301 related articles for article (PubMed ID: 24149002)
1. Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis.
Marschall M; Niemann I; Kosulin K; Bootz A; Wagner S; Dobner T; Herz T; Kramer B; Leban J; Vitt D; Stamminger T; Hutterer C; Strobl S
Antiviral Res; 2013 Dec; 100(3):640-8. PubMed ID: 24149002
[TBL] [Abstract][Full Text] [Related]
2. [Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening].
Vidalain PO; Lucas-Hourani M; Helynck O; Tangy F; Munier-Lehmann H
Med Sci (Paris); 2015 Jan; 31(1):98-104. PubMed ID: 25658737
[TBL] [Abstract][Full Text] [Related]
3. Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH).
Munier-Lehmann H; Lucas-Hourani M; Guillou S; Helynck O; Zanghi G; Noel A; Tangy F; Vidalain PO; Janin YL
J Med Chem; 2015 Jan; 58(2):860-77. PubMed ID: 25558988
[TBL] [Abstract][Full Text] [Related]
4. Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
Lucas-Hourani M; Munier-Lehmann H; El Mazouni F; Malmquist NA; Harpon J; Coutant EP; Guillou S; Helynck O; Noel A; Scherf A; Phillips MA; Tangy F; Vidalain PO; Janin YL
J Med Chem; 2015 Jul; 58(14):5579-98. PubMed ID: 26079043
[TBL] [Abstract][Full Text] [Related]
5. Potent antiviral activity of brequinar against the emerging Cantagalo virus in cell culture.
Schnellrath LC; Damaso CR
Int J Antimicrob Agents; 2011 Nov; 38(5):435-41. PubMed ID: 21840180
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of dengue virus through suppression of host pyrimidine biosynthesis.
Wang QY; Bushell S; Qing M; Xu HY; Bonavia A; Nunes S; Zhou J; Poh MK; Florez de Sessions P; Niyomrattanakit P; Dong H; Hoffmaster K; Goh A; Nilar S; Schul W; Jones S; Kramer L; Compton T; Shi PY
J Virol; 2011 Jul; 85(13):6548-56. PubMed ID: 21507975
[TBL] [Abstract][Full Text] [Related]
7. New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.
Shuto S; Obara T; Saito Y; Andrei G; Snoeck R; De Clercq E; Matsuda A
J Med Chem; 1996 Jun; 39(12):2392-9. PubMed ID: 8691433
[TBL] [Abstract][Full Text] [Related]
8. Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro.
Kim YJ; Cubitt B; Cai Y; Kuhn JH; Vitt D; Kohlhof H; de la Torre JC
Viruses; 2020 Jul; 12(8):. PubMed ID: 32751087
[TBL] [Abstract][Full Text] [Related]
9. Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication.
Luganini A; Sibille G; Mognetti B; Sainas S; Pippione AC; Giorgis M; Boschi D; Lolli ML; Gribaudo G
Antiviral Res; 2021 May; 189():105057. PubMed ID: 33716051
[TBL] [Abstract][Full Text] [Related]
10. Functional expression of human dihydroorotate dehydrogenase (DHODH) in pyr4 mutants of ustilago maydis allows target validation of DHODH inhibitors in vivo.
Zameitat E; Freymark G; Dietz CD; Löffler M; Bölker M
Appl Environ Microbiol; 2007 May; 73(10):3371-9. PubMed ID: 17369345
[TBL] [Abstract][Full Text] [Related]
11. Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors.
Grandin C; Hourani ML; Janin YL; Dauzonne D; Munier-Lehmann H; Paturet A; Taborik F; Vabret A; Contamin H; Tangy F; Vidalain PO
Antiviral Res; 2016 Jan; 125():58-62. PubMed ID: 26593978
[TBL] [Abstract][Full Text] [Related]
12. Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.
Efferth T; Marschall M; Wang X; Huong SM; Hauber I; Olbrich A; Kronschnabl M; Stamminger T; Huang ES
J Mol Med (Berl); 2002 Apr; 80(4):233-42. PubMed ID: 11976732
[TBL] [Abstract][Full Text] [Related]
13. D282, a non-nucleoside inhibitor of influenza virus infection that interferes with de novo pyrimidine biosynthesis.
Smee DF; Hurst BL; Day CW
Antivir Chem Chemother; 2012 Aug; 22(6):263-72. PubMed ID: 22516927
[TBL] [Abstract][Full Text] [Related]
14. A comprehensive drug repurposing study for COVID19 treatment: novel putative dihydroorotate dehydrogenase inhibitors show association to serotonin-dopamine receptors.
Berber B; Doluca O
Brief Bioinform; 2021 Mar; 22(2):1023-1037. PubMed ID: 33406218
[TBL] [Abstract][Full Text] [Related]
15. A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.
Hutterer C; Eickhoff J; Milbradt J; Korn K; Zeitträger I; Bahsi H; Wagner S; Zischinsky G; Wolf A; Degenhart C; Unger A; Baumann M; Klebl B; Marschall M
Antimicrob Agents Chemother; 2015 Apr; 59(4):2062-71. PubMed ID: 25624324
[TBL] [Abstract][Full Text] [Related]
16. Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.
Lucas-Hourani M; Dauzonne D; Munier-Lehmann H; Khiar S; Nisole S; Dairou J; Helynck O; Afonso PV; Tangy F; Vidalain PO
Antimicrob Agents Chemother; 2017 Oct; 61(10):. PubMed ID: 28807907
[No Abstract] [Full Text] [Related]
17. IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro.
Hahn F; Wangen C; Häge S; Peter AS; Dobler G; Hurst B; Julander J; Fuchs J; Ruzsics Z; Überla K; Jäck HM; Ptak R; Muehler A; Gröppel M; Vitt D; Peelen E; Kohlhof H; Marschall M
Viruses; 2020 Dec; 12(12):. PubMed ID: 33291455
[TBL] [Abstract][Full Text] [Related]
18. Discovery of a novel series of inhibitors of human cytomegalovirus primase.
Cushing TD; Adrian J; Chen X; DiMaio H; Doughan B; Flygare J; Liang L; Mayorga V; Miao S; Mellon H; Peterson MG; Powers JP; Spector F; Stein C; Wright M; Xu D; Ye Q; Jaen J
Bioorg Med Chem Lett; 2006 Sep; 16(18):4879-83. PubMed ID: 16814545
[TBL] [Abstract][Full Text] [Related]
19. Biaryl analogues of teriflunomide as potent DHODH inhibitors.
Erra M; Moreno I; Sanahuja J; Andrés M; Reinoso RF; Lozoya E; Pizcueta P; Godessart N; Castro-Palomino JC
Bioorg Med Chem Lett; 2011 Dec; 21(24):7268-72. PubMed ID: 22078215
[TBL] [Abstract][Full Text] [Related]
20. Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis.
Yang CF; Gopula B; Liang JJ; Li JK; Chen SY; Lee YL; Chen CS; Lin YL
Emerg Microbes Infect; 2018 Nov; 7(1):187. PubMed ID: 30459406
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]