147 related articles for article (PubMed ID: 24105984)
1. The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux.
Nomura S; Umeda T; Tomiyama T; Mori H
J Neurosci Res; 2013 Dec; 91(12):1541-50. PubMed ID: 24105984
[TBL] [Abstract][Full Text] [Related]
2. Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.
Umeda T; Tomiyama T; Sakama N; Tanaka S; Lambert MP; Klein WL; Mori H
J Neurosci Res; 2011 Jul; 89(7):1031-42. PubMed ID: 21488093
[TBL] [Abstract][Full Text] [Related]
3. Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.
Yang GZ; Yang M; Lim Y; Lu JJ; Wang TH; Qi JG; Zhong JH; Zhou XF
J Neurochem; 2012 Sep; 122(5):1010-22. PubMed ID: 22731248
[TBL] [Abstract][Full Text] [Related]
4. Differential regulation of amyloid precursor protein sorting with pathological mutations results in a distinct effect on amyloid-β production.
Lin YC; Wang JY; Wang KC; Liao JY; Cheng IH
J Neurochem; 2014 Nov; 131(4):407-12. PubMed ID: 25053581
[TBL] [Abstract][Full Text] [Related]
5. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
[TBL] [Abstract][Full Text] [Related]
6. Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking.
Urano Y; Ochiai S; Noguchi N
FASEB J; 2013 Oct; 27(10):4305-15. PubMed ID: 23839932
[TBL] [Abstract][Full Text] [Related]
7. Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice.
Umeda T; Tomiyama T; Kitajima E; Idomoto T; Nomura S; Lambert MP; Klein WL; Mori H
Life Sci; 2012 Dec; 91(23-24):1169-76. PubMed ID: 22273754
[TBL] [Abstract][Full Text] [Related]
8. Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation.
Kulic L; McAfoose J; Welt T; Tackenberg C; Späni C; Wirth F; Finder V; Konietzko U; Giese M; Eckert A; Noriaki K; Shimizu T; Murakami K; Irie K; Rasool S; Glabe C; Hock C; Nitsch RM
Transl Psychiatry; 2012 Nov; 2(11):e183. PubMed ID: 23149447
[TBL] [Abstract][Full Text] [Related]
9. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.
Maulik M; Peake K; Chung J; Wang Y; Vance JE; Kar S
Hum Mol Genet; 2015 Dec; 24(24):7132-50. PubMed ID: 26433932
[TBL] [Abstract][Full Text] [Related]
10. Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.
Umeda T; Ramser EM; Yamashita M; Nakajima K; Mori H; Silverman MA; Tomiyama T
Acta Neuropathol Commun; 2015 Aug; 3():51. PubMed ID: 26293809
[TBL] [Abstract][Full Text] [Related]
11. The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells.
Nishitsuji K; Tomiyama T; Ishibashi K; Ito K; Teraoka R; Lambert MP; Klein WL; Mori H
Am J Pathol; 2009 Mar; 174(3):957-69. PubMed ID: 19164507
[TBL] [Abstract][Full Text] [Related]
12. SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface.
Wang J; Shan C; Cao W; Zhang C; Teng J; Chen J
Hum Mol Genet; 2013 Dec; 22(24):4888-900. PubMed ID: 23863461
[TBL] [Abstract][Full Text] [Related]
13. Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation.
Rönnbäck A; Pavlov PF; Mansory M; Gonze P; Marlière N; Winblad B; Graff C; Behbahani H
J Neurochem; 2016 Feb; 136(3):497-502. PubMed ID: 26500157
[TBL] [Abstract][Full Text] [Related]
14. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.
Esposito L; Gan L; Yu GQ; Essrich C; Mucke L
J Neurochem; 2004 Dec; 91(6):1260-74. PubMed ID: 15584903
[TBL] [Abstract][Full Text] [Related]
15. A nontoxigenic form of Shiga toxin 2 suppresses the production of amyloid β by altering the intracellular transport of amyloid precursor protein through its receptor-binding B-subunit.
Sato W; Watanabe-Takahashi M; Hamabata T; Furukawa K; Funamoto S; Nishikawa K
Biochem Biophys Res Commun; 2021 Jun; 557():247-253. PubMed ID: 33894410
[TBL] [Abstract][Full Text] [Related]
16. Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation.
Liu K; Liu Y; Xu Y; Nandakumar KS; Shen X; Lin J; Li C; He C; Zhou C
J Cell Biochem; 2019 Sep; 120(9):15604-15615. PubMed ID: 31111546
[TBL] [Abstract][Full Text] [Related]
17. Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.
Soejima N; Ohyagi Y; Nakamura N; Himeno E; Iinuma KM; Sakae N; Yamasaki R; Tabira T; Murakami K; Irie K; Kinoshita N; LaFerla FM; Kiyohara Y; Iwaki T; Kira J
Curr Alzheimer Res; 2013 Jan; 10(1):11-20. PubMed ID: 22950910
[TBL] [Abstract][Full Text] [Related]
18. Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production.
Suárez-Calvet M; Belbin O; Pera M; Badiola N; Magrané J; Guardia-Laguarta C; Muñoz L; Colom-Cadena M; Clarimón J; Lleó A
J Neurochem; 2014 Jan; 128(2):330-9. PubMed ID: 24117942
[TBL] [Abstract][Full Text] [Related]
19. Divalent metal transporter 1 is involved in amyloid precursor protein processing and Abeta generation.
Zheng W; Xin N; Chi ZH; Zhao BL; Zhang J; Li JY; Wang ZY
FASEB J; 2009 Dec; 23(12):4207-17. PubMed ID: 19679638
[TBL] [Abstract][Full Text] [Related]
20. Regulation of cholesterol efflux by amyloid beta secretion.
Umeda T; Mori H; Zheng H; Tomiyama T
J Neurosci Res; 2010 Jul; 88(9):1985-94. PubMed ID: 20155813
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
