BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 24141978)

  • 1. A subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy.
    Zhang L; Yang J; Cai J; Song X; Deng J; Huang X; Chen D; Yang M; Wery JP; Li S; Wu A; Li Z; Li Z; Liu Y; Chen Y; Li Q; Ji J
    Sci Rep; 2013 Oct; 3():2992. PubMed ID: 24141978
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor effect of cetuximab in combination with S-1 in EGFR-amplified gastric cancer cells.
    Fukuda K; Saikawa Y; Takahashi M; Takahashi T; Wada N; Kawakubo H; Takeuchi H; Kitagawa Y
    Int J Oncol; 2012 Apr; 40(4):975-82. PubMed ID: 22139134
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cetuximab inhibits gastric cancer growth in vivo, independent of KRAS status.
    Shi M; Shi H; Ji J; Cai Q; Chen X; Yu Y; Liu B; Zhu Z; Zhang J
    Curr Cancer Drug Targets; 2014; 14(2):217-24. PubMed ID: 24467518
    [TBL] [Abstract][Full Text] [Related]  

  • 4. EGFR gene status predicts response and survival benefit in a preclinical gastric cancer trial treating patient‑derived xenografts with cetuximab.
    Wang X; Fu R; Hu Y; Du H; Li S; Li Z; Liu Y; Li Q; Zhang L; Ji J
    Oncol Rep; 2017 Oct; 38(4):2387-2393. PubMed ID: 28849161
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro and in vivo antitumor activity of cetuximab in human gastric cancer cell lines in relation to epidermal growth factor receptor (EGFR) expression and mutational phenotype.
    Hotz B; Keilholz U; Fusi A; Buhr HJ; Hotz HG
    Gastric Cancer; 2012 Jul; 15(3):252-64. PubMed ID: 22011788
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance to cetuximab in EGFR-overexpressing esophageal squamous cell carcinoma xenografts due to FGFR2 amplification and overexpression.
    Zhang Y; Pan T; Zhong X; Cheng C
    J Pharmacol Sci; 2014; 126(1):77-83. PubMed ID: 25242085
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of EGFR or IGF-1R signaling enhances radiation response in head and neck cancer models but concurrent inhibition has no added benefit.
    Raju U; Molkentine DP; Valdecanas DR; Deorukhkar A; Mason KA; Buchholz TA; Meyn RE; Ang KK; Skinner H
    Cancer Med; 2015 Jan; 4(1):65-74. PubMed ID: 25355701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GC1118, a novel anti-EGFR antibody, has potent KRAS mutation-independent antitumor activity compared with cetuximab in gastric cancer.
    Park JE; Jin MH; Hur M; Nam AR; Bang JH; Won J; Oh DY; Bang YJ
    Gastric Cancer; 2019 Sep; 22(5):932-940. PubMed ID: 30815759
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EGFR-amplification plus gene expression profiling predicts response to combined radiotherapy with EGFR-inhibition: A preclinical trial in 10 HNSCC-tumour-xenograft models.
    Koi L; Löck S; Linge A; Thurow C; Hering S; Baumann M; Krause M; Gurtner K
    Radiother Oncol; 2017 Sep; 124(3):496-503. PubMed ID: 28807520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical modeling of EGFR inhibitor resistance in head and neck cancer.
    Quesnelle KM; Wheeler SE; Ratay MK; Grandis JR
    Cancer Biol Ther; 2012 Aug; 13(10):935-45. PubMed ID: 22785204
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of ABT-806, a Humanized Tumor-Specific Anti-EGFR Monoclonal Antibody.
    Reilly EB; Phillips AC; Buchanan FG; Kingsbury G; Zhang Y; Meulbroek JA; Cole TB; DeVries PJ; Falls HD; Beam C; Gu J; Digiammarino EL; Palma JP; Donawho CK; Goodwin NC; Scott AM
    Mol Cancer Ther; 2015 May; 14(5):1141-51. PubMed ID: 25731184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of human papilloma virus infection on the response of head and neck cancers to anti-epidermal growth factor receptor antibody therapy.
