; Xie JM; Hu JD
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2014 Aug; 22(4):1012-5. PubMed ID: 25130819
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antitumor effect of anti-brain derived neurotrophic factor monoclonal antibody in human multiple myeloma xenograft animal model.
    Wang YD; Hu Y; Huang J; Zhang L; Sun CY
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2008 Oct; 16(5):1069-72. PubMed ID: 18928597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MK2206 enhances the cytocidal effects of bufalin in multiple myeloma by inhibiting the AKT/mTOR pathway.
    Xiang RF; Wang Y; Zhang N; Xu WB; Cao Y; Tong J; Li JM; Wu YL; Yan H
    Cell Death Dis; 2017 May; 8(5):e2776. PubMed ID: 28492559
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Notch1 Gene Silenced by RNAi Inhibits Oncogenicity of Myeloma Cell Line].
    Li ML; Chen MQ; Zhang P; Lu QY
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2017 Dec; 25(6):1685-1689. PubMed ID: 29262898
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma.
    Chang HH; Lee H; Hu MK; Tsao PN; Juan HF; Huang MC; Shih YY; Wang BJ; Jeng YM; Chang CL; Huang SF; Tsay YG; Hsieh FJ; Lin KH; Hsu WM; Liao YF
    Clin Cancer Res; 2010 Sep; 16(17):4411-20. PubMed ID: 20736329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preclinical activity of a novel multiple tyrosine kinase and aurora kinase inhibitor, ENMD-2076, against multiple myeloma.
    Wang X; Sinn AL; Pollok K; Sandusky G; Zhang S; Chen L; Liang J; Crean CD; Suvannasankha A; Abonour R; Sidor C; Bray MR; Farag SS
    Br J Haematol; 2010 Aug; 150(3):313-25. PubMed ID: 20560971
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
    Tammam J; Ware C; Efferson C; O'Neil J; Rao S; Qu X; Gorenstein J; Angagaw M; Kim H; Kenific C; Kunii K; Leach KJ; Nikov G; Zhao J; Dai X; Hardwick J; Scott M; Winter C; Bristow L; Elbi C; Reilly JF; Look T; Draetta G; Van der Ploeg L; Kohl NE; Strack PR; Majumder PK
    Br J Pharmacol; 2009 Nov; 158(5):1183-95. PubMed ID: 19775282
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Inhibition of hypoxia-inducible factor-1 alpha in RPMI8226 myeloma cells results in reduced tumor growth in nude mice].
    Li BZ; Zhuang WZ; Chen P; Fu JX
    Zhonghua Xue Ye Xue Za Zhi; 2008 Apr; 29(4):247-51. PubMed ID: 18843979
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch signaling promotes growth and invasion in uveal melanoma.
    Asnaghi L; Ebrahimi KB; Schreck KC; Bar EE; Coonfield ML; Bell WR; Handa J; Merbs SL; Harbour JW; Eberhart CG
    Clin Cancer Res; 2012 Feb; 18(3):654-65. PubMed ID: 22228632
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Strong therapeutic potential of γ-secretase inhibitor MRK003 for CD44-high and CD133-low glioblastoma initiating cells.
    Tanaka S; Nakada M; Yamada D; Nakano I; Todo T; Ino Y; Hoshii T; Tadokoro Y; Ohta K; Ali MA; Hayashi Y; Hamada J; Hirao A
    J Neurooncol; 2015 Jan; 121(2):239-50. PubMed ID: 25293440
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockade.
    Chu Q; Orr BA; Semenkow S; Bar EE; Eberhart CG
    Clin Cancer Res; 2013 Jun; 19(12):3224-33. PubMed ID: 23630166
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.