BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 24121277)

  • 1. Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells.
    Venere M; Hamerlik P; Wu Q; Rasmussen RD; Song LA; Vasanji A; Tenley N; Flavahan WA; Hjelmeland AB; Bartek J; Rich JN
    Cell Death Differ; 2014 Feb; 21(2):258-69. PubMed ID: 24121277
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rad51 Degradation: Role in Oncolytic Virus-Poly(ADP-Ribose) Polymerase Inhibitor Combination Therapy in Glioblastoma.
    Ning J; Wakimoto H; Peters C; Martuza RL; Rabkin SD
    J Natl Cancer Inst; 2017 Mar; 109(3):1-13. PubMed ID: 28376211
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
    Rasmussen RD; Gajjar MK; Jensen KE; Hamerlik P
    Mol Oncol; 2016 May; 10(5):751-63. PubMed ID: 26794465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PARP-1 inhibition with or without ionizing radiation confers reactive oxygen species-mediated cytotoxicity preferentially to cancer cells with mutant TP53.
    Liu Q; Gheorghiu L; Drumm M; Clayman R; Eidelman A; Wszolek MF; Olumi A; Feldman A; Wang M; Marcar L; Citrin DE; Wu CL; Benes CH; Efstathiou JA; Willers H
    Oncogene; 2018 May; 37(21):2793-2805. PubMed ID: 29511347
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.
    Tentori L; Ricci-Vitiani L; Muzi A; Ciccarone F; Pelacchi F; Calabrese R; Runci D; Pallini R; Caiafa P; Graziani G
    BMC Cancer; 2014 Mar; 14():151. PubMed ID: 24593254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.
    Wiltshire TD; Lovejoy CA; Wang T; Xia F; O'Connor MJ; Cortez D
    J Biol Chem; 2010 May; 285(19):14565-71. PubMed ID: 20233726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma.
    Karpel-Massler G; Pareja F; Aimé P; Shu C; Chau L; Westhoff MA; Halatsch ME; Crary JF; Canoll P; Siegelin MD
    PLoS One; 2014; 9(12):e114583. PubMed ID: 25531448
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.
    Yuan B; Ye N; Song SS; Wang YT; Song Z; Chen HD; Chen CH; Huan XJ; Wang YQ; Su Y; Shen YY; Sun YM; Yang XY; Chen Y; Guo SY; Gan Y; Gao ZW; Chen XY; Ding J; He JX; Zhang A; Miao ZH
    Cancer Lett; 2017 Feb; 386():47-56. PubMed ID: 27847302
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Restoration of Temozolomide Sensitivity by PARP Inhibitors in Mismatch Repair Deficient Glioblastoma is Independent of Base Excision Repair.
    Higuchi F; Nagashima H; Ning J; Koerner MVA; Wakimoto H; Cahill DP
    Clin Cancer Res; 2020 Apr; 26(7):1690-1699. PubMed ID: 31900275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PARP-1 inhibition induces a late increase in the level of reactive oxygen species in cells after ionizing radiation.
    Cieślar-Pobuda A; Saenko Y; Rzeszowska-Wolny J
    Mutat Res; 2012 Apr; 732(1-2):9-15. PubMed ID: 22321899
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways.
    Bijangi-Vishehsaraei K; Reza Saadatzadeh M; Wang H; Nguyen A; Kamocka MM; Cai W; Cohen-Gadol AA; Halum SL; Sarkaria JN; Pollok KE; Safa AR
    J Neurosurg; 2017 Dec; 127(6):1219-1230. PubMed ID: 28059653
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma.
    Singer E; Judkins J; Salomonis N; Matlaf L; Soteropoulos P; McAllister S; Soroceanu L
    Cell Death Dis; 2015 Jan; 6(1):e1601. PubMed ID: 25590811
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.
    Min A; Im SA; Kim DK; Song SH; Kim HJ; Lee KH; Kim TY; Han SW; Oh DY; Kim TY; O'Connor MJ; Bang YJ
    Breast Cancer Res; 2015 Mar; 17():33. PubMed ID: 25888415
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Replication Stress Drives Constitutive Activation of the DNA Damage Response and Radioresistance in Glioblastoma Stem-like Cells.
    Carruthers RD; Ahmed SU; Ramachandran S; Strathdee K; Kurian KM; Hedley A; Gomez-Roman N; Kalna G; Neilson M; Gilmour L; Stevenson KH; Hammond EM; Chalmers AJ
    Cancer Res; 2018 Sep; 78(17):5060-5071. PubMed ID: 29976574
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacologic characterization of fluzoparib, a novel poly(ADP-ribose) polymerase inhibitor undergoing clinical trials.
    Wang L; Yang C; Xie C; Jiang J; Gao M; Fu L; Li Y; Bao X; Fu H; Lou L
    Cancer Sci; 2019 Mar; 110(3):1064-1075. PubMed ID: 30663191
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200.
    Fu J; Rodova M; Nanta R; Meeker D; Van Veldhuizen PJ; Srivastava RK; Shankar S
    Neuro Oncol; 2013 Jun; 15(6):691-706. PubMed ID: 23482671
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
    Lin PH; Lin CH; Huang CC; Chuang MC; Lin P
    Toxicol Lett; 2007 Aug; 172(3):146-58. PubMed ID: 17669606
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation.
    Hirai T; Shirai H; Fujimori H; Okayasu R; Sasai K; Masutani M
    Cancer Sci; 2012 Jun; 103(6):1045-50. PubMed ID: 22404155
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Co-targeting poly(ADP-ribose) polymerase (PARP) and histone deacetylase (HDAC) in triple-negative breast cancer: Higher synergism in BRCA mutated cells.
    Marijon H; Lee DH; Ding L; Sun H; Gery S; de Gramont A; Koeffler HP
    Biomed Pharmacother; 2018 Mar; 99():543-551. PubMed ID: 29902865
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly(ADP-Ribose) Polymerase Inhibition Sensitizes Colorectal Cancer-Initiating Cells to Chemotherapy.
    Jarrar A; Lotti F; DeVecchio J; Ferrandon S; Gantt G; Mace A; Karagkounis G; Orloff M; Venere M; Hitomi M; Lathia J; Rich JN; Kalady MF
    Stem Cells; 2019 Jan; 37(1):42-53. PubMed ID: 30353615
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.