These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 2414022)

  • 1. Insulin effects on methotrexate polyglutamate synthesis and enzyme binding in cultured human breast cancer cells.
    Schilsky RL; Ordway FS
    Cancer Chemother Pharmacol; 1985; 15(3):272-7. PubMed ID: 2414022
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, binding and intracellular retention of methotrexate polyglutamates by cultured human breast cancer cells.
    Schilsky RL; Jolivet J; Bailey BD; Chabner BA
    Adv Exp Med Biol; 1983; 163():247-57. PubMed ID: 6193688
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The kinetics of methotrexate polyglutamation in human breast cancer cells.
    Morrison PF; Allegra CJ
    Arch Biochem Biophys; 1987 May; 254(2):597-610. PubMed ID: 2437860
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Methotrexate polyglutamate synthesis by cultured human breast cancer cells.
    Schilsky RL; Bailey BD; Chabner BA
    Proc Natl Acad Sci U S A; 1980 May; 77(5):2919-22. PubMed ID: 6156458
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, retention, and biological activity of methotrexate polyglutamates in cultured human breast cancer cells.
    Jolivet J; Schilsky RL; Bailey BD; Drake JC; Chabner BA
    J Clin Invest; 1982 Aug; 70(2):351-60. PubMed ID: 6178756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates.
    Cowan KH; Jolivet J
    J Biol Chem; 1984 Sep; 259(17):10793-800. PubMed ID: 6206061
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interaction of methotrexate polyglutamates and dihydrofolate during leucovorin rescue in a human breast cancer cell line (MCF-7).
    Allegra CJ; Boarman D
    Cancer Res; 1990 Jun; 50(12):3574-8. PubMed ID: 1692762
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Methotrexate metabolism in mutant Chinese hamster ovary cells lacking dihydrofolate reductase.
    Joannon P; Whitehead VM; Rosenblatt DS; Vuchich MJ; Beaulieu D
    Biochem Pharmacol; 1987 Apr; 36(7):1091-7. PubMed ID: 2436625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effect of leucovorin on the synthesis of methotrexate poly-gamma-glutamates in the MCF-7 human breast cancer cell line.
    Kennedy DG; Van den Berg HW; Clarke R; Murphy RF
    Biochem Pharmacol; 1985 Aug; 34(16):2897-903. PubMed ID: 2411271
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
    Barakat RR; Li WW; Lovelace C; Bertino JR
    Gynecol Oncol; 1993 Oct; 51(1):54-60. PubMed ID: 7694891
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of methotrexate polyglutamates in methotrexate- and sequential methotrexate-5-fluorouracil-mediated cell kill.
    McGuire JJ; Mini E; Hsieh P; Bertino JR
    Cancer Res; 1985 Dec; 45(12 Pt 1):6395-400. PubMed ID: 2415244
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methotrexate polyglutamates in cultured human cells.
    Rosenblatt DS; Whitehead VM
    Adv Exp Med Biol; 1983; 163():275-85. PubMed ID: 6193690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulatory aspects of the glutamylation of methotrexate in cultured hepatoma cells.
    Nimec Z; Galivan J
    Arch Biochem Biophys; 1983 Oct; 226(2):671-80. PubMed ID: 6195970
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on the in vivo synthesis of methotrexate polyglutamates and their efflux properties in normal, proliferative, and neoplastic mouse tissues.
    Poser RG; Sirotnak FM
    Adv Exp Med Biol; 1983; 163():259-74. PubMed ID: 6193689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The kinetics of methotrexate polyglutamate formation and efflux in a human breast cancer cell line (MDA.MB.436): the effect of insulin.
    Kennedy DG; Clarke R; van den Berg HW; Murphy RF
    Biochem Pharmacol; 1983 Jan; 32(1):41-6. PubMed ID: 6187348
    [No Abstract]   [Full Text] [Related]  

  • 17. Formation of methotrexate polyglutamates in rat hepatocytes.
    Gewirtz DA; White JC; Randolph JK; Goldman ID
    Cancer Res; 1979 Aug; 39(8):2914-8. PubMed ID: 455278
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug.
    Pizzorno G; Mini E; Coronnello M; McGuire JJ; Moroson BA; Cashmore AR; Dreyer RN; Lin JT; Mazzei T; Periti P
    Cancer Res; 1988 Apr; 48(8):2149-55. PubMed ID: 2450647
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates.
    Goldman ID; Matherly LH
    NCI Monogr; 1987; (5):17-26. PubMed ID: 2448654
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin-dependent suppression in glutamyl hydrolase activity and elevated cellular methotrexate polyglutamates.
    Galivan J; Rhee MS
    Biochem Pharmacol; 1995 Nov; 50(10):1659-63. PubMed ID: 7503769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.