222 related articles for article (PubMed ID: 24130096)
21. Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.
Eggler AL; Small E; Hannink M; Mesecar AD
Biochem J; 2009 Jul; 422(1):171-80. PubMed ID: 19489739
[TBL] [Abstract][Full Text] [Related]
22. Recent progress in Keap1-Nrf2 protein-protein interaction inhibitors.
Mou Y; Wen S; Li YX; Gao XX; Zhang X; Jiang ZY
Eur J Med Chem; 2020 Sep; 202():112532. PubMed ID: 32668381
[TBL] [Abstract][Full Text] [Related]
23. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
Jain A; Lamark T; Sjøttem E; Larsen KB; Awuh JA; Øvervatn A; McMahon M; Hayes JD; Johansen T
J Biol Chem; 2010 Jul; 285(29):22576-91. PubMed ID: 20452972
[TBL] [Abstract][Full Text] [Related]
24. Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.
Jiang ZY; Lu MC; Xu LL; Yang TT; Xi MY; Xu XL; Guo XK; Zhang XJ; You QD; Sun HP
J Med Chem; 2014 Mar; 57(6):2736-45. PubMed ID: 24512214
[TBL] [Abstract][Full Text] [Related]
25. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
26. Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Zhong M; Lynch A; Muellers SN; Jehle S; Luo L; Hall DR; Iwase R; Carolan JP; Egbert M; Wakefield A; Streu K; Harvey CM; Ortet PC; Kozakov D; Vajda S; Allen KN; Whitty A
Biochemistry; 2020 Feb; 59(4):563-581. PubMed ID: 31851823
[TBL] [Abstract][Full Text] [Related]
27. Cysteine-based regulation of the CUL3 adaptor protein Keap1.
Sekhar KR; Rachakonda G; Freeman ML
Toxicol Appl Pharmacol; 2010 Apr; 244(1):21-6. PubMed ID: 19560482
[TBL] [Abstract][Full Text] [Related]
28. Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.
Tong KI; Padmanabhan B; Kobayashi A; Shang C; Hirotsu Y; Yokoyama S; Yamamoto M
Mol Cell Biol; 2007 Nov; 27(21):7511-21. PubMed ID: 17785452
[TBL] [Abstract][Full Text] [Related]
29. Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3.
Hayes JD; Chowdhry S; Dinkova-Kostova AT; Sutherland C
Biochem Soc Trans; 2015 Aug; 43(4):611-20. PubMed ID: 26551701
[TBL] [Abstract][Full Text] [Related]
30. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
Baird L; Dinkova-Kostova AT
Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
[TBL] [Abstract][Full Text] [Related]
31. The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway.
Edwards MR; Johnson B; Mire CE; Xu W; Shabman RS; Speller LN; Leung DW; Geisbert TW; Amarasinghe GK; Basler CF
Cell Rep; 2014 Mar; 6(6):1017-1025. PubMed ID: 24630991
[TBL] [Abstract][Full Text] [Related]
32. Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery.
Madden SK; Itzhaki LS
Biochim Biophys Acta Proteins Proteom; 2020 Jul; 1868(7):140405. PubMed ID: 32120017
[TBL] [Abstract][Full Text] [Related]
33. Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.
Tong KI; Katoh Y; Kusunoki H; Itoh K; Tanaka T; Yamamoto M
Mol Cell Biol; 2006 Apr; 26(8):2887-900. PubMed ID: 16581765
[TBL] [Abstract][Full Text] [Related]
34. Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases.
Pallesen JS; Tran KT; Bach A
J Med Chem; 2018 Sep; 61(18):8088-8103. PubMed ID: 29750408
[TBL] [Abstract][Full Text] [Related]
35. Molecular basis for the disruption of Keap1-Nrf2 interaction via Hinge & Latch mechanism.
Horie Y; Suzuki T; Inoue J; Iso T; Wells G; Moore TW; Mizushima T; Dinkova-Kostova AT; Kasai T; Kamei T; Koshiba S; Yamamoto M
Commun Biol; 2021 May; 4(1):576. PubMed ID: 33990683
[TBL] [Abstract][Full Text] [Related]
36. Measuring the Interaction of Transcription Factor Nrf2 with Its Negative Regulator Keap1 in Single Live Cells by an Improved FRET/FLIM Analysis.
Dikovskaya D; Appleton PL; Bento-Pereira C; Dinkova-Kostova AT
Chem Res Toxicol; 2019 Mar; 32(3):500-512. PubMed ID: 30793592
[TBL] [Abstract][Full Text] [Related]
37. Screening approaches for the identification of Nrf2-Keap1 protein-protein interaction inhibitors targeting hot spot residues.
Asano W; Hantani R; Uhara T; Debaene F; Nomura A; Yamaguchi K; Adachi T; Otake K; Harada K; Hantani Y
SLAS Discov; 2024 Mar; 29(2):100125. PubMed ID: 37935317
[TBL] [Abstract][Full Text] [Related]
38. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
[TBL] [Abstract][Full Text] [Related]
39. USP15 negatively regulates Nrf2 through deubiquitination of Keap1.
Villeneuve NF; Tian W; Wu T; Sun Z; Lau A; Chapman E; Fang D; Zhang DD
Mol Cell; 2013 Jul; 51(1):68-79. PubMed ID: 23727018
[TBL] [Abstract][Full Text] [Related]
40. Rational cyclization-based minimization of entropy penalty upon the binding of Nrf2-derived linear peptides to Keap1: A new strategy to improve therapeutic peptide activity against sepsis.
Chen K; Huang L; Shen B
Biophys Chem; 2019 Jan; 244():22-28. PubMed ID: 30465941
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
