BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 24127404)

  • 1. Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes.
    Yoon JH; Jung SM; Park SH; Kato M; Yamashita T; Lee IK; Sudo K; Nakae S; Han JS; Kim OH; Oh BC; Sumida T; Kuroda M; Ju JH; Jung KC; Park SH; Kim DK; Mamura M
    EMBO Mol Med; 2013 Nov; 5(11):1720-39. PubMed ID: 24127404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transforming growth factor-beta- and Activin-Smad signaling pathways are activated at distinct maturation stages of the thymopoeisis.
    Rosendahl A; Speletas M; Leandersson K; Ivars F; Sideras P
    Int Immunol; 2003 Dec; 15(12):1401-14. PubMed ID: 14645149
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cells.
    Chen YC; Chang HM; Cheng JC; Tsai HD; Wu CH; Leung PC
    Hum Reprod; 2015 Sep; 30(9):2190-201. PubMed ID: 26202915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.
    Mazerbourg S; Klein C; Roh J; Kaivo-Oja N; Mottershead DG; Korchynskyi O; Ritvos O; Hsueh AJ
    Mol Endocrinol; 2004 Mar; 18(3):653-65. PubMed ID: 14684852
    [TBL] [Abstract][Full Text] [Related]  

  • 5. EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells.
    Park CY; Kim DK; Sheen YY
    Cancer Sci; 2011 Oct; 102(10):1889-96. PubMed ID: 21707864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TGF-beta-mediated activation of RhoA signalling is required for efficient (V12)HaRas and (V600E)BRAF transformation.
    Fleming YM; Ferguson GJ; Spender LC; Larsson J; Karlsson S; Ozanne BW; Grosse R; Inman GJ
    Oncogene; 2009 Feb; 28(7):983-93. PubMed ID: 19079344
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth.
    Daly AC; Randall RA; Hill CS
    Mol Cell Biol; 2008 Nov; 28(22):6889-902. PubMed ID: 18794361
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5.
    Zeeh F; Witte D; Gädeken T; Rauch BH; Grage-Griebenow E; Leinung N; Fromm SJ; Stölting S; Mihara K; Kaufmann R; Settmacher U; Lehnert H; Hollenberg MD; Ungefroren H
    Oncotarget; 2016 Jul; 7(27):41095-41109. PubMed ID: 27248167
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endothelial fibrosis induced by suppressed STAT3 expression mediated by signaling involving the TGF-β1/ALK5/Smad pathway.
    Becerra A; Rojas M; Vallejos A; Villegas V; Pérez L; Cabello-Verrugio C; Simon F
    Lab Invest; 2017 Sep; 97(9):1033-1046. PubMed ID: 28737766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transforming growth factor-beta1 protects against pulmonary artery endothelial cell apoptosis via ALK5.
    Lu Q
    Am J Physiol Lung Cell Mol Physiol; 2008 Jul; 295(1):L123-33. PubMed ID: 18456797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
    Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intracellular TGF-beta receptor blockade abrogates Smad-dependent fibroblast activation in vitro and in vivo.
    Ishida W; Mori Y; Lakos G; Sun L; Shan F; Bowes S; Josiah S; Lee WC; Singh J; Ling LE; Varga J
    J Invest Dermatol; 2006 Aug; 126(8):1733-44. PubMed ID: 16741519
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimetastatic role of Smad4 signaling in colorectal cancer.
    Zhang B; Halder SK; Kashikar ND; Cho YJ; Datta A; Gorden DL; Datta PK
    Gastroenterology; 2010 Mar; 138(3):969-80.e1-3. PubMed ID: 19909744
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isothiocyanate sulforaphane inhibits protooncogenic ornithine decarboxylase activity in colorectal cancer cells via induction of the TGF-β/Smad signaling pathway.
    Kaminski BM; Loitsch SM; Ochs MJ; Reuter KC; Steinhilber D; Stein J; Ulrich S
    Mol Nutr Food Res; 2010 Oct; 54(10):1486-96. PubMed ID: 20603835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PDZK1-interacting protein 1 (PDZK1IP1) traps Smad4 protein and suppresses transforming growth factor-β (TGF-β) signaling.
    Ikeno S; Nakano N; Sano K; Minowa T; Sato W; Akatsu R; Sakata N; Hanagata N; Fujii M; Itoh F; Itoh S
    J Biol Chem; 2019 Mar; 294(13):4966-4980. PubMed ID: 30718277
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sonic hedgehog signaling promotes motility and invasiveness of gastric cancer cells through TGF-beta-mediated activation of the ALK5-Smad 3 pathway.
    Yoo YA; Kang MH; Kim JS; Oh SC
    Carcinogenesis; 2008 Mar; 29(3):480-90. PubMed ID: 18174246
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transforming growth factor-beta (TGF-beta) type I receptor/ALK5-dependent activation of the GADD45beta gene mediates the induction of biglycan expression by TGF-beta.
    Ungefroren H; Groth S; Ruhnke M; Kalthoff H; Fändrich F
    J Biol Chem; 2005 Jan; 280(4):2644-52. PubMed ID: 15546867
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling.
    Wicks SJ; Haros K; Maillard M; Song L; Cohen RE; Dijke PT; Chantry A
    Oncogene; 2005 Dec; 24(54):8080-4. PubMed ID: 16027725
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells.
    Huo YY; Hu YC; He XR; Wang Y; Song BQ; Zhou PK; Zhu MX; Li G; Wu DC
    Cell Biol Toxicol; 2007 Mar; 23(2):113-28. PubMed ID: 17096210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.