BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 24132751)

  • 1. Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals.
    Liang ZD; Long Y; Chen HH; Savaraj N; Kuo MT
    J Biol Inorg Chem; 2014 Jan; 19(1):17-27. PubMed ID: 24132751
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overcoming platinum drug resistance with copper-lowering agents.
    Chen HH; Kuo MT
    Anticancer Res; 2013 Oct; 33(10):4157-61. PubMed ID: 24122978
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of the human high-affinity copper transporter in copper homeostasis regulation and cisplatin sensitivity in cancer chemotherapy.
    Kuo MT; Fu S; Savaraj N; Chen HH
    Cancer Res; 2012 Sep; 72(18):4616-21. PubMed ID: 22962276
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells.
    Song IS; Savaraj N; Siddik ZH; Liu P; Wei Y; Wu CJ; Kuo MT
    Mol Cancer Ther; 2004 Dec; 3(12):1543-9. PubMed ID: 15634647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A re-evaluation of the role of hCTR1, the human high-affinity copper transporter, in platinum-drug entry into human cells.
    Ivy KD; Kaplan JH
    Mol Pharmacol; 2013 Jun; 83(6):1237-46. PubMed ID: 23543413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy.
    Chen HH; Chen WC; Liang ZD; Tsai WB; Long Y; Aiba I; Fu S; Broaddus R; Liu J; Feun LG; Savaraj N; Kuo MT
    Expert Opin Ther Targets; 2015; 19(10):1307-17. PubMed ID: 26004625
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1.
    Chen HH; Song IS; Hossain A; Choi MK; Yamane Y; Liang ZD; Lu J; Wu LY; Siddik ZH; Klomp LW; Savaraj N; Kuo MT
    Mol Pharmacol; 2008 Sep; 74(3):697-704. PubMed ID: 18523133
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Specificity protein 1 (sp1) oscillation is involved in copper homeostasis maintenance by regulating human high-affinity copper transporter 1 expression.
    Liang ZD; Tsai WB; Lee MY; Savaraj N; Kuo MT
    Mol Pharmacol; 2012 Mar; 81(3):455-64. PubMed ID: 22172574
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulating Chemosensitivity of Tumors to Platinum-Based Antitumor Drugs by Transcriptional Regulation of Copper Homeostasis.
    Lai YH; Kuo C; Kuo MT; Chen HHW
    Int J Mol Sci; 2018 May; 19(5):. PubMed ID: 29772714
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1.
    Wu Z; Liu Q; Liang X; Yang X; Wang N; Wang X; Sun H; Lu Y; Guo Z
    J Biol Inorg Chem; 2009 Nov; 14(8):1313-23. PubMed ID: 19669174
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic basis for overcoming platinum resistance using copper chelating agents.
    Liang ZD; Long Y; Tsai WB; Fu S; Kurzrock R; Gagea-Iurascu M; Zhang F; Chen HH; Hennessy BT; Mills GB; Savaraj N; Kuo MT
    Mol Cancer Ther; 2012 Nov; 11(11):2483-94. PubMed ID: 22914438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The copper influx transporter human copper transport protein 1 regulates the uptake of cisplatin in human ovarian carcinoma cells.
    Holzer AK; Samimi G; Katano K; Naerdemann W; Lin X; Safaei R; Howell SB
    Mol Pharmacol; 2004 Oct; 66(4):817-23. PubMed ID: 15229296
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters.
    Guo Y; Smith K; Petris MJ
    J Biol Chem; 2004 Nov; 279(45):46393-9. PubMed ID: 15326162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic comparison of human high-affinity copper transporter 1-mediated transport between copper ion and cisplatin.
    Liang ZD; Stockton D; Savaraj N; Tien Kuo M
    Mol Pharmacol; 2009 Oct; 76(4):843-53. PubMed ID: 19570948
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The roles of copper transporters in cisplatin resistance.
    Kuo MT; Chen HH; Song IS; Savaraj N; Ishikawa T
    Cancer Metastasis Rev; 2007 Mar; 26(1):71-83. PubMed ID: 17318448
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison between copper and cisplatin transport mediated by human copper transporter 1 (hCTR1).
    Du X; Wang X; Li H; Sun H
    Metallomics; 2012 Jul; 4(7):679-85. PubMed ID: 22552365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatin.
    Larson CA; Adams PL; Blair BG; Safaei R; Howell SB
    Mol Pharmacol; 2010 Sep; 78(3):333-9. PubMed ID: 20519567
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of Cu(II) and cisplatin on the stability of Specific protein 1 (Sp1)-DNA binding: Insights into the regulation of copper homeostasis and platinum drug transport.
    Yan D; Aiba I; Chen HH; Kuo MT
    J Inorg Biochem; 2016 Aug; 161():37-9. PubMed ID: 27172866
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity.
    Cui H; Zhang AJ; McKeage MJ; Nott LM; Geraghty D; Guven N; Liu JJ
    J Inorg Biochem; 2017 Dec; 177():249-258. PubMed ID: 28551160
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcription factor Sp1 plays an important role in the regulation of copper homeostasis in mammalian cells.
    Song IS; Chen HH; Aiba I; Hossain A; Liang ZD; Klomp LW; Kuo MT
    Mol Pharmacol; 2008 Sep; 74(3):705-13. PubMed ID: 18483225
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.