BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

481 related articles for article (PubMed ID: 24140020)

  • 1. mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc.
    Masui K; Tanaka K; Akhavan D; Babic I; Gini B; Matsutani T; Iwanami A; Liu F; Villa GR; Gu Y; Campos C; Zhu S; Yang H; Yong WH; Cloughesy TF; Mellinghoff IK; Cavenee WK; Shaw RJ; Mischel PS
    Cell Metab; 2013 Nov; 18(5):726-39. PubMed ID: 24140020
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mTORC2 dictates Warburg effect and drug resistance.
    Masui K; Cavenee WK; Mischel PS
    Cell Cycle; 2014; 13(7):1053-4. PubMed ID: 24583874
    [No Abstract]   [Full Text] [Related]  

  • 3. Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition.
    Singh BK; Sinha RA; Zhou J; Tripathi M; Ohba K; Wang ME; Astapova I; Ghosh S; Hollenberg AN; Gauthier K; Yen PM
    J Biol Chem; 2016 Jan; 291(1):198-214. PubMed ID: 26453307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance.
    Masui K; Tanaka K; Ikegami S; Villa GR; Yang H; Yong WH; Cloughesy TF; Yamagata K; Arai N; Cavenee WK; Mischel PS
    Proc Natl Acad Sci U S A; 2015 Jul; 112(30):9406-11. PubMed ID: 26170313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian Target of Rapamycin 2 (MTOR2) and C-MYC Modulate Glucosamine-6-Phosphate Synthesis in Glioblastoma (GBM) Cells Through Glutamine: Fructose-6-Phosphate Aminotransferase 1 (GFAT1).
    Liu B; Huang ZB; Chen X; See YX; Chen ZK; Yao HK
    Cell Mol Neurobiol; 2019 Apr; 39(3):415-434. PubMed ID: 30771196
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity.
    Jimenez L; Amenabar C; Mayoral-Varo V; Mackenzie TA; Ramos MC; Silva A; Calissi G; Grenho I; Blanco-Aparicio C; Pastor J; Megías D; Ferreira BI; Link W
    Molecules; 2022 Aug; 27(17):. PubMed ID: 36080182
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity.
    Sunayama J; Sato A; Matsuda K; Tachibana K; Watanabe E; Seino S; Suzuki K; Narita Y; Shibui S; Sakurada K; Kayama T; Tomiyama A; Kitanaka C
    Stem Cells; 2011 Sep; 29(9):1327-37. PubMed ID: 21793107
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
    Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness.
    Artinian N; Cloninger C; Holmes B; Benavides-Serrato A; Bashir T; Gera J
    J Biol Chem; 2015 Aug; 290(32):19387-401. PubMed ID: 25998128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M
    Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PI3K Pathway Inhibition with NVP-BEZ235 Hinders Glycolytic Metabolism in Glioblastoma Multiforme Cells.
    Udawant S; Litif C; Lopez A; Gunn B; Schuenzel E; Keniry M
    Cells; 2021 Nov; 10(11):. PubMed ID: 34831287
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
    Jiang S; Zou Z; Nie P; Wen R; Xiao Y; Tang J
    PLoS One; 2015; 10(7):e0132880. PubMed ID: 26176608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
    Lee D; Sykes SM; Kalaitzidis D; Lane AA; Kfoury Y; Raaijmakers MH; Wang YH; Armstrong SA; Scadden DT
    Stem Cell Reports; 2014 Nov; 3(5):832-40. PubMed ID: 25418727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects.
    Jhanwar-Uniyal M; Amin AG; Cooper JB; Das K; Schmidt MH; Murali R
    Adv Biol Regul; 2017 May; 64():39-48. PubMed ID: 28189457
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition.
    Firat E; Niedermann G
    Oncotarget; 2016 Aug; 7(34):54883-54896. PubMed ID: 27448972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
    Hagiwara A; Cornu M; Cybulski N; Polak P; Betz C; Trapani F; Terracciano L; Heim MH; Rüegg MA; Hall MN
    Cell Metab; 2012 May; 15(5):725-38. PubMed ID: 22521878
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.
    Boreddy SR; Pramanik KC; Srivastava SK
    Clin Cancer Res; 2011 Apr; 17(7):1784-95. PubMed ID: 21350002
    [TBL] [Abstract][Full Text] [Related]  

  • 18. mTORC2 links growth factor signaling with epigenetic regulation of iron metabolism in glioblastoma.
    Masui K; Harachi M; Ikegami S; Yang H; Onizuka H; Yong WH; Cloughesy TF; Muragaki Y; Kawamata T; Arai N; Komori T; Cavenee WK; Mischel PS; Shibata N
    J Biol Chem; 2019 Dec; 294(51):19740-19751. PubMed ID: 31712311
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer.
    Zheng G; Jia X; Peng C; Deng Y; Yin J; Zhang Z; Li N; Deng M; Liu X; Liu H; Lu M; Wang C; Gu Y; He Z
    Oncotarget; 2015 Mar; 6(9):6931-43. PubMed ID: 25749387
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IBP-mediated suppression of autophagy promotes growth and metastasis of breast cancer cells via activating mTORC2/Akt/FOXO3a signaling pathway.
    Chen S; Han Q; Wang X; Yang M; Zhang Z; Li P; Chen A; Hu C; Li S
    Cell Death Dis; 2013 Oct; 4(10):e842. PubMed ID: 24113176
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.