These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
355 related articles for article (PubMed ID: 24127294)
1. Design and generation of highly diverse fluorinated fragment libraries and their efficient screening with improved (19) F NMR methodology. Vulpetti A; Dalvit C ChemMedChem; 2013 Dec; 8(12):2057-69. PubMed ID: 24127294 [TBL] [Abstract][Full Text] [Related]
2. Fluorine local environment: from screening to drug design. Vulpetti A; Dalvit C Drug Discov Today; 2012 Aug; 17(15-16):890-7. PubMed ID: 22480871 [TBL] [Abstract][Full Text] [Related]
3. Design and NMR-based screening of LEF, a library of chemical fragments with different local environment of fluorine. Vulpetti A; Hommel U; Landrum G; Lewis R; Dalvit C J Am Chem Soc; 2009 Sep; 131(36):12949-59. PubMed ID: 19702332 [TBL] [Abstract][Full Text] [Related]
4. Combined use of computational chemistry, NMR screening, and X-ray crystallography for identification and characterization of fluorophilic protein environments. Vulpetti A; Schiering N; Dalvit C Proteins; 2010 Dec; 78(16):3281-91. PubMed ID: 20886466 [TBL] [Abstract][Full Text] [Related]
6. Practical aspects of NMR-based fragment screening. Lepre CA Methods Enzymol; 2011; 493():219-39. PubMed ID: 21371593 [TBL] [Abstract][Full Text] [Related]
7. Efficient Screening of Target-Specific Selected Compounds in Mixtures by Vulpetti A; Lingel A; Dalvit C; Schiering N; Oberer L; Henry C; Lu Y ChemMedChem; 2022 Jul; 17(13):e202200163. PubMed ID: 35475323 [TBL] [Abstract][Full Text] [Related]
8. A combination of Nagatoishi S; Yamaguchi S; Katoh E; Kajita K; Yokotagawa T; Kanai S; Furuya T; Tsumoto K Bioorg Med Chem; 2018 May; 26(8):1929-1938. PubMed ID: 29510947 [No Abstract] [Full Text] [Related]
9. Fast and Efficient Fragment-Based Lead Generation by Fully Automated Processing and Analysis of Ligand-Observed NMR Binding Data. Peng C; Frommlet A; Perez M; Cobas C; Blechschmidt A; Dominguez S; Lingel A J Med Chem; 2016 Apr; 59(7):3303-10. PubMed ID: 26964888 [TBL] [Abstract][Full Text] [Related]
10. Fragment based drug discovery: practical implementation based on ¹⁹F NMR spectroscopy. Jordan JB; Poppe L; Xia X; Cheng AC; Sun Y; Michelsen K; Eastwood H; Schnier PD; Nixey T; Zhong W J Med Chem; 2012 Jan; 55(2):678-87. PubMed ID: 22165820 [TBL] [Abstract][Full Text] [Related]
11. Advancing fragment binders to lead-like compounds using ligand and protein-based NMR spectroscopy. Maurer T Methods Enzymol; 2011; 493():469-85. PubMed ID: 21371602 [TBL] [Abstract][Full Text] [Related]
12. Technical and practical aspects of (19) F NMR-based screening: toward sensitive high-throughput screening with rapid deconvolution. Dalvit C; Vulpetti A Magn Reson Chem; 2012 Sep; 50(9):592-7. PubMed ID: 22821476 [TBL] [Abstract][Full Text] [Related]
13. Development of fragment-based n-FABS NMR screening applied to the membrane enzyme FAAH. Lambruschini C; Veronesi M; Romeo E; Garau G; Bandiera T; Piomelli D; Scarpelli R; Dalvit C Chembiochem; 2013 Sep; 14(13):1611-9. PubMed ID: 23918626 [TBL] [Abstract][Full Text] [Related]
14. QM assisted ML for Penner P; Vulpetti A J Comput Aided Mol Des; 2023 Dec; 38(1):4. PubMed ID: 38082055 [TBL] [Abstract][Full Text] [Related]
16. Comprehensive and High-Throughput Exploration of Chemical Space Using Broadband Lingel A; Vulpetti A; Reinsperger T; Proudfoot A; Denay R; Frommlet A; Henry C; Hommel U; Gossert AD; Luy B; Frank AO Angew Chem Int Ed Engl; 2020 Aug; 59(35):14809-14817. PubMed ID: 32363632 [TBL] [Abstract][Full Text] [Related]
17. Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors. Wang YS; Strickland C; Voigt JH; Kennedy ME; Beyer BM; Senior MM; Smith EM; Nechuta TL; Madison VS; Czarniecki M; McKittrick BA; Stamford AW; Parker EM; Hunter JC; Greenlee WJ; Wyss DF J Med Chem; 2010 Feb; 53(3):942-50. PubMed ID: 20043700 [TBL] [Abstract][Full Text] [Related]
19. Alternate strategies to obtain mass balance without the use of radiolabeled compounds: application of quantitative fluorine (19F) nuclear magnetic resonance (NMR) spectroscopy in metabolism studies. Mutlib A; Espina R; Atherton J; Wang J; Talaat R; Scatina J; Chandrasekaran A Chem Res Toxicol; 2012 Mar; 25(3):572-83. PubMed ID: 22292524 [TBL] [Abstract][Full Text] [Related]
20. Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins. Tengel T; Fex T; Emtenas H; Almqvist F; Sethson I; Kihlberg J Org Biomol Chem; 2004 Mar; 2(5):725-31. PubMed ID: 14985813 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]