These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
164 related articles for article (PubMed ID: 24135727)
1. Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors. Bondada L; Rondla R; Pradere U; Liu P; Li C; Bobeck D; McBrayer T; Tharnish P; Courcambeck J; Halfon P; Whitaker T; Amblard F; Coats SJ; Schinazi RF Bioorg Med Chem Lett; 2013 Dec; 23(23):6325-30. PubMed ID: 24135727 [TBL] [Abstract][Full Text] [Related]
2. Phosphorous acid analogs of novel P2-P4 macrocycles as inhibitors of HCV-NS3 protease. Pompei M; Francesco ME; Koch U; Liverton NJ; Summa V Bioorg Med Chem Lett; 2009 May; 19(9):2574-8. PubMed ID: 19328685 [TBL] [Abstract][Full Text] [Related]
3. Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease. Parsy C; Alexandre FR; Brandt G; Caillet C; Cappelle S; Chaves D; Convard T; Derock M; Gloux D; Griffon Y; Lallos L; Leroy F; Liuzzi M; Loi AG; Moulat L; Musiu C; Rahali H; Roques V; Seifer M; Standring D; Surleraux D Bioorg Med Chem Lett; 2014 Sep; 24(18):4444-4449. PubMed ID: 25155387 [TBL] [Abstract][Full Text] [Related]
4. The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors. Romano KP; Ali A; Aydin C; Soumana D; Ozen A; Deveau LM; Silver C; Cao H; Newton A; Petropoulos CJ; Huang W; Schiffer CA PLoS Pathog; 2012; 8(7):e1002832. PubMed ID: 22910833 [TBL] [Abstract][Full Text] [Related]
6. Structure-activity study on a novel series of macrocyclic inhibitors of the hepatitis C virus NS3 protease leading to the discovery of BILN 2061. Llinàs-Brunet M; Bailey MD; Bolger G; Brochu C; Faucher AM; Ferland JM; Garneau M; Ghiro E; Gorys V; Grand-Maître C; Halmos T; Lapeyre-Paquette N; Liard F; Poirier M; Rhéaume M; Tsantrizos YS; Lamarre D J Med Chem; 2004 Mar; 47(7):1605-8. PubMed ID: 15027850 [TBL] [Abstract][Full Text] [Related]
7. Challenges in modern drug discovery: a case study of boceprevir, an HCV protease inhibitor for the treatment of hepatitis C virus infection. Njoroge FG; Chen KX; Shih NY; Piwinski JJ Acc Chem Res; 2008 Jan; 41(1):50-9. PubMed ID: 18193821 [TBL] [Abstract][Full Text] [Related]
8. Identification of novel small molecule inhibitors against the NS3/4A protease of hepatitis C virus genotype 4a. El-Sayed SM; Ali MAM; El-Gendy BEM; Dandash SS; Issac Y; Saad R; Azab MM; Mohamed MR Curr Pharm Des; 2018; 24(37):4484-4491. PubMed ID: 30501598 [TBL] [Abstract][Full Text] [Related]
9. Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors. Nair LG; Bogen S; Ruan S; Pan W; Pike R; Tong X; Cheng KC; Guo Z; Doll RJ; Njoroge FG Bioorg Med Chem Lett; 2010 Mar; 20(5):1689-92. PubMed ID: 20149655 [TBL] [Abstract][Full Text] [Related]
10. The Journey to the Discovery of Boceprevir: an NS3-NS4 HCV protease inhibitor for the treatment of chronic hepatitis C. Chen KX; Njoroge FG Prog Med Chem; 2010; 49():1-36. PubMed ID: 20855037 [No Abstract] [Full Text] [Related]
11. Computational Modelling in Studies for Hepatitis C Virus (HCV) NS3 Protease. Mukhametov A Curr Top Med Chem; 2016; 16(12):1351-61. PubMed ID: 26585936 [TBL] [Abstract][Full Text] [Related]
12. Potent ketoamide inhibitors of HCV NS3 protease derived from quaternized P1 groups. Venkatraman S; Velazquez F; Wu W; Blackman M; Madison V; Njoroge FG Bioorg Med Chem Lett; 2010 Apr; 20(7):2151-5. PubMed ID: 20226659 [TBL] [Abstract][Full Text] [Related]
13. Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H)-pyrazinones. Ortqvist P; Gising J; Ehrenberg AE; Vema A; Borg A; Karlén A; Larhed M; Danielson UH; Sandström A Bioorg Med Chem; 2010 Sep; 18(17):6512-25. PubMed ID: 20673728 [TBL] [Abstract][Full Text] [Related]
14. Synthesis and optimization of a novel series of HCV NS3 protease inhibitors: 4-arylproline analogs. Bilodeau F; Bailey MD; Bhardwaj PK; Bordeleau J; Forgione P; Garneau M; Ghiro E; Gorys V; Halmos T; Jolicoeur ES; Leblanc M; Lemke CT; Naud J; O'Meara J; White PW; Llinàs-Brunet M Bioorg Med Chem Lett; 2013 Jul; 23(14):4267-71. PubMed ID: 23735741 [TBL] [Abstract][Full Text] [Related]
15. Synthesis and antiviral activity of HCV NS3/4A peptidomimetic boronic acid inhibitors. Boloor A; Hanway D; Joshi M; Winn DT; Mendez G; Walls M; Wei P; Qian F; Zhang X; Zhang Y; Hepperle ME; Li X; Campbell DA; Betancort JM Bioorg Med Chem Lett; 2009 Oct; 19(19):5708-11. PubMed ID: 19713109 [TBL] [Abstract][Full Text] [Related]
16. Simultaneously Targeting the NS3 Protease and Helicase Activities for More Effective Hepatitis C Virus Therapy. Ndjomou J; Corby MJ; Sweeney NL; Hanson AM; Aydin C; Ali A; Schiffer CA; Li K; Frankowski KJ; Schoenen FJ; Frick DN ACS Chem Biol; 2015 Aug; 10(8):1887-96. PubMed ID: 25961497 [TBL] [Abstract][Full Text] [Related]
17. Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design. Venkatraman S; Njoroge FG; Girijavallabhan VM; Madison VS; Yao NH; Prongay AJ; Butkiewicz N; Pichardo J J Med Chem; 2005 Aug; 48(16):5088-91. PubMed ID: 16078825 [TBL] [Abstract][Full Text] [Related]
18. Exploring the P2 and P3 ligand binding features for hepatitis C virus NS3 protease using some 3D QSAR techniques. Wei HY; Lu CS; Lin TH J Mol Graph Model; 2008 Apr; 26(7):1131-44. PubMed ID: 18024210 [TBL] [Abstract][Full Text] [Related]
19. Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors. Ortqvist P; Peterson SD; Kerblom E; Gossas T; Sabnis YA; Fransson R; Lindeberg G; Helena Danielson U; Karlén A; Sandström A Bioorg Med Chem; 2007 Feb; 15(3):1448-74. PubMed ID: 17113777 [TBL] [Abstract][Full Text] [Related]
20. Peptide inhibitors of hepatitis C virus NS3 protease. Portal-Núñez S; González-Navarro CJ; García-Delgado M; Vizmanos JL; Lasarte JJ; Borrás-Cuesta F Antivir Chem Chemother; 2003 Sep; 14(5):225-33. PubMed ID: 14694985 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]