These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 24106106)

  • 1. Amythiamicin D and related thiopeptides as inhibitors of the bacterial elongation factor EF-Tu: modification of the amino acid at carbon atom C2 of ring C dramatically influences activity.
    Gross S; Nguyen F; Bierschenk M; Sohmen D; Menzel T; Antes I; Wilson DN; Bach T
    ChemMedChem; 2013 Dec; 8(12):1954-62. PubMed ID: 24106106
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes.
    Zuurmond AM; Martien de Graaf J; Olsthoorn-Tieleman LN; van Duyl BY; Mörhle VG; Jurnak F; Mesters JR; Hilgenfeld R; Kraal B
    J Mol Biol; 2000 Dec; 304(5):995-1005. PubMed ID: 11124042
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.
    Morris RP; Leeds JA; Naegeli HU; Oberer L; Memmert K; Weber E; LaMarche MJ; Parker CN; Burrer N; Esterow S; Hein AE; Schmitt EK; Krastel P
    J Am Chem Soc; 2009 Apr; 131(16):5946-55. PubMed ID: 19338336
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensitivity of elongation factor Tu (EF-Tu) from different bacterial species to the antibiotics efrotomycin, pulvomycin and MDL 62879.
    Landini P; Bandera M; Soffientini A; Goldstein BP
    J Gen Microbiol; 1993 Apr; 139(4):769-74. PubMed ID: 8515234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of an EF-Tu complex with a thiazolyl peptide antibiotic determined at 2.35 A resolution: atomic basis for GE2270A inhibition of EF-Tu.
    Heffron SE; Jurnak F
    Biochemistry; 2000 Jan; 39(1):37-45. PubMed ID: 10625477
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of the antibiotic pulvomycin on the elongation factor Tu-dependent reactions. Comparison with other antibiotics.
    Anborgh PH; Okamura S; Parmeggiani A
    Biochemistry; 2004 Dec; 43(49):15550-6. PubMed ID: 15581367
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immobilization of a novel antibacterial agent on solid phase and subsequent isolation of EF-Tu.
    Deibel MR; Bodnar AL; Yem AW; Wolfe CL; Heckaman CL; Bohanon MJ; Mathews WR; Sweeney MT; Zurenko GE; Marotti KR; Boyle TP; Thorarensen A
    Bioconjug Chem; 2004; 15(2):333-43. PubMed ID: 15025529
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of bacterial protein synthesis by elongation-factor-Tu-binding antibiotics MDL 62,879 and efrotomycin.
    Landini P; Bandera M; Goldstein BP; Ripamonti F; Soffientini A; Islam K; Denaro M
    Biochem J; 1992 May; 283 ( Pt 3)(Pt 3):649-52. PubMed ID: 1590753
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antibiotic inhibitors of organellar protein synthesis in Plasmodium falciparum.
    Clough B; Rangachari K; Strath M; Preiser PR; Wilson RJ
    Protist; 1999 Aug; 150(2):189-95. PubMed ID: 10505418
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antibiotics MDL 62,879 and kirromycin bind to distinct and independent sites of elongation factor Tu (EF-Tu).
    Landini P; Soffientini A; Monti F; Lociuro S; Marzorati E; Islam K
    Biochemistry; 1996 Dec; 35(48):15288-94. PubMed ID: 8952479
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
    Parmeggiani A; Krab IM; Okamura S; Nielsen RC; Nyborg J; Nissen P
    Biochemistry; 2006 Jun; 45(22):6846-57. PubMed ID: 16734421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Elongation factor Tu1 of the antibiotic GE2270A producer Planobispora rosea has an unexpected resistance profile against EF-Tu targeted antibiotics.
    Möhrle VG; Tieleman LN; Kraal B
    Biochem Biophys Res Commun; 1997 Jan; 230(2):320-6. PubMed ID: 9016775
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of novel inhibitors of bacterial translation elongation factors.
    Jayasekera MM; Onheiber K; Keith J; Venkatesan H; Santillan A; Stocking EM; Tang L; Miller J; Gomez L; Rhead B; Delcamp T; Huang S; Wolin R; Bobkova EV; Shaw KJ
    Antimicrob Agents Chemother; 2005 Jan; 49(1):131-6. PubMed ID: 15616286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Total syntheses of the thiopeptides amythiamicin C and D.
    Ammer C; Bach T
    Chemistry; 2010 Dec; 16(47):14083-93. PubMed ID: 20960446
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solution structures of thiopeptide antibiotics.
    Lewis RJ; Hughes RA; Alcaraz L; Thompson SP; Moody CJ
    Chem Commun (Camb); 2006 Oct; (40):4215-7. PubMed ID: 17031436
    [TBL] [Abstract][Full Text] [Related]  

  • 16. EF-Tu binding peptides identified, dissected, and affinity optimized by phage display.
    Murase K; Morrison KL; Tam PY; Stafford RL; Jurnak F; Weiss GA
    Chem Biol; 2003 Feb; 10(2):161-8. PubMed ID: 12618188
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of mutagenesis of Gln97 in the switch II region of Escherichia coli elongation factor Tu on its interaction with guanine nucleotides, elongation factor Ts, and aminoacyl-tRNA.
    Navratil T; Spremulli LL
    Biochemistry; 2003 Nov; 42(46):13587-95. PubMed ID: 14622005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antimicrobial activities of chemically modified thiazolyl peptide antibiotic MDL 62,879 (GE2270A).
    Lociuro S; Tavecchia P; Marzorati E; Landini P; Goldstein BP; Denaro M; Ciabatti R
    J Antibiot (Tokyo); 1997 Apr; 50(4):344-9. PubMed ID: 9186562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitory mechanisms of antibiotics targeting elongation factor Tu.
    Hogg T; Mesters JR; Hilgenfeld R
    Curr Protein Pept Sci; 2002 Feb; 3(1):121-31. PubMed ID: 12370016
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The affinity of elongation factor Tu for an aminoacyl-tRNA is modulated by the esterified amino acid.
    Dale T; Sanderson LE; Uhlenbeck OC
    Biochemistry; 2004 May; 43(20):6159-66. PubMed ID: 15147200
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.