BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 24107130)

  • 1. Oxidation of polychlorinated biphenyls by liver tissue slices from phenobarbital-pretreated mice is congener-specific and atropselective.
    Wu X; Duffel M; Lehmler HJ
    Chem Res Toxicol; 2013 Nov; 26(11):1642-51. PubMed ID: 24107130
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) atropisomers in tissue slices from phenobarbital or dexamethasone-induced rats is sex-dependent.
    Wu X; Kania-Korwel I; Chen H; Stamou M; Dammanahalli KJ; Duffel M; Lein PJ; Lehmler HJ
    Xenobiotica; 2013 Nov; 43(11):933-47. PubMed ID: 23581876
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) is enantioselectively oxidized to hydroxylated metabolites by rat liver microsomes.
    Wu X; Pramanik A; Duffel MW; Hrycay EG; Bandiera SM; Lehmler HJ; Kania-Korwel I
    Chem Res Toxicol; 2011 Dec; 24(12):2249-57. PubMed ID: 22026639
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microsomal oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) results in species-dependent chiral signatures of the hydroxylated metabolites.
    Wu X; Kammerer A; Lehmler HJ
    Environ Sci Technol; 2014 Feb; 48(4):2436-44. PubMed ID: 24467194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of thiol antioxidants on the atropselective oxidation of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) by rat liver microsomes.
    Wu X; Lehmler HJ
    Environ Sci Pollut Res Int; 2016 Feb; 23(3):2081-8. PubMed ID: 26155892
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites.
    Uwimana E; Maiers A; Li X; Lehmler HJ
    Environ Sci Technol; 2017 Feb; 51(3):1820-1829. PubMed ID: 28038482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing the Role of CYP2 Enzymes in the Atropselective Metabolism of Polychlorinated Biphenyls Using Liver Microsomes from Transgenic Mouse Models.
    Lehmler HJ; Uwimana E; Dean LE; Kovalchuk N; Zhang QY; Ding X
    Chem Res Toxicol; 2022 Dec; 35(12):2310-2323. PubMed ID: 36473170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human CYP2A6, CYP2B6, AND CYP2E1 Atropselectively Metabolize Polychlorinated Biphenyls to Hydroxylated Metabolites.
    Uwimana E; Ruiz P; Li X; Lehmler HJ
    Environ Sci Technol; 2019 Feb; 53(4):2114-2123. PubMed ID: 30576102
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Atropselective Disposition of 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) and Identification of Its Metabolites in Mice with Liver-Specific Deletion of Cytochrome P450 Reductase.
    Wu X; Zhai G; Schnoor JL; Lehmler HJ
    Chem Res Toxicol; 2020 Jun; 33(6):1328-1338. PubMed ID: 31403789
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Toxicokinetics of Chiral PCB 136 and Its Hydroxylated Metabolites in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase.
    Li X; Wu X; Kelly KM; Veng-Pedersen P; Lehmler HJ
    Chem Res Toxicol; 2019 Apr; 32(4):727-736. PubMed ID: 30729780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of a novel hydroxylated metabolite of 2,2',3,5',6-pentachlorobiphenyl formed in whole poplar plants.
    Ma C; Zhai G; Wu H; Kania-Korwel I; Lehmler HJ; Schnoor JL
    Environ Sci Pollut Res Int; 2016 Feb; 23(3):2089-98. PubMed ID: 26676542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Editor's Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity.
    Kania-Korwel I; Lukasiewicz T; Barnhart CD; Stamou M; Chung H; Kelly KM; Bandiera S; Lein PJ; Lehmler HJ
    Toxicol Sci; 2017 Jul; 158(1):101-115. PubMed ID: 28431184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gas chromatographic analysis with chiral cyclodextrin phases reveals the enantioselective formation of hydroxylated polychlorinated biphenyls by rat liver microsomes.
    Kania-Korwel I; Duffel MW; Lehmler HJ
    Environ Sci Technol; 2011 Nov; 45(22):9590-6. PubMed ID: 21966948
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite.
    Uwimana E; Li X; Lehmler HJ
    Environ Sci Technol; 2018 May; 52(10):6000-6008. PubMed ID: 29659268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice.
    Wu X; Barnhart C; Lein PJ; Lehmler HJ
    Environ Sci Technol; 2015 Jan; 49(1):616-25. PubMed ID: 25420130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2,2',3,3',6,6'-Hexachlorobiphenyl (PCB 136) atropisomers interact enantioselectively with hepatic microsomal cytochrome P450 enzymes.
    Kania-Korwel I; Hrycay EG; Bandiera SM; Lehmler HJ
    Chem Res Toxicol; 2008 Jun; 21(6):1295-303. PubMed ID: 18494506
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes.
    Kania-Korwel I; Xie W; Hornbuckle KC; Robertson LW; Lehmler HJ
    Arch Environ Contam Toxicol; 2008 Oct; 55(3):510-7. PubMed ID: 18437444
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chiral polychlorinated biphenyls: absorption, metabolism and excretion--a review.
    Kania-Korwel I; Lehmler HJ
    Environ Sci Pollut Res Int; 2016 Feb; 23(3):2042-57. PubMed ID: 25651810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2,2',3,5',6-Pentachlorobiphenyl (PCB 95) and its hydroxylated metabolites are enantiomerically enriched in female mice.
    Kania-Korwel I; Barnhart CD; Stamou M; Truong KM; El-Komy MH; Lein PJ; Veng-Pedersen P; Lehmler HJ
    Environ Sci Technol; 2012 Oct; 46(20):11393-401. PubMed ID: 22974126
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stereoselective formation of mono- and dihydroxylated polychlorinated biphenyls by rat cytochrome P450 2B1.
    Lu Z; Kania-Korwel I; Lehmler HJ; Wong CS
    Environ Sci Technol; 2013; 47(21):12184-92. PubMed ID: 24060104
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.