These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 24140631)

  • 1. Optimization of upcyte® human hepatocytes for the in vitro micronucleus assay.
    Nörenberg A; Heinz S; Scheller K; Hewitt NJ; Braspenning J; Ott M
    Mutat Res Genet Toxicol Environ Mutagen; 2013 Dec; 758(1-2):69-79. PubMed ID: 24140631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Generation of proliferating human hepatocytes using Upcyte® technology: characterisation and applications in induction and cytotoxicity assays.
    Burkard A; Dähn C; Heinz S; Zutavern A; Sonntag-Buck V; Maltman D; Przyborski S; Hewitt NJ; Braspenning J
    Xenobiotica; 2012 Oct; 42(10):939-56. PubMed ID: 22524704
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies.
    Schulz C; Kammerer S; Küpper JH
    Clin Hemorheol Microcirc; 2019; 73(1):249-260. PubMed ID: 31561354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.
    Tolosa L; Gómez-Lechón MJ; López S; Guzmán C; Castell JV; Donato MT; Jover R
    Toxicol Sci; 2016 Jul; 152(1):214-29. PubMed ID: 27208088
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies.
    Ramachandran SD; Vivarès A; Klieber S; Hewitt NJ; Muenst B; Heinz S; Walles H; Braspenning J
    Pharmacol Res Perspect; 2015 Oct; 3(5):e00161. PubMed ID: 26516577
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Generation & characterization of expandable human liver sinusoidal endothelial cells and their application to assess hepatotoxicity in an advanced in vitro liver model.
    Kaden T; Noerenberg A; Boldt J; Sagawe C; Johannssen T; Rennert K; Raasch M; Evenburg T
    Toxicology; 2023 Jan; 483():153374. PubMed ID: 36396002
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of the in vitro rat hepatocyte micronucleus assay in genetic toxicology testing.
    Müller-Tegethoff K; Kersten B; Kasper P; Müller L
    Mutat Res; 1997 Aug; 392(1-2):125-38. PubMed ID: 9269337
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): a study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group.
    ; Suzuki H; Takasawa H; Kobayashi K; Terashima Y; Shimada Y; Ogawa I; Tanaka J; Imamura T; Miyazaki A; Hayashi M
    Mutagenesis; 2009 Jan; 24(1):9-16. PubMed ID: 18765420
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo micronucleus screening in zebrafish by flow cytometry.
    Le Bihanic F; Di Bucchianico S; Karlsson HL; Dreij K
    Mutagenesis; 2016 Nov; 31(6):643-653. PubMed ID: 27386876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
    Rothfuss A; O'Donovan M; De Boeck M; Brault D; Czich A; Custer L; Hamada S; Plappert-Helbig U; Hayashi M; Howe J; Kraynak AR; van der Leede BJ; Nakajima M; Priestley C; Thybaud V; Saigo K; Sawant S; Shi J; Storer R; Struwe M; Vock E; Galloway S
    Mutat Res; 2010 Sep; 702(1):40-69. PubMed ID: 20656055
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An adaptation of the human HepaRG cells to the in vitro micronucleus assay.
    Jossé R; Rogue A; Lorge E; Guillouzo A
    Mutagenesis; 2012 May; 27(3):295-304. PubMed ID: 22058015
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An Adaption of Human-Induced Hepatocytes to In Vitro Genetic Toxicity Tests.
    Liu W; Xi J; Cao Y; You X; Chen R; Zhang X; Han L; Pan G; Luan Y
    Mutagenesis; 2019 May; 34(2):165-171. PubMed ID: 30590776
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds.
    Schaefer M; Schänzle G; Bischoff D; Süssmuth RD
    Drug Metab Dispos; 2016 Mar; 44(3):435-44. PubMed ID: 26712819
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An assessment of the in vitro hepatocyte micronucleus assay.
    Müller K; Kasper P; Müller L
    Mutat Res; 1993 Dec; 292(3):213-24. PubMed ID: 7504181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evaluation of a repeated dose liver micronucleus assay in rats treated with two genotoxic hepatocarcinogens, dimethylnitrosamine and 2-acetylaminofluorene: the possibility of integrating micronucleus tests with multiple tissues into a repeated dose general toxicity study.
    Takashima R; Takasawa H; Kawasako K; Ohyama W; Okada E; Narumi K; Fujiishi Y; Wako Y; Yasunaga K; Hattori A; Kawabata M; Nakadate K; Nakagawa M; Hamada S
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Mar; 780-781():18-24. PubMed ID: 25892620
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Micronucleus induction in rat liver and bone marrow by acute vs. repeat doses of the genotoxic hepatocarcinogen monocrotaline.
    Takashima R; Takasawa H; Wako Y; Yasunaga K; Hattori A; Kawabata M; Nakadate K; Nakagawa M; Hamada S
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Mar; 780-781():64-70. PubMed ID: 25892625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Repeated-dose liver micronucleus assay of mitomycin C in young adult rats.
    Shimada K; Yamamoto M; Takashima M; Wako Y; Kawasako K; Aoki Y; Seki J; Miyamae Y; Wakata A
    Mutat Res Genet Toxicol Environ Mutagen; 2015 Mar; 780-781():85-9. PubMed ID: 24566084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability.
    Avlasevich SL; Bryce SM; Cairns SE; Dertinger SD
    Environ Mol Mutagen; 2006 Jan; 47(1):56-66. PubMed ID: 16180205
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Optimization of specimen preparation from formalin-fixed liver tissues for liver micronucleus assays: Hepatocyte staining with fluorescent dyes.
    Shigano M; Takashima R; Takasawa H; Hamada S
    Mutat Res Genet Toxicol Environ Mutagen; 2016 Apr; 800-801():35-9. PubMed ID: 27085473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Measurement of genotoxicity in wastewater samples with the in vitro micronucleus test: results of a round-robin study in the context of standardisation according to ISO.
    Reifferscheid G; Ziemann C; Fieblinger D; Dill F; Gminski R; Grummt HJ; Hafner C; Hollert H; Kunz S; Rodrigo G; Stopper H; Selke D
    Mutat Res; 2008 Jan; 649(1-2):15-27. PubMed ID: 17980648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.