BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 24117238)

  • 1. The regulatory mechanism of a client kinase controlling its own release from Hsp90 chaperone machinery through phosphorylation.
    Lu XA; Wang X; Zhuo W; Jia L; Jiang Y; Fu Y; Luo Y
    Biochem J; 2014 Jan; 457(1):171-83. PubMed ID: 24117238
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thr90 phosphorylation of Hsp90α by protein kinase A regulates its chaperone machinery.
    Wang X; Lu XA; Song X; Zhuo W; Jia L; Jiang Y; Luo Y
    Biochem J; 2012 Jan; 441(1):387-97. PubMed ID: 21919888
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chaperone Activity and Dimerization Properties of Hsp90
    Morishima Y; Mehta RK; Yoshimura M; Lau M; Southworth DR; Lawrence TS; Pratt WB; Nyati MK; Osawa Y
    Mol Pharmacol; 2018 Sep; 94(3):984-991. PubMed ID: 29941666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine.
    Xu W; Mollapour M; Prodromou C; Wang S; Scroggins BT; Palchick Z; Beebe K; Siderius M; Lee MJ; Couvillon A; Trepel JB; Miyata Y; Matts R; Neckers L
    Mol Cell; 2012 Aug; 47(3):434-43. PubMed ID: 22727666
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PLCγ1-PKCγ signaling-mediated Hsp90α plasma membrane translocation facilitates tumor metastasis.
    Yang J; Song X; Chen Y; Lu XA; Fu Y; Luo Y
    Traffic; 2014 Aug; 15(8):861-78. PubMed ID: 24899266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains.
    Czemeres J; Buse K; Verkhivker GM
    PLoS One; 2017; 12(12):e0190267. PubMed ID: 29267381
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans.
    Zuehlke AD; Reidy M; Lin C; LaPointe P; Alsomairy S; Lee DJ; Rivera-Marquez GM; Beebe K; Prince T; Lee S; Trepel JB; Xu W; Johnson J; Masison D; Neckers L
    Nat Commun; 2017 May; 8():15328. PubMed ID: 28537252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein kinase CK2 in health and disease: CK2: the kinase controlling the Hsp90 chaperone machinery.
    Miyata Y
    Cell Mol Life Sci; 2009 Jun; 66(11-12):1840-9. PubMed ID: 19387550
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte.
    Ota A; Zhang J; Ping P; Han J; Wang Y
    Circ Res; 2010 Apr; 106(8):1404-12. PubMed ID: 20299663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting CDC37: an alternative, kinase-directed strategy for disruption of oncogenic chaperoning.
    Smith JR; Workman P
    Cell Cycle; 2009 Feb; 8(3):362-72. PubMed ID: 19177013
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
    Gaude H; Aznar N; Delay A; Bres A; Buchet-Poyau K; Caillat C; Vigouroux A; Rogon C; Woods A; Vanacker JM; Höhfeld J; Perret C; Meyer P; Billaud M; Forcet C
    Oncogene; 2012 Mar; 31(12):1582-91. PubMed ID: 21860411
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery.
    Li T; Jiang HL; Tong YG; Lu JJ
    J Hematol Oncol; 2018 Apr; 11(1):59. PubMed ID: 29699578
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
    Li R; Yuan F; Fu W; Zhang L; Zhang N; Wang Y; Ma K; Li X; Wang L; Zhu WG; Zhao Y
    J Biol Chem; 2017 Feb; 292(7):2830-2841. PubMed ID: 28073914
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression and purification of recombinant NRL-Hsp90α and Cdc37-CRL proteins for in vitro Hsp90/Cdc37 inhibitors screening.
    He J; Niu X; Hu C; Zhang H; Guo Y; Ge Y; Wang G; Jiang Y
    Protein Expr Purif; 2013 Nov; 92(1):119-27. PubMed ID: 24056254
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation.
    Bachman AB; Keramisanou D; Xu W; Beebe K; Moses MA; Vasantha Kumar MV; Gray G; Noor RE; van der Vaart A; Neckers L; Gelis I
    Nat Commun; 2018 Jan; 9(1):265. PubMed ID: 29343704
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail.
    Gould CM; Kannan N; Taylor SS; Newton AC
    J Biol Chem; 2009 Feb; 284(8):4921-35. PubMed ID: 19091746
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity.
    Walton-Diaz A; Khan S; Bourboulia D; Trepel JB; Neckers L; Mollapour M
    Future Med Chem; 2013 Jun; 5(9):1059-71. PubMed ID: 23734688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional Role and Hierarchy of the Intermolecular Interactions in Binding of Protein Kinase Clients to the Hsp90-Cdc37 Chaperone: Structure-Based Network Modeling of Allosteric Regulation.
    Stetz G; Verkhivker GM
    J Chem Inf Model; 2018 Feb; 58(2):405-421. PubMed ID: 29432007
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent Manner.
    Gong Y; Wang C; Jiang Y; Zhang S; Feng S; Fu Y; Luo Y
    Cells; 2020 Jan; 9(1):. PubMed ID: 31936169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional specificity of co-chaperone interactions with Hsp90 client proteins.
    Riggs DL; Cox MB; Cheung-Flynn J; Prapapanich V; Carrigan PE; Smith DF
    Crit Rev Biochem Mol Biol; 2004; 39(5-6):279-95. PubMed ID: 15763706
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.