BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

301 related articles for article (PubMed ID: 24149002)

  • 1. Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis.
    Marschall M; Niemann I; Kosulin K; Bootz A; Wagner S; Dobner T; Herz T; Kramer B; Leban J; Vitt D; Stamminger T; Hutterer C; Strobl S
    Antiviral Res; 2013 Dec; 100(3):640-8. PubMed ID: 24149002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening].
    Vidalain PO; Lucas-Hourani M; Helynck O; Tangy F; Munier-Lehmann H
    Med Sci (Paris); 2015 Jan; 31(1):98-104. PubMed ID: 25658737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH).
    Munier-Lehmann H; Lucas-Hourani M; Guillou S; Helynck O; Zanghi G; Noel A; Tangy F; Vidalain PO; Janin YL
    J Med Chem; 2015 Jan; 58(2):860-77. PubMed ID: 25558988
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
    Lucas-Hourani M; Munier-Lehmann H; El Mazouni F; Malmquist NA; Harpon J; Coutant EP; Guillou S; Helynck O; Noel A; Scherf A; Phillips MA; Tangy F; Vidalain PO; Janin YL
    J Med Chem; 2015 Jul; 58(14):5579-98. PubMed ID: 26079043
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent antiviral activity of brequinar against the emerging Cantagalo virus in cell culture.
    Schnellrath LC; Damaso CR
    Int J Antimicrob Agents; 2011 Nov; 38(5):435-41. PubMed ID: 21840180
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of dengue virus through suppression of host pyrimidine biosynthesis.
    Wang QY; Bushell S; Qing M; Xu HY; Bonavia A; Nunes S; Zhou J; Poh MK; Florez de Sessions P; Niyomrattanakit P; Dong H; Hoffmaster K; Goh A; Nilar S; Schul W; Jones S; Kramer L; Compton T; Shi PY
    J Virol; 2011 Jul; 85(13):6548-56. PubMed ID: 21507975
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.
    Shuto S; Obara T; Saito Y; Andrei G; Snoeck R; De Clercq E; Matsuda A
    J Med Chem; 1996 Jun; 39(12):2392-9. PubMed ID: 8691433
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro.
    Kim YJ; Cubitt B; Cai Y; Kuhn JH; Vitt D; Kohlhof H; de la Torre JC
    Viruses; 2020 Jul; 12(8):. PubMed ID: 32751087
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication.
    Luganini A; Sibille G; Mognetti B; Sainas S; Pippione AC; Giorgis M; Boschi D; Lolli ML; Gribaudo G
    Antiviral Res; 2021 May; 189():105057. PubMed ID: 33716051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional expression of human dihydroorotate dehydrogenase (DHODH) in pyr4 mutants of ustilago maydis allows target validation of DHODH inhibitors in vivo.
    Zameitat E; Freymark G; Dietz CD; Löffler M; Bölker M
    Appl Environ Microbiol; 2007 May; 73(10):3371-9. PubMed ID: 17369345
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors.
    Grandin C; Hourani ML; Janin YL; Dauzonne D; Munier-Lehmann H; Paturet A; Taborik F; Vabret A; Contamin H; Tangy F; Vidalain PO
    Antiviral Res; 2016 Jan; 125():58-62. PubMed ID: 26593978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.
    Efferth T; Marschall M; Wang X; Huong SM; Hauber I; Olbrich A; Kronschnabl M; Stamminger T; Huang ES
    J Mol Med (Berl); 2002 Apr; 80(4):233-42. PubMed ID: 11976732
    [TBL] [Abstract][Full Text] [Related]  

  • 13. D282, a non-nucleoside inhibitor of influenza virus infection that interferes with de novo pyrimidine biosynthesis.
    Smee DF; Hurst BL; Day CW
    Antivir Chem Chemother; 2012 Aug; 22(6):263-72. PubMed ID: 22516927
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A comprehensive drug repurposing study for COVID19 treatment: novel putative dihydroorotate dehydrogenase inhibitors show association to serotonin-dopamine receptors.
    Berber B; Doluca O
    Brief Bioinform; 2021 Mar; 22(2):1023-1037. PubMed ID: 33406218
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.
    Hutterer C; Eickhoff J; Milbradt J; Korn K; Zeitträger I; Bahsi H; Wagner S; Zischinsky G; Wolf A; Degenhart C; Unger A; Baumann M; Klebl B; Marschall M
    Antimicrob Agents Chemother; 2015 Apr; 59(4):2062-71. PubMed ID: 25624324
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.
    Lucas-Hourani M; Dauzonne D; Munier-Lehmann H; Khiar S; Nisole S; Dairou J; Helynck O; Afonso PV; Tangy F; Vidalain PO
    Antimicrob Agents Chemother; 2017 Oct; 61(10):. PubMed ID: 28807907
    [No Abstract]   [Full Text] [Related]  

  • 17. IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro.
    Hahn F; Wangen C; Häge S; Peter AS; Dobler G; Hurst B; Julander J; Fuchs J; Ruzsics Z; Überla K; Jäck HM; Ptak R; Muehler A; Gröppel M; Vitt D; Peelen E; Kohlhof H; Marschall M
    Viruses; 2020 Dec; 12(12):. PubMed ID: 33291455
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of a novel series of inhibitors of human cytomegalovirus primase.
    Cushing TD; Adrian J; Chen X; DiMaio H; Doughan B; Flygare J; Liang L; Mayorga V; Miao S; Mellon H; Peterson MG; Powers JP; Spector F; Stein C; Wright M; Xu D; Ye Q; Jaen J
    Bioorg Med Chem Lett; 2006 Sep; 16(18):4879-83. PubMed ID: 16814545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biaryl analogues of teriflunomide as potent DHODH inhibitors.
    Erra M; Moreno I; Sanahuja J; Andrés M; Reinoso RF; Lozoya E; Pizcueta P; Godessart N; Castro-Palomino JC
    Bioorg Med Chem Lett; 2011 Dec; 21(24):7268-72. PubMed ID: 22078215
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis.
    Yang CF; Gopula B; Liang JJ; Li JK; Chen SY; Lee YL; Chen CS; Lin YL
    Emerg Microbes Infect; 2018 Nov; 7(1):187. PubMed ID: 30459406
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.