    Pogorzelski M; Ting S; Gauler TC; Breitenbuecher F; Vossebein I; Hoffarth S; Markowetz J; Lang S; Bergmann C; Brandau S; Jawad JA; Schmid KW; Schuler M; Kasper S
    Cell Death Dis; 2014 Feb; 5(2):e1091. PubMed ID: 24577089
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biomarker analysis of cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric and oesophago-gastric junction cancer: results from a phase II trial of the Arbeitsgemeinschaft Internistische Onkologie (AIO).
    Luber B; Deplazes J; Keller G; Walch A; Rauser S; Eichmann M; Langer R; Höfler H; Hegewisch-Becker S; Folprecht G; Wöll E; Decker T; Endlicher E; Lorenzen S; Fend F; Peschel C; Lordick F
    BMC Cancer; 2011 Dec; 11():509. PubMed ID: 22152101
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [EGFR-blockade by antibody Cetuximab inhibits the growth of human gastric cancer xenograft in nude mice and its possible mechanism].
    Zhang J; Ji J; Yuan F; Ma T; Ye ZB; Yu YY; Liu BY; Zhu ZG
    Zhonghua Zhong Liu Za Zhi; 2009 Feb; 31(2):85-9. PubMed ID: 19538880
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer.
    Keysar SB; Le PN; Anderson RT; Morton JJ; Bowles DW; Paylor JJ; Vogler BW; Thorburn J; Fernandez P; Glogowska MJ; Takimoto SM; Sehrt DB; Gan GN; Eagles-Soukup JR; Serracino H; Hirsch FR; Lucia MS; Thorburn A; Song JI; Wang XJ; Jimeno A
    Cancer Res; 2013 Jun; 73(11):3381-92. PubMed ID: 23576557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer.
    Bardelli A; Corso S; Bertotti A; Hobor S; Valtorta E; Siravegna G; Sartore-Bianchi A; Scala E; Cassingena A; Zecchin D; Apicella M; Migliardi G; Galimi F; Lauricella C; Zanon C; Perera T; Veronese S; Corti G; Amatu A; Gambacorta M; Diaz LA; Sausen M; Velculescu VE; Comoglio P; Trusolino L; Di Nicolantonio F; Giordano S; Siena S
    Cancer Discov; 2013 Jun; 3(6):658-73. PubMed ID: 23729478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies.
    Cho J; Pastorino S; Zeng Q; Xu X; Johnson W; Vandenberg S; Verhaak R; Cherniack AD; Watanabe H; Dutt A; Kwon J; Chao YS; Onofrio RC; Chiang D; Yuza Y; Kesari S; Meyerson M
    Cancer Res; 2011 Dec; 71(24):7587-96. PubMed ID: 22001862
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization and validation of potential therapeutic targets based on the molecular signature of patient-derived xenografts in gastric cancer.
    Chen Z; Huang W; Tian T; Zang W; Wang J; Liu Z; Li Z; Lai Y; Jiang Z; Gao J; Shen L
    J Hematol Oncol; 2018 Feb; 11(1):20. PubMed ID: 29433585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption.
    Larbouret C; Gaborit N; Chardès T; Coelho M; Campigna E; Bascoul-Mollevi C; Mach JP; Azria D; Robert B; Pèlegrin A
    Neoplasia; 2012 Feb; 14(2):121-30. PubMed ID: 22431920
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinical Utility of Patient-Derived Xenografts to Determine Biomarkers of Prognosis and Map Resistance Pathways in EGFR-Mutant Lung Adenocarcinoma.
    Stewart EL; Mascaux C; Pham NA; Sakashita S; Sykes J; Kim L; Yanagawa N; Allo G; Ishizawa K; Wang D; Zhu CQ; Li M; Ng C; Liu N; Pintilie M; Martin P; John T; Jurisica I; Leighl NB; Neel BG; Waddell TK; Shepherd FA; Liu G; Tsao MS
    J Clin Oncol; 2015 Aug; 33(22):2472-80. PubMed ID: 26124487
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.