164 related articles for article (PubMed ID: 24145545)
1. Human cytomegalovirus UL97 kinase is involved in the mechanism of action of methylenecyclopropane analogs with 6-ether and -thioether substitutions.
Komazin-Meredith G; Chou S; Prichard MN; Hartline CB; Cardinale SC; Comeau K; Williams JD; Khan AR; Peet NP; Bowlin TL
Antimicrob Agents Chemother; 2014; 58(1):274-8. PubMed ID: 24145545
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.
Prichard MN; Williams JD; Komazin-Meredith G; Khan AR; Price NB; Jefferson GM; Harden EA; Hartline CB; Peet NP; Bowlin TL
Antimicrob Agents Chemother; 2013 Aug; 57(8):3518-27. PubMed ID: 23669381
[TBL] [Abstract][Full Text] [Related]
3. Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives.
Chou S; Komazin-Meredith G; Williams JD; Bowlin TL
Antimicrob Agents Chemother; 2014; 58(3):1809-12. PubMed ID: 24379208
[TBL] [Abstract][Full Text] [Related]
4. Cytomegalovirus UL97 kinase catalytic domain mutations that confer multidrug resistance.
Chou S; Ercolani RJ; Marousek G; Bowlin TL
Antimicrob Agents Chemother; 2013 Jul; 57(7):3375-9. PubMed ID: 23650173
[TBL] [Abstract][Full Text] [Related]
5. TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate.
Komazin-Meredith G; Cardinale SC; Comeau K; Magalhaes KJ; Hartline CB; Williams JD; Opperman TJ; Prichard MN; Bowlin TL
Antiviral Res; 2015 Jul; 119():23-7. PubMed ID: 25857706
[TBL] [Abstract][Full Text] [Related]
6. Cyclopropavir inhibits the normal function of the human cytomegalovirus UL97 kinase.
James SH; Hartline CB; Harden EA; Driebe EM; Schupp JM; Engelthaler DM; Keim PS; Bowlin TL; Kern ER; Prichard MN
Antimicrob Agents Chemother; 2011 Oct; 55(10):4682-91. PubMed ID: 21788463
[TBL] [Abstract][Full Text] [Related]
7. Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.
Talarico CL; Burnette TC; Miller WH; Smith SL; Davis MG; Stanat SC; Ng TI; He Z; Coen DM; Roizman B; Biron KK
Antimicrob Agents Chemother; 1999 Aug; 43(8):1941-6. PubMed ID: 10428917
[TBL] [Abstract][Full Text] [Related]
8. Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.
Kushner NL; Williams SL; Hartline CB; Harden EA; Bidanset DJ; Chen X; Zemlicka J; Kern ER
Nucleosides Nucleotides Nucleic Acids; 2003 Dec; 22(12):2105-19. PubMed ID: 14714760
[TBL] [Abstract][Full Text] [Related]
9. Cytomegalovirus UL97 mutations affecting cyclopropavir and ganciclovir susceptibility.
Chou S; Bowlin TL
Antimicrob Agents Chemother; 2011 Jan; 55(1):382-4. PubMed ID: 21041510
[TBL] [Abstract][Full Text] [Related]
10. Single and multiple mutations in the human cytomegalovirus UL97 gene and their relationship to the enzymatic activity of UL97 kinase for ganciclovir phosphorylation.
Sanchez Puch SI; Mathet VL; Porta M; Cuestas ML; Oubiña JR; Videla CM; Salomón HE
Antiviral Res; 2009 Nov; 84(2):194-8. PubMed ID: 19712701
[TBL] [Abstract][Full Text] [Related]
11. Z-isomers of 2-hydroxymethylcyclopropylidenemethyl adenine (synadenol) and guanine (synguanol) are active against ganciclovir- and foscarnet-resistant human cytomegalovirus UL97 mutants.
Baldanti F; Sarasini A; Drach JC; Zemlicka J; Gerna G
Antiviral Res; 2002 Dec; 56(3):273-8. PubMed ID: 12406510
[TBL] [Abstract][Full Text] [Related]
12. Resistance of human cytomegalovirus to cyclopropavir maps to a base pair deletion in the open reading frame of UL97.
Gentry BG; Vollmer LE; Hall ED; Borysko KZ; Zemlicka J; Kamil JP; Drach JC
Antimicrob Agents Chemother; 2013 Sep; 57(9):4343-8. PubMed ID: 23817384
[TBL] [Abstract][Full Text] [Related]
13. Effects on maribavir susceptibility of cytomegalovirus UL97 kinase ATP binding region mutations detected after drug exposure in vitro and in vivo.
Chou S; Hakki M; Villano S
Antiviral Res; 2012 Aug; 95(2):88-92. PubMed ID: 22664236
[TBL] [Abstract][Full Text] [Related]
14. Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity.
Mhaske SB; Ksebati B; Prichard MN; Drach JC; Zemlicka J
Bioorg Med Chem; 2009 Jun; 17(11):3892-9. PubMed ID: 19410465
[TBL] [Abstract][Full Text] [Related]
15. Novel UL97 drug resistance mutations identified at baseline in a clinical trial of maribavir for resistant or refractory cytomegalovirus infection.
Chou S; Wu J; Song K; Bo T
Antiviral Res; 2019 Dec; 172():104616. PubMed ID: 31568799
[TBL] [Abstract][Full Text] [Related]
16. Expression of the human cytomegalovirus UL97 gene in a chimeric guinea pig cytomegalovirus (GPCMV) results in viable virus with increased susceptibility to ganciclovir and maribavir.
McGregor A; Choi KY; Cui X; McVoy MA; Schleiss MR
Antiviral Res; 2008 Jun; 78(3):250-9. PubMed ID: 18325607
[TBL] [Abstract][Full Text] [Related]
17. Rapid semiquantitative real-time PCR for the detection of human cytomegalovirus UL97 mutations conferring ganciclovir resistance.
Göhring K; Mikeler E; Jahn G; Rohde F; Hamprecht K
Antivir Ther; 2008; 13(3):461-6. PubMed ID: 18572760
[TBL] [Abstract][Full Text] [Related]
18. Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase.
Tenney DJ; Yamanaka G; Voss SM; Cianci CW; Tuomari AV; Sheaffer AK; Alam M; Colonno RJ
Antimicrob Agents Chemother; 1997 Dec; 41(12):2680-5. PubMed ID: 9420038
[TBL] [Abstract][Full Text] [Related]
19. Diverse cytomegalovirus UL27 mutations adapt to loss of viral UL97 kinase activity under maribavir.
Chou S
Antimicrob Agents Chemother; 2009 Jan; 53(1):81-5. PubMed ID: 18981262
[TBL] [Abstract][Full Text] [Related]
20. Cytomegalovirus UL97 kinase mutations that confer maribavir resistance.
Chou S; Wechel LC; Marousek GI
J Infect Dis; 2007 Jul; 196(1):91-4. PubMed ID: 17538888
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